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Inhibitor Report for: KK073

KK073 induced formation of the D14-D53 complex (KK052 inhibited SL-induced formation of the D14-D53 complex)


General
Type Urea derivative, Trifluoro, Triazol
Chemical_Nomenclature 1,2,3-triazol-1-yl-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Canonical SMILES FC(F)(F)c1ccc(cc1)N1CCN(CC1)C(=O)n1ccnn1
InChI InChI=1S/C14H14F3N5O/c15-14(16,17)11-1-3-12(4-2-11)20-7-9-21(10-8-20)13(23)22-6-5-18-19-22/h1-6H,7-10H2
InChIKey HHQYTTYRIFYYCO-UHFFFAOYSA-N
Other name(s) 9GU
________________________________________________________________________________________________
MW|325.29
Formula|C14H14F3N5O
CAS_number|
PubChem|137348821
UniChem|HHQYTTYRIFYYCO-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | KK073 ligand of proteins in family: RsbQ-like
Stucture | 1 structure: 5ZHT: Crystal structure of OsD14 in complex with covalently bound KK073
Protein | orysj-Q10QA5

References:
Search PubMed for references concerning: KK073
    Title: Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses
    Nakamura H, Hirabayashi K, Miyakawa T, Kikuzato K, Hu W, Xu Y, Jiang K, Takahashi I, Niiyama R and Asami T <2 more author(s)>
    Ref: Mol Plant, 12:44, 2019 : PubMed