1. Home
  2. Inhibitor
  3. CD-Bzl

CD-Bzl

General

Type : Alkaloid,Derivative of Cinchonine,Quinoline,Natural_modified

Chemical_Nomenclature : (1-benzyl-5-ethenyl-1-azoniabicyclo[2.2.2]octan-2-yl)-quinolin-4-ylmethanol

Canonical SMILES : C=CC1C[N+]2(CCC1CC2C(C3=CC=NC4=CC=CC=C34)O)CC5=CC=CC=C5

InChI : InChI=1S\/C26H29N2O\/c1-2-20-18-28(17-19-8-4-3-5-9-19)15-13-21(20)16-25(28)26(29)23-12-14-27-24-11-7-6-10-22(23)24\/h2-12,14,20-21,25-26,29H,1,13,15-18H2\/q+1

InChIKey : RTHFVUKMXCJYPA-UHFFFAOYSA-N

Other name(s) : MCULE-9381258147,SCHEMBL13949293,MCULE-6617799642,1-Benzyl-2-(hydroxy(4-quinolinyl)methyl)-7-vinyl-1,4-ethanopiperidinium

MW : 465.4 || 385.5

Formula : C26H29BrN2O

CAS_number :

PubChem : 13095485, 3085408

UniChem : RTHFVUKMXCJYPA-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : CD-Bzl ligand of proteins in family: BCHE

Stucture :

Protein :

References (1)

Title : Design and evaluation of selective butyrylcholinesterase inhibitors based on Cinchona alkaloid scaffold - Bosak_2018_PLoS.One_13_e0205193
Author(s) : Bosak A , Ramic A , Smidlehner T , Hrenar T , Primozic I , Kovarik Z
Ref : PLoS ONE , 13 :e0205193 , 2018
Abstract : Bosak_2018_PLoS.One_13_e0205193
ESTHER : Bosak_2018_PLoS.One_13_e0205193
PubMedSearch : Bosak_2018_PLoS.One_13_e0205193
PubMedID: 30289893