Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: Hydroxy-D-ring

a reaction product of trigolactones (SL), D-ring is trapped in the catalytic cavity of D14. Strigolactones (SL) are butenolide (D-ring) plant hormones with tricyclic lactone, that influence root branching leaf shape and senescence.


General
Type Butenolide, Plant hormone, Strigolactone receptors ligand, Strigolactone, Natural
Chemical_Nomenclature (5R)-5-hydroxy-3-methyloxolan-2-one
Canonical SMILES CC1CC(OC1=O)O
InChI InChI=1S/C5H8O3/c1-3-2-4(6)8-5(3)7/h3-4,6H,2H2,1H3/t3?,4-/m1/s1
InChIKey ATFSUVUJMKALFI-SRBOSORUSA-N
Other name(s) (5r)-5-Hydroxy-3-Methylfuran-2(5h)-One ; 5-hydroxy-3-methylbutenolide ; D-OH ; hydroxy D-ring ; H3M
________________________________________________________________________________________________
MW|116.11
Formula|C5H8O3
CAS_number|
PubChem|71741429
UniChem|ATFSUVUJMKALFI-SRBOSORUSA-N
IUPHAR|
Wikipedia|

Target
Families | Hydroxy-D-ring ligand of proteins in family: RsbQ-like
Stucture | 2 structures: 7K38, 3WIO
Protein | orysj-Q10QA5

References:
Search PubMed for references concerning: Hydroxy-D-ring
    Title: Structural and functional analyses explain Pea KAI2 receptor diversity and reveal stereoselective catalysis during signal perception
    Guercio AM, Torabi S, Cornu D, Dalmais M, Bendahmane A, Le Signor C, Pillot JP, Le Bris P, Boyer FD and Shabek N <3 more author(s)>
    Ref: Commun Biol, 5:126, 2022 : PubMed

            

    Title: Molecular mechanism of strigolactone perception by DWARF14
    Nakamura H, Xue YL, Miyakawa T, Hou F, Qin HM, Fukui K, Shi X, Ito E, Ito S and Asami T <6 more author(s)>
    Ref: Nat Commun, 4:2613, 2013 : PubMed