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HEPES

Component of many buffers and also found in many protein structures as a result of purification protocol

General

Type : Buffer Component,Piperazine,Sulfur Compound

Chemical_Nomenclature : 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

Canonical SMILES : C1CN(CCN1CCO)CCS(=O)(=O)O

InChI : InChI=1S\/C8H18N2O4S\/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14\/h11H,1-8H2,(H,12,13,14)

InChIKey : JKMHFZQWWAIEOD-UHFFFAOYSA-N

Other name(s) : 2-(4-(2-Hydroxyethyl)piperazin-1-yl)ethanesulfonic acid,4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid,1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-,2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

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MW : 238.30

Formula : C8H18N2O4S

CAS_number : 7365-45-9

PubChem : 23831

UniChem : JKMHFZQWWAIEOD-UHFFFAOYSA-N

Target

Families : HEPES ligand of proteins in family
Hormone-sensitive_lipase_like

Protein :
aliac-est2 lacpl-LP.2923

References (1)

1. A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase

Title : A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase - De Simone_2000_J.Mol.Biol_303_761

Author(s) : De Simone G , Galdiero S , Manco G , Lang D , Rossi M , Pedone C

Ref : Journal of Molecular Biology , 303 :761 , 2000

Abstract : De Simone_2000_J.Mol.Biol_303_761

ESTHER : De Simone_2000_J.Mol.Biol_303_761

PubMedSearch : De Simone_2000_J.Mol.Biol_303_761

PubMedID: 11061974

Gene_locus related to this paper: aliac-est2

Array
(
    [id] => 3450
    [inhibitor] => HEPES
    [type] => Array
        (
            [0] => Buffer Component
            [1] => Piperazine
            [2] => Sulfur Compound
        )

    [other_name] => Array
        (
            [0] => 2-(4-(2-Hydroxyethyl)piperazin-1-yl)ethanesulfonic acid
            [1] => 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid
            [2] => 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-
            [3] => 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
        )

    [chemical_nomenclature] => 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
    [formula] => C8H18N2O4S
    [cas_number] => 7365-45-9
    [mw] => 238.30
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => De Simone_2000_J.Mol.Biol_303_761
    [comment] => Component of many buffers and also found in many protein structures as a result of purification protocol
    [gene_locus] => aliac-est2 || lacpl-LP.2923
    [kin_inhibitor] => 
    [cid] => 23831
    [family] => Hormone-sensitive_lipase_like
    [inchikey] => JKMHFZQWWAIEOD-UHFFFAOYSA-N
    [canonicalsmiles] => C1CN(CCN1CCO)CCS(=O)(=O)O
    [inchi] => InChI=1S\/C8H18N2O4S\/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14\/h11H,1-8H2,(H,12,13,14)
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)