Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: 2-allyl-4-oxocyclobutyl-4-methylbenzenesulfonamide

General
Type Sulfur Compound, Sulfonamide
Chemical_Nomenclature N-((1R,2S)-2-allyl-4-oxocyclobutyl)-4-methylbenzenesulfonamide
Canonical SMILES Cc1ccc(cc1)S(=O)(=O)N[C@H]1[C@@H](O)C[C@@H]1CC=C
InChI InChI=1S/C14H19NO3S/c1-3-4-11-9-13(16)14(11)15-19(17,18)12-7-5-10(2)6-8-12/h3,5-8,11,13-16H,1,4,9H2,2H3/t11-,13-,14+/m0/s1
InChIKey KFIWUGSQQLTLIY-FPMFFAJLSA-N
Other name(s) 4-methyl-N-[(1R,2S,4S)-2-oxidanyl-4-prop-2-enyl-cyclobutyl]benzenesulfonamide ; 0S1 ; ZINC000098207858
________________________________________________________________________________________________
MW|281.37
Formula|C14H19NO3S
CAS_number|
PubChem|137347887
UniChem|KFIWUGSQQLTLIY-FPMFFAJLSA-N
IUPHAR|
Wikipedia|

Target
Families | 2-allyl-4-oxocyclobutyl-4-methylbenzenesulfonamide ligand of proteins in family: LYsophospholipase_carboxylesterase
Stucture | 1 structure: 4F21: Crystal structure of carboxylesterase/phospholipase family protein from Francisella tularensis
Protein | fratt-q5ni32

References:
Search PubMed for references concerning: 2-allyl-4-oxocyclobutyl-4-methylbenzenesulfonamide
    Title: Large-scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis
    Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I and Johnson RJ <6 more author(s)>
    Ref: Journal of Biological Chemistry, 288:10522, 2013 : PubMed