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Inhibitor Report for: Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate

inhibitor of butyrylcholinesterase, inhibitor of catalytic antibodies


General
Type Organophosphate, pNP, Sulfur Compound, Biotin derivative
Chemical_Nomenclature Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate
Canonical SMILES CO[P](=O)(CC1=CC=C(C=C1)NC(=O)CCCCC2C3C(CS2)NC(=O)N3)CC4=CC=C(C=C4)[N+](=O)[O-]
InChI InChI=1S/C25H31N4O6PS/c1-35-36(34,15-18-8-12-20(13-9-18)29(32)33)14-17-6-10-19(11-7-17)26-23(30)5-3-2-4-22-24-21(16-37-22)27-25(31)28-24/h6-13,21-22,24H,2-5,14-16H2,1H3,(H,26,30)(H2,27,28,31)
InChIKey HYVZBUFOKWXQIP-UHFFFAOYSA-N
Other name(s)
________________________________________________________________________________________________
MW|546.58
Formula|C25H31N4O6PS
CAS_number|
PubChem|
UniChem|HYVZBUFOKWXQIP-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate ligand of proteins in family: BCHE

References:
Search PubMed for references concerning: Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate
    Title: Enzyme mimicry by the antiidiotypic antibody approach
    Kolesnikov AV, Kozyr AV, Alexandrova ES, Koralewski F, Demin AV, Titov MI, Avalle B, Tramontano A, Paul S and Friboulet A <2 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 97:13526, 2000 : PubMed

            

    Title: Inhibition and labeling of enzymes and abzymes by phosphonate diesters
    Tramontano A, Ivanov B, Gololobov G, Paul S
    Ref: Appl Biochem Biotechnol, 83:233, 2000 : PubMed