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Inhibitor Report for: 3-chloro-7-hydroxy-4-methylcoumarin

Coumaphos metabolite. Umbelliferone 7-hydroxycoumarins


General
Type Coumarin
Chemical_Nomenclature 3-chloro-7-Hydroxy-4-methylcoumarin
Canonical SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)O)Cl
InChI InChI=1S/C10H7ClO3/c1-5-7-3-2-6(12)4-8(7)14-10(13)9(5)11/h2-4,12H,1H3
InChIKey ODZHLDRQCZXQFQ-UHFFFAOYSA-N
Other name(s) Chlorferone ; Chlorferron ; 3-Chloro-4-methyl-7-hydroxycoumarin ; 7-Hydroxy-4-methyl-3-chlorocoumarin ; Coumarin, 3-chloro-7-hydroxy-4-methyl ; CHMC
________________________________________________________________________________________________
MW|210.6
Formula|C10H7ClO3
CAS_number|6174-86-3
PubChem|5355079
UniChem|ODZHLDRQCZXQFQ-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | 3-chloro-7-hydroxy-4-methylcoumarin ligand of proteins in family: BCHE, ACHE

References:
Search PubMed for references concerning: 3-chloro-7-hydroxy-4-methylcoumarin
    Title: Reversible inhibition of acetylcholinesterase and butyrylcholinesterase by 4,4'-bipyridine and by a coumarin derivative
    Simeon-Rudolf V, Kovarik Z, Radic Z, Reiner E
    Ref: Chemico-Biological Interactions, 119-120:119, 1999 : PubMed

            

    Title: Biotransformation and disposition of the coumaphos metabolite 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin in rats
    Malik JK, Lay JP, Klein W, Korte F
    Ref: Archives of Toxicology, 48:51, 1981 : PubMed