6RKY-K7K
When the OP reacts with an active site serine it can form a copper bipyridine complex creating a metal active site. The compound in PDB is ZK8
General
Type : Organophosphate,Pyridine,Metal ion chelator
Chemical_Nomenclature : 2-[3-[hexyl(methoxy)phosphoryl]oxypyridin-2-yl]pyridin-3-ol
Canonical SMILES : CCCCCCP(=O)(OC)OC1=C(N=CC=C1)C2=C(C=CC=N2)O
InChI : InChI=1S\/C17H23N2O4P\/c1-3-4-5-6-13-24(21,22-2)23-15-10-8-12-19-17(15)16-14(20)9-7-11-18-16\/h7-12,20H,3-6,13H2,1-2H3
InChIKey : DCWYQNLOUWKCTD-UHFFFAOYSA-N
Other name(s) : K7K,SID 404647527
MW : 350.3
Formula : C17H23N2O4P
CAS_number :
PubChem : 145706522
UniChem : DCWYQNLOUWKCTD-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : 6RKY-K7K ligand of proteins in family: Hormone-sensitive_lipase_like
Stucture : 6RKY Structure of ester-hydrolase EH1AB1 from the metagenome of lake Arreo complexed with a derivative of bipyridine phosphonate
Protein : 9bact-LAE6
References (1)
| Title : Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis - Alonso_2020_Nat.Catal_3_319 |
| Author(s) : Alonso S , Santiago G , Cea-Rama I , Fernandez-Lopez L , Coscolin C , Modregger J , Ressmann A , Martinez-Martinez M , Marrero H , Bargiela R , Pita M , Gonzalez-Alfonso JL , Briand M , Rojo D , Barbas C , Plou FJ , Golyshin PN , Shahgaldian P , Sanz-Aparicio J , Guallar V , Ferrer M |
| Ref : Nature Catalysis , 3 :319 , 2019 |
| Abstract : Alonso_2020_Nat.Catal_3_319 |
| ESTHER : Alonso_2020_Nat.Catal_3_319 |
| PubMedSearch : Alonso_2020_Nat.Catal_3_319 |
| PubMedID: |
| Gene_locus related to this paper: 9bact-LAE6 |