DEAP-Phenothiazine
Close to ethopropazine, selective butyrylcholinesterase inhibitor
General
Type : Phenothiazine,Sulfur Compound
Chemical_Nomenclature : 10-(2-diethylaminopropionyl)phenothiazine hydrochloride
Canonical SMILES : CCN(CC)C(C)C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31.Cl
InChI : InChI=1S\/C19H22N2OS.ClH\/c1-4-20(5-2)14(3)19(22)21-15-10-6-8-12-17(15)23-18-13-9-7-11-16(18)21\;\/h6-14H,4-5H2,1-3H3\;1H
InChIKey : OMZUZRPGDRFFGQ-UHFFFAOYSA-N
Other name(s) : CHEMBL1782730,EU-0100351,SCHEMBL159034,C-007,10-(alpha-Diethylaminopropionyl)-phenothiazine hydrochloride
MW : 362.92
Formula : (C19H22N2)S.HCl
CAS_number :
PubChem : 11957509
UniChem : OMZUZRPGDRFFGQ-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (1)
| Title : Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease - Tasso_2011_Eur.J.Med.Chem_46_2170 |
| Author(s) : Tasso B , Catto M , Nicolotti O , Novelli F , Tonelli M , Giangreco I , Pisani L , Sparatore A , Boido V , Carotti A , Sparatore F |
| Ref : Eur Journal of Medicinal Chemistry , 46 :2170 , 2011 |
| Abstract : Tasso_2011_Eur.J.Med.Chem_46_2170 |
| ESTHER : Tasso_2011_Eur.J.Med.Chem_46_2170 |
| PubMedSearch : Tasso_2011_Eur.J.Med.Chem_46_2170 |
| PubMedID: 21459491 |