Nu-1250

General

Type : Carbamate,Trimethylammonium

Chemical_Nomenclature : N-p-chlorophenyl-N-methylcarbamate of m-hydroxyphenyltrimethylammonium bromide

Canonical SMILES : C1=C(C=CC=C1OC(N(C)C2=CC=C(C=C2)Cl)=O)[N+](C)(C)C.[Br-]

InChI : InChI=1S\/C17H20ClN2O2.BrH\/c1-19(14-10-8-13(18)9-11-14)17(21)22-16-7-5-6-15(12-16)20(2,3)4\;\/h5-12H,1-4H3\;1H\/q+1\;\/p-1

InChIKey : PCQGALCVXJWHNH-UHFFFAOYSA-M

Other name(s) :


MW : 399,71

Formula : C17H20N2O2ClBr

CAS_number :

PubChem :

UniChem : PCQGALCVXJWHNH-UHFFFAOYSA-M

IUPHAR :

Wikipedia :

Target

Families : Nu-1250 ligand of proteins in family: ACHE

Stucture :

Protein :

References (3)

Title : Anticholinesterases in the heart-lung preparation -
Author(s) : Burn JH , Walker JM
Ref : Journal de Physiologie , 124 :489 , 1954
PubMedID: 13175193

Title : [Anticholinesteratic and pharmacological effects of the bromide of N-P-Chlorophenyl-methylcarbamate of M-Hydroxyphenyltrimethylammonium (NU 1250)] -
Author(s) : Casier H , De Vleeschhouwer GR
Ref : Archives Internationales de Pharmacodynamie et de Therapie , 90 :412 , 1952
PubMedID: 12986938

Title : Tubocurarine antagonism and inhibition of cholinesterases -
Author(s) : Blaschko H , Bulbring E , Chou TC
Ref : British Journal of Pharmacology , 4 :29 , 1949
PubMedID: 18113150