MPOX

Metoxadiazone (the 2 methoxyphenyl) also called MPOX

General

Type : Oxadiazolone,Oxadiazol,Lipase inhibitor

Chemical_Nomenclature : 5-methoxy-3-phenyl-1,3,4-oxadiazol-2-one

Canonical SMILES : COC1=NN(C(=O)O1)C2=CC=CC=C2

InChI : InChI=1S\/C9H8N2O3\/c1-13-8-10-11(9(12)14-8)7-5-3-2-4-6-7\/h2-6H,1H3

InChIKey : RBPWSXBBSLDLJS-UHFFFAOYSA-N

Other name(s) : 5-Methoxy-3-phenyl-1,3,4-oxadiazol-2(3H)-one,CHEMBL2171699,SCHEMBL11620781


MW : 192

Formula : C9H8N2O3

CAS_number :

PubChem : 20366964

UniChem : RBPWSXBBSLDLJS-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : MPOX ligand of proteins in family: Acidic_Lipase

Stucture :

Protein :

References (1)

Title : Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones. - Point_2012_Eur.J.Med.Chem_58_452
Author(s) : Point V , Pavan Kumar KV , Marc S , Delorme V , Parsiegla G , Amara S , Carriere F , Buono G , Fotiadu F , Canaan S , Leclaire J , Cavalier JF
Ref : Eur Journal of Medicinal Chemistry , 58 :452 , 2012
Abstract : Point_2012_Eur.J.Med.Chem_58_452
ESTHER : Point_2012_Eur.J.Med.Chem_58_452
PubMedSearch : Point_2012_Eur.J.Med.Chem_58_452
PubMedID: 23153815
Gene_locus related to this paper: canfa-1lipg , cavpo-2plrp , human-CEL , human-PNLIP , human-PNLIPRP2 , pig-1plip