P1-benzoxadiazole-fluorogenic-ligand
General
Type : Fluorescent Probe,Sulfur Compound,Sulfonamide,Benzoxadiazole
Chemical_Nomenclature : N-[2-(2-hexoxyethoxy)ethyl]-2-[methyl-[[7-(methylamino)-2,1,3-benzoxadiazol-4-yl]sulfonyl]amino]acetamide
Canonical SMILES : CCCCCCOCCOCCNC(=O)CN(C)S(=O)(=O)C1=CC=C(C2=NON=C12)NC
InChI : InChI=1S\/C20H33N5O6S\/c1-4-5-6-7-11-29-13-14-30-12-10-22-18(26)15-25(3)32(27,28)17-9-8-16(21-2)19-20(17)24-31-23-19\/h8-9,21H,4-7,10-15H2,1-3H3,(H,22,26)
InChIKey : BINKCYCULJAFGO-UHFFFAOYSA-N
Other name(s) : 9FM
MW : 471.6
Formula : C20H33N5O6S
CAS_number :
PubChem : 137348816
UniChem : BINKCYCULJAFGO-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : P1-benzoxadiazole-fluorogenic-ligand ligand of proteins in family: Haloalkane_dehalogenase-HLD2
Stucture : 5VNP X-ray crystal structure of Halotag bound to the P1 benzoxadiazole fluorogenic ligand
Protein : rhoso-halo1
References (1)
| Title : AgHalo: A Facile Fluorogenic Sensor to Detect Drug-Induced Proteome Stress - Liu_2017_Angew.Chem.Int.Ed.Engl_56_8672 |
| Author(s) : Liu Y , Fares M , Dunham NP , Gao Z , Miao K , Jiang X , Bollinger SS , Boal AK , Zhang X |
| Ref : Angew Chem Int Ed Engl , 56 :8672 , 2017 |
| Abstract : Liu_2017_Angew.Chem.Int.Ed.Engl_56_8672 |
| ESTHER : Liu_2017_Angew.Chem.Int.Ed.Engl_56_8672 |
| PubMedSearch : Liu_2017_Angew.Chem.Int.Ed.Engl_56_8672 |
| PubMedID: 28557281 |
| Gene_locus related to this paper: rhoso-halo1 |