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Inhibitor Report for: CB1R-ACHE-20

General
Type Multitarget, Cannabinoid-Receptor-ligand, Derivative of Tacrine, Imidazole, Carboxamide
Chemical_Nomenclature 2-(2-chlorophenyl)-1-(4-chlorophenyl)-5-ethyl-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]imidazole-4-carboxamide
Canonical SMILES CCC1=C(N=C(N1C2=CC=C(C=C2)Cl)C3=CC=CC=C3Cl)C(=O)NCCCCNC4=C5CCCCC5=NC6=CC=CC=C64
InChI InChI=1S/C35H35Cl2N5O/c1-2-31-33(41-34(25-11-3-6-14-28(25)37)42(31)24-19-17-23(36)18-20-24)35(43)39-22-10-9-21-38-32-26-12-4-7-15-29(26)40-30-16-8-5-13-27(30)32/h3-4,6-7,11-12,14-15,17-20H,2,5,8-10,13,16,21-22H2,1H3,(H,38,40)(H,39,43)
InChIKey STWYWUGMZLRNAY-UHFFFAOYSA-N
Other name(s) CHEMBL570159 ; SCHEMBL1336554 ; BDBM50303841 ; N-[4-(1,2,3,4-Tetrahydroacridin-9-ylamino)butyl]-2-(2-chlorophenyl)-1-(4-chlorophenyl)-5-ethyl-1H-imidazole-4-carboxamide
________________________________________________________________________________________________
MW|612.59
Formula|C35H35Cl2N5O
CAS_number|
PubChem|24825767
UniChem|STWYWUGMZLRNAY-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | CB1R-ACHE-20 ligand of proteins in family: ACHE

References:
Search PubMed for references concerning: CB1R-ACHE-20
    Title: Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonism
    Lange JH, Coolen HK, van der Neut MA, Borst AJ, Stork B, Verveer PC, Kruse CG
    Ref: Journal of Medicinal Chemistry, 53:1338, 2010 : PubMed