LIR
General
Type : Cyanide,Piperidine,Imidazole
Chemical_Nomenclature : 2-[[2-[(3S)-3-aminopiperidin-1-yl]-5-methyl-4,6-dioxopyrrolo[3,4-d]imidazol-3-yl]methyl]benzonitrile
Canonical SMILES : CN1C(=O)C2=C(C1=O)N(C(=N2)N3CCCC(C3)N)CC4=CC=CC=C4C#N
InChI : InChI=1S\/C19H20N6O2\/c1-23-17(26)15-16(18(23)27)25(10-13-6-3-2-5-12(13)9-20)19(22-15)24-8-4-7-14(21)11-24\/h2-3,5-6,14H,4,7-8,10-11,21H2,1H3\/t14-\/m0\/s1
InChIKey : WVRGIUWTFUXDGX-AWEZNQCLSA-N
Other name(s) : inhibitor no 7,2-[(3s)-3-Aminopiperidin-1-Yl]-1-(2-Cyanobenzyl)-5-Methyl-4,6-Dioxo-3,4,5,6-Tetrahydropyrrolo[3,4-D]imidazol-1-Ium
MW : 364.40
Formula : C19H20N6O2
CAS_number :
PubChem : 11987865
UniChem : WVRGIUWTFUXDGX-AWEZNQCLSA-N
IUPHAR :
Wikipedia :
Target
Families : LIR ligand of proteins in family: DPP4N_Peptidase_S9
Stucture : 2I3Z rat DPP-IV with xanthine mimetic inhibitor no 7
Protein : ratno-dpp4
References (1)
| Title : Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors - Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| Author(s) : Kurukulasuriya R , Rohde JJ , Szczepankiewicz BG , Basha F , Lai C , Jae HS , Winn M , Stewart KD , Longenecker KL , Lubben TW , Ballaron SJ , Sham HL , von Geldern TW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :6226 , 2006 |
| Abstract : Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| ESTHER : Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| PubMedSearch : Kurukulasuriya_2006_Bioorg.Med.Chem.Lett_16_6226 |
| PubMedID: 17010607 |
| Gene_locus related to this paper: ratno-dpp4 |