Anilofos

Anilofos poor inhibitor of cholinesterases IC50 AChE 25+/-10 BChE 8.6+/-0.7 microM

General

Type : Organophosphate,Sulfur Compound,Herbicide

Chemical_Nomenclature : N-(4-chlorophenyl)-2-dimethoxyphosphinothioylsulfanyl-N-propan-2-ylacetamide

Canonical SMILES : CC(C)N(C1=CC=C(C=C1)Cl)C(=O)CSP(=S)(OC)OC

InChI : InChI=1S\/C13H19ClNO3PS2\/c1-10(2)15(12-7-5-11(14)6-8-12)13(16)9-21-19(20,17-3)18-4\/h5-8,10H,9H2,1-4H3

InChIKey : NXQDBZGWYSEGFL-UHFFFAOYSA-N

Other name(s) : aniloguard,Arozin,Rico


MW : 367.9

Formula : C13H19ClNO3PS2

CAS_number : 64249-01-0

PubChem : 91687

UniChem : NXQDBZGWYSEGFL-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : Anilofos ligand of proteins in family: BCHE

Stucture :

Protein :

References (4)

Title : Selected herbicides screened for toxicity and analysed as inhibitors of both cholinesterases - Pehar_2023_Chem.Biol.Interact_14ChEPon_379_110506
Author(s) : Pehar V , Kolic D , Zandona A , Sinko G , Katalinic M , Stepanic V , Kovarik Z
Ref : Chemico-Biological Interactions , 379 :110506 , 2023
Abstract : Pehar_2023_Chem.Biol.Interact_14ChEPon_379_110506
ESTHER : Pehar_2023_Chem.Biol.Interact_14ChEPon_379_110506
PubMedSearch : Pehar_2023_Chem.Biol.Interact_14ChEPon_379_110506
PubMedID: 37141932

Title : Influence of malathion pretreatment on the toxicity of anilofos in male rats: a biochemical interaction study - Hazarika_2003_Toxicology_185_1
Author(s) : Hazarika A , Sarkar SN , Hajare S , Kataria M , Malik JK
Ref : Toxicology , 185 :1 , 2003
Abstract : Hazarika_2003_Toxicology_185_1
ESTHER : Hazarika_2003_Toxicology_185_1
PubMedSearch : Hazarika_2003_Toxicology_185_1
PubMedID: 12505439

Title : Subacute toxicity of anilofos, a new organophosphorus herbicide, in male rats: effect on some physical attributes and acetylcholinesterase activity - Hazarika_2001_Indian.J.Exp.Biol_39_1107
Author(s) : Hazarika A , Sarkar SN
Ref : Indian J Exp Biol , 39 :1107 , 2001
Abstract : Hazarika_2001_Indian.J.Exp.Biol_39_1107
ESTHER : Hazarika_2001_Indian.J.Exp.Biol_39_1107
PubMedSearch : Hazarika_2001_Indian.J.Exp.Biol_39_1107
PubMedID: 11906102

Title : Effect of isoproturon pretreatment on the biochemical toxicodynamics of anilofos in male rats - Hazarika_2001_Toxicology_165_87
Author(s) : Hazarika A , Sarkar SN
Ref : Toxicology , 165 :87 , 2001
Abstract : Hazarika_2001_Toxicology_165_87
ESTHER : Hazarika_2001_Toxicology_165_87
PubMedSearch : Hazarika_2001_Toxicology_165_87
PubMedID: 11522367