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Inhibitor Report for: 19,20-EDP-product

product of hydrolysis of the epoxide 19,20-ED


General
Type Fatty acid
Chemical_Nomenclature (19S,20R)-19,20-dihydroxydocosa-4,7,10,13,16-pentaenoic acid
Canonical SMILES CCC(C(CC=CCC=CCC=CCC=CCC=CCCC(=O)O)O)O
InChI InChI=1S/C22H34O4/c1-2-20(23)21(24)18-16-14-12-10-8-6-4-3-5-7-9-11-13-15-17-19-22(25)26/h3-4,7-10,13-16,20-21,23-24H,2,5-6,11-12,17-19H2,1H3,(H,25,26)/t20-,21+/m1/s1
InChIKey FFXKPSNQCPNORO-KVZKRMIJSA-N FFXKPSNQCPNORO-RTWAWAEBSA-N
Other name(s) 7HW ; (+/-)19,20-DiHDPA ; CTK8F1523
________________________________________________________________________________________________
MW|362.50
Formula|C22H34O4
CAS_number|
PubChem|57369969
UniChem|FFXKPSNQCPNORO-KVZKRMIJSA-N, FFXKPSNQCPNORO-RTWAWAEBSA-N
IUPHAR|
Wikipedia|

Target
Families | 19,20-EDP-product ligand of proteins in family: CFTR-inhibitory-factor_Cif
Stucture | 1 structure: 5TNF: Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 19,20-EDP (epoxy-docosapentaenoic acid)
Protein | pseae-PA2934

References:
Search PubMed for references concerning: 19,20-EDP-product
    Title: Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase
    Hvorecny KL, Bahl CD, Kitamura S, Lee KSS, Hammock BD, Morisseau C, Madden DR
    Ref: Structure, 25:697, 2017 : PubMed