WWL229
General
Type : pNP,Carbamate,Piperidine
Chemical_Nomenclature : (4-nitrophenyl) 2-(3-methoxypropyl)piperidine-1-carboxylate
Canonical SMILES : COCCCC1CCCCN1C(=O)OC2=CC=C(C=C2)[N+](=O)[O-]
InChI : InChI=1S\/C16H22N2O5\/c1-22-12-4-6-13-5-2-3-11-17(13)16(19)23-15-9-7-14(8-10-15)18(20)21\/h7-10,13H,2-6,11-12H2,1H3
InChIKey : XVBRVSAGMWRVCK-UHFFFAOYSA-N
Other name(s) : Wwl229,4-Nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate,AOB2408,SYN5249,MolPort-039-138-796
MW : 322.36
Formula : C16H22N2O5
CAS_number : 1338575-28-2
PubChem : 72183487
UniChem : XVBRVSAGMWRVCK-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : WWL229 ligand of proteins in family: Carb_B_Chordata
Stucture :
Protein : human-CES3 || mouse-Ces1d
References (2)
| Title : A Unique Role of Carboxylesterase 3 (Ces3) in beta-Adrenergic Signaling-Stimulated Thermogenesis - Yang_2019_Diabetes_68_1178 |
| Author(s) : Yang L , Li X , Tang H , Gao Z , Zhang K , Sun K |
| Ref : Diabetes , 68 :1178 , 2019 |
| Abstract : Yang_2019_Diabetes_68_1178 |
| ESTHER : Yang_2019_Diabetes_68_1178 |
| PubMedSearch : Yang_2019_Diabetes_68_1178 |
| PubMedID: 30862682 |
| Gene_locus related to this paper: human-CES3 , mouse-Ces1d |
| Title : Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes - Dominguez_2014_Nat.Chem.Biol_10_113 |
| Author(s) : Dominguez E , Galmozzi A , Chang JW , Hsu KL , Pawlak J , Li W , Godio C , Thomas J , Partida D , Niessen S , O'Brien PE , Russell AP , Watt MJ , Nomura DK , Cravatt BF , Saez E |
| Ref : Nat Chemical Biology , 10 :113 , 2014 |
| Abstract : Dominguez_2014_Nat.Chem.Biol_10_113 |
| ESTHER : Dominguez_2014_Nat.Chem.Biol_10_113 |
| PubMedSearch : Dominguez_2014_Nat.Chem.Biol_10_113 |
| PubMedID: 24362705 |
| Gene_locus related to this paper: human-CES3 , mouse-Ces1d |