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TerritremC

Mycotoxin purified from culture of fungus Aspergillus terreus 23-1 growing on rice

General

Type : Natural,Meroterpenoid

Chemical_Nomenclature : 4H,11H-Naphtho(2,1-b)pyrano(3,4-e)pyran-1,11(5H)-dione, 4a,6,6a,12,12a,12b-hexahydro-4a,12a-dihydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-4,4,6a,12b-tetramethyl-, (4aR-(4a-alpha,6a-beta,12a-alpha,12b-beta))-

Canonical SMILES : CC1(C=CC(=O)C2(C1(CCC3(C2(CC4=C(O3)C=C(OC4=O)C5=CC(=C(C(=C5)OC)O)OC)O)C)O)C)C

InChI : InChI=1S\/C28H32O9\/c1-24(2)8-7-21(29)26(4)27(24,32)10-9-25(3)28(26,33)14-16-18(37-25)13-17(36-23(16)31)15-11-19(34-5)22(30)20(12-15)35-6\/h7-8,11-13,30,32-33H,9-10,14H2,1-6H3\/t25-,26+,27-,28-\/m1\/s1

InChIKey : FTTNXWIFPFEOQT-JUDWXZBOSA-N

Other name(s) :

MW : 512.20

Formula : C28H32O9

CAS_number : 89020-33-7

PubChem : 160306

UniChem : FTTNXWIFPFEOQT-JUDWXZBOSA-N

IUPHAR :

Wikipedia :

Target

Families : TerritremC ligand of proteins in family: ACHE

Stucture :

Protein :

References (4)

Title : Territrem: neurotoxicity and biotransformation -
Author(s) : Ling KH
Ref : Journal of Toxicological Sciences , 2 :189 , 1998
PubMedID: 9760461

Title : NMR assignments of territrems A, B, and C and the structure of MB2, the major metabolite of territrem B by rat liver microsomal fraction - Lee_1992_J.Nat.Prod_55_251
Author(s) : Lee SS , Peng FC , Chiou CM , Ling KH
Ref : Journal of Natural Products , 55 :251 , 1992
Abstract : Lee_1992_J.Nat.Prod_55_251
ESTHER : Lee_1992_J.Nat.Prod_55_251
PubMedSearch : Lee_1992_J.Nat.Prod_55_251
PubMedID: 1624944

Title : Biotransformation of territrems by S9 fraction from rat liver - Ling_1991_Drug.Metab.Dispos_19_587
Author(s) : Ling KH , Chiou CM , Tseng YL
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 19 :587 , 1991
Abstract : Ling_1991_Drug.Metab.Dispos_19_587
ESTHER : Ling_1991_Drug.Metab.Dispos_19_587
PubMedSearch : Ling_1991_Drug.Metab.Dispos_19_587
PubMedID: 1680623

Title : Isolation, chemical structure, acute toxicity, and some physicochemical properties of territrem C from Aspergillus terreus - Ling_1984_Appl.Environ.Microbiol_47_98
Author(s) : Ling KH , Liou HH , Yang CM , Yang CK
Ref : Applied Environmental Microbiology , 47 :98 , 1984
Abstract : Ling_1984_Appl.Environ.Microbiol_47_98
ESTHER : Ling_1984_Appl.Environ.Microbiol_47_98
PubMedSearch : Ling_1984_Appl.Environ.Microbiol_47_98
PubMedID: 6546485