Novichok-5~A-232
Novichok (newcomer/ newbie/ novice, beginner/) is a series of binary chemical weapons developed by the Soviet Union and Russia between 1971 and 1993. Mirzayanov provided the first description of these agents but are somewhat different from the structures identified later
General
Type : Organophosphate,Chemical Warfare Agent,Novichok
Chemical_Nomenclature : 3-chloro-2-methylpropyl ((chlorofluoromethylene)amino)oxyphosphonofluoridate || (1E)-1-chloro-N-[1-chloropropan-2-yloxy(fluoro)phosphoryl]oxymethanimidoyl fluoride
Canonical SMILES : CC(CCl)OP(=O)(ON=C(F)Cl)F
InChI : InChI=1S\/C4H6Cl2F2NO3P\/c1-3(2-5)11-13(8,10)12-9-4(6)7\/h3H,2H2,1H3\/b9-4-
InChIKey : FOHQFVXLTJEIKH-WTKPLQERSA-N
Other name(s) : A-232,A232,SCHEMBL21981151
MW : 255.97
Formula : C4H6Cl2F2NO3P
CAS_number : 16415-09-1
PubChem : 146586259
UniChem : FOHQFVXLTJEIKH-WTKPLQERSA-N
IUPHAR :
Wikipedia : Novichok_agent
Target
Families : Novichok-5~A-232 ligand of proteins in family: ACHE || BCHE
Stucture :
Protein : human-ACHE
References (3)
| Title : Novichok agents: a historical, current, and toxicological perspective - Chai_2018_Toxicol.Commun_2_45 |
| Author(s) : Chai PR , Hayes BD , Erickson TB , Boyer EW |
| Ref : Toxicol Commun , 2 :45 , 2018 |
| Abstract : Chai_2018_Toxicol.Commun_2_45 |
| ESTHER : Chai_2018_Toxicol.Commun_2_45 |
| PubMedSearch : Chai_2018_Toxicol.Commun_2_45 |
| PubMedID: 30003185 |
| Title : Chemical warfare agent NOVICHOK - mini-review of available data - Nepovimova_2018_Food.Chem.Toxicol_121_343 |
| Author(s) : Nepovimova E , Kuca K |
| Ref : Food & Chemical Toxicology , 121 :343 , 2018 |
| Abstract : Nepovimova_2018_Food.Chem.Toxicol_121_343 |
| ESTHER : Nepovimova_2018_Food.Chem.Toxicol_121_343 |
| PubMedSearch : Nepovimova_2018_Food.Chem.Toxicol_121_343 |
| PubMedID: 30213549 |
| Title : Novichok: a murderous nerve agent attack in the UK - |
| Author(s) : Vale JA , Marrs TO , Maynard RC |
| Ref : Clinical Toxicology (Phila) , 56 :1093 , 2018 |
| PubMedID: 29757015 |