Inhibitor Report for: JNH General
Type Biphenyl , Pyrrolidine Chemical_Nomenclature (2S)-2-amino-1-[(2S)-2-(aminomethyl)pyrrolidin-1-yl]-3-(4-phenylphenyl)propan-1-one Canonical SMILES C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)C3=CC=CC=C3)N)CN InChI InChI=1S/C20H25N3O/c21-14-18-7-4-12-23(18)20(24)19(22)13-15-8-10-17(11-9-15)16-5-2-1-3-6-16/h1-3,5-6,8-11,18-19H,4,7,12-14,21-22H2/t18-,19-/m0/s1 InChIKey MUUVLSCVDXKQQV-OALUTQOASA-N Other name(s) (2S)-2-amino-1-[(2S)-2-(aminomethyl)pyrrolidin-1-yl]-3-(4-phenylphenyl)propan-1-one ; 2ajl ; AC1NURHX ; DB08024
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Target
Families | JNH ligand of proteins in family: DPP4N_Peptidase_S9 Stucture | 1 structure : 2AJL : X-ray Structure of Novel Biaryl-Based Dipeptidyl peptidase IV inhibitor Protein | human-DPP4
References:
Search PubMed for references concerning:
JNH
Title: Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitorsQiao L , Baumann CA , Crysler CS , Ninan NS , Abad MC , Spurlino JC , Desjarlais RL , Kervinen J , Neeper MP and Moriarty KJ <7 more author(s)> Qiao L , Baumann CA , Crysler CS , Ninan NS , Abad MC , Spurlino JC , Desjarlais RL , Kervinen J , Neeper MP , Bayoumy SS , Williams R , Deckman IC , Dasgupta M , Reed RL , Huebert ND , Tomczuk BE , Moriarty KJ (- 7) Ref: Bioorganic & Medicinal Chemistry Lett, 16 :123, 2006 : PubMed Abstract
