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Inhibitor Report for: Lycocasuarine-C

IC50 AChE 0.24 +/-0.03 BChE 1.82 +/- 0.12 microM


General
Type Derivative of Huperzine, Natural
Chemical_Nomenclature
Canonical SMILES C1(NC2=C(C=C1)[C@]34[C@@H](C(C2)C=C(C3)C)C(C([N+]4(C)[O-])=O)CO)=O
InChI InChI=1S/C17H20N2O4/c1-9-5-10-6-13-12(3-4-14(21)18-13)17(7-9)15(10)11(8-20)16(22)19(17,2)23/h3-5,10-11,15,20H,6-8H
InChIKey DVCLJMAFRIENKG-XOCRXOJUSA-N
Other name(s) lycocasuarine C
________________________________________________________________________________________________
MW|316.35
Formula|C17H20N2O4
CAS_number|
PubChem|
UniChem|DVCLJMAFRIENKG-XOCRXOJUSA-N
IUPHAR|
Wikipedia|

Target
Families | Lycocasuarine-C ligand of proteins in family: ACHE
Protein | human-ACHE

References:
Search PubMed for references concerning: Lycocasuarine-C
    Title: Lycodine type alkaloids from Lycopodiastrum casuarinoides with cytotoxic and cholinesterase inhibitory activities
    Qu SM, Shan BH, Wang HT, Wang S
    Ref: Fitoterapia, 131:86, 2018 : PubMed