ML114
General
Type : Thiazolidine,Sulfur Compound
Chemical_Nomenclature : [(E)-1-(1,3-thiazol-2-yl)ethylideneamino] cyclohexanecarboxylate
Canonical SMILES : CC(=NOC(=O)C1CCCCC1)C2=NC=CS2
InChI : InChI=1S\/C12H16N2O2S\/c1-9(11-13-7-8-17-11)14-16-12(15)10-5-3-2-4-6-10\/h7-8,10H,2-6H2,1H3\/b14-9+
InChIKey : RRXZTDHBRAEGPA-NTEUORMPSA-N
Other name(s) : C12H16N2O2S,CHEMBL1092791,SR-01000307014,CHEBI:92614,BDBM50314727
MW : 252.33
Formula :
CAS_number :
PubChem : 5934766
UniChem : RRXZTDHBRAEGPA-NTEUORMPSA-N
IUPHAR :
Wikipedia :
Target
Families : ML114 ligand of proteins in family: Hydrolase_RBBP9_YdeN
Stucture :
Protein : human-RBBP9
References (3)
| Title : Application of the RBBP9 Serine Hydrolase Inhibitor, ML114, Decouples Human Pluripotent Stem Cell Proliferation and Differentiation - Lim_2020_Int.J.Mol.Sci_21_8983 |
| Author(s) : Lim S , Shparberg RA , Coorssen JR , O'Connor MD |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : Lim_2020_Int.J.Mol.Sci_21_8983 |
| ESTHER : Lim_2020_Int.J.Mol.Sci_21_8983 |
| PubMedSearch : Lim_2020_Int.J.Mol.Sci_21_8983 |
| PubMedID: 33256189 |
| Gene_locus related to this paper: human-RBBP9 |
| Title : Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9) - Bachovchin_2010_Bioorg.Med.Chem.Lett_20_2254 |
| Author(s) : Bachovchin DA , Wolfe MR , Masuda K , Brown SJ , Spicer TP , Fernandez-Vega V , Chase P , Hodder PS , Rosen H , Cravatt BF |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :2254 , 2010 |
| Abstract : Bachovchin_2010_Bioorg.Med.Chem.Lett_20_2254 |
| ESTHER : Bachovchin_2010_Bioorg.Med.Chem.Lett_20_2254 |
| PubMedSearch : Bachovchin_2010_Bioorg.Med.Chem.Lett_20_2254 |
| PubMedID: 20207142 |
| Gene_locus related to this paper: human-RBBP9 |
| Title : Probe Report for RBBP9 Inhibitors - Probe 2 - Bachovchin_2010_Probe.Report.1__ |
| Author(s) : Bachovchin DA , Speers AE , Brown SJ , Cravatt BF , Spicer T , Mercer BA , Ferguson J , Hodder P , Rosen HR |
| Ref : Probe Report , : , 2010 |
| Abstract : Bachovchin_2010_Probe.Report.1__ |
| ESTHER : Bachovchin_2010_Probe.Report.1__ |
| PubMedSearch : Bachovchin_2010_Probe.Report.1__ |
| PubMedID: 21433382 |
| Gene_locus related to this paper: human-RBBP9 |