Diethyltabun
Synthesized (1898) in Rostock by the pharmacist Adolph Schall (1870-1957), a graduate student of August Michaelis (1847-1916). Chemical structure of the Schall compound (1903) by Michaelis. Recognition in 1937 of the toxicity of class by Gerhard Schrader (1903-1990). Confirmation (1951) of the structure by Bo Holmstedt (1919-2002)
General
Type : Cyanide,Chemical Warfare Agent,Organophosphate,Nerve Agent G-series
Chemical_Nomenclature : [diethylamino(ethoxy)phosphoryl]formonitrile
Canonical SMILES : CCN(CC)P(=O)(C#N)OCC
InChI : InChI=1S\/C7H15N2O2P\/c1-4-9(5-2)12(10,7-8)11-6-3\/h4-6H2,1-3H3
InChIKey : HDYJVARKGBRVLF-UHFFFAOYSA-N
Other name(s) : ethyl N-diethylphosphoramido cyanidate,BRN 1775808,Diethylamido-ethoxy-phosphoryl cyanide,Ethyl-N-diethyl phosphoramidocyanidate,Phosphoramidocyanidic acid, N,N-diethyl-, ethyl ester,Ethyl diethylphosphoramidocyanidate,Ethyl-N-diethylphosphoramidocyanidate
MW : 204,21
Formula : C8H17N2O2P
CAS_number : 63815-60-1
PubChem : 114261
UniChem : HDYJVARKGBRVLF-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (3)
| Title : Pharmacists Adolf Schall and Ernst Ratzlaff and the synthesis of tabun-like compounds: a brief history - Petroianu_2014_Pharmazie_69_780 |
| Author(s) : Petroianu GA |
| Ref : Pharmazie , 69 :780 , 2014 |
| Abstract : Petroianu_2014_Pharmazie_69_780 |
| ESTHER : Petroianu_2014_Pharmazie_69_780 |
| PubMedSearch : Petroianu_2014_Pharmazie_69_780 |
| PubMedID: 25985570 |
| Title : Kinetic analysis of reactivation and aging of human acetylcholinesterase inhibited by different phosphoramidates - Worek_2007_Biochem.Pharmacol_73_1807 |
| Author(s) : Worek F , Aurbek N , Koller M , Becker C , Eyer P , Thiermann H |
| Ref : Biochemical Pharmacology , 73 :1807 , 2007 |
| Abstract : Worek_2007_Biochem.Pharmacol_73_1807 |
| ESTHER : Worek_2007_Biochem.Pharmacol_73_1807 |
| PubMedSearch : Worek_2007_Biochem.Pharmacol_73_1807 |
| PubMedID: 17382909 |
| Title : Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes - Worek_2004_Biochem.Pharmacol_68_2237 |
| Author(s) : Worek F , Thiermann H , Szinicz L , Eyer P |
| Ref : Biochemical Pharmacology , 68 :2237 , 2004 |
| Abstract : Worek_2004_Biochem.Pharmacol_68_2237 |
| ESTHER : Worek_2004_Biochem.Pharmacol_68_2237 |
| PubMedSearch : Worek_2004_Biochem.Pharmacol_68_2237 |
| PubMedID: 15498514 |