Disulfoton

General

Type : Acaricide,Insecticide,Organophosphate,Sulfur Compound,Organothiophosphate

Chemical_Nomenclature : Phosphorodithioic acid O,O-diethyl S-[2-(ethylthio)ethyl] ester

Canonical SMILES : CCOP(=S)(OCC)SCCSCC

InChI : InChI=1S\/C8H19O2PS3\/c1-4-9-11(12,10-5-2)14-8-7-13-6-3\/h4-8H2,1-3H3

InChIKey : DOFZAZXDOSGAJZ-UHFFFAOYSA-N

Other name(s) : Dithiodemeton,Dithiosystox,Thiodemeton,Solvigran,Glebofos,Solvirex,Dution,Frumin,Ethyl thiometon,dithiosystox Bay S276,Disyston,Disystox,Frumin AL,and Solvirex


MW : 274.40

Formula : C8H19O2PS3

CAS_number : 298-04-4

PubChem : 3118

UniChem : DOFZAZXDOSGAJZ-UHFFFAOYSA-N

IUPHAR :

Wikipedia : Disulfoton

Target

Families : Disulfoton ligand of proteins in family: ACHE

Stucture :

Protein :

References (19)

Title : S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2 - Henderson_2004_Biochem.Pharmacol_68_959
Author(s) : Henderson MC , Krueger SK , Siddens LK , Stevens JF , Williams DE
Ref : Biochemical Pharmacology , 68 :959 , 2004
Abstract : Henderson_2004_Biochem.Pharmacol_68_959
ESTHER : Henderson_2004_Biochem.Pharmacol_68_959
PubMedSearch : Henderson_2004_Biochem.Pharmacol_68_959
PubMedID: 15294458

Title : Empirical and modeling evidence of regional atmospheric transport of current-use pesticides - Muir_2004_Environ.Toxicol.Chem_23_2421
Author(s) : Muir DC , Teixeira C , Wania F
Ref : Environ Toxicol Chem , 23 :2421 , 2004
Abstract : Muir_2004_Environ.Toxicol.Chem_23_2421
ESTHER : Muir_2004_Environ.Toxicol.Chem_23_2421
PubMedSearch : Muir_2004_Environ.Toxicol.Chem_23_2421
PubMedID: 15511103

Title : Damage loss assessment and control of the cereal leaf beetle (Coleoptera: Chrysomelidae) in winter wheat - Buntin_2004_J.Econ.Entomol_97_374
Author(s) : Buntin GD , Flanders KL , Slaughter RW , DeLamar ZD
Ref : J Econ Entomol , 97 :374 , 2004
Abstract : Buntin_2004_J.Econ.Entomol_97_374
ESTHER : Buntin_2004_J.Econ.Entomol_97_374
PubMedSearch : Buntin_2004_J.Econ.Entomol_97_374
PubMedID: 15154458

Title : Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides - Smulders_2004_Toxicol.Sci_82_545
Author(s) : Smulders CJ , Bueters TJ , Vailati S , van Kleef RG , Vijverberg HP
Ref : Toxicol Sci , 82 :545 , 2004
Abstract : Smulders_2004_Toxicol.Sci_82_545
ESTHER : Smulders_2004_Toxicol.Sci_82_545
PubMedSearch : Smulders_2004_Toxicol.Sci_82_545
PubMedID: 15342957

Title : Insecticide use and organophosphate resistance in the coffee leaf miner Leucoptera coffeella (Lepidoptera: Lyonetiidae) - Fragoso_2002_Bull.Entomol.Res_92_203
Author(s) : Fragoso DB , Guedes RN , Picanco MC , Zambolim L
Ref : Bull Entomol Res , 92 :203 , 2002
Abstract : Fragoso_2002_Bull.Entomol.Res_92_203
ESTHER : Fragoso_2002_Bull.Entomol.Res_92_203
PubMedSearch : Fragoso_2002_Bull.Entomol.Res_92_203
PubMedID: 12088537

Title : A small-volume bioassay for quantification of the esterase inhibiting potency of mixtures of organophosphate and carbamate insecticides in rainwater: development and optimization - Hamers_2000_Toxicol.Sci_58_60
Author(s) : Hamers T , Molin KR , Koeman JH , Murk AJ
Ref : Toxicol Sci , 58 :60 , 2000
Abstract : Hamers_2000_Toxicol.Sci_58_60
ESTHER : Hamers_2000_Toxicol.Sci_58_60
PubMedSearch : Hamers_2000_Toxicol.Sci_58_60
PubMedID: 11053541

Title : Changes in mRNA expression levels of synaptic- and target tissue-specific proteins after organophosphate exposure - Matsuda_2000_Leg.Med.(Tokyo)_2_55
Author(s) : Matsuda H , Seo Y , Kakizaki E , Takahama K
Ref : Leg Med (Tokyo) , 2 :55 , 2000
Abstract : Matsuda_2000_Leg.Med.(Tokyo)_2_55
ESTHER : Matsuda_2000_Leg.Med.(Tokyo)_2_55
PubMedSearch : Matsuda_2000_Leg.Med.(Tokyo)_2_55
PubMedID: 12935443

Title : Organophosphate Resistance Mediated by Alterations of Acetylcholinesterase in a Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae) - Zhu_2000_Pestic.Biochem.Physiol_68_138
Author(s) : Zhu KY , Gao JR , Starkey SR
Ref : Pesticide Biochemistry and Physiology , 68 :138 , 2000
Abstract : Zhu_2000_Pestic.Biochem.Physiol_68_138
ESTHER : Zhu_2000_Pestic.Biochem.Physiol_68_138
PubMedSearch : Zhu_2000_Pestic.Biochem.Physiol_68_138
PubMedID:

Title : Absence of neurovisual effects due to tissue and blood cholinesterase depression in a chronic disulfoton feeding study in dogs - Jones_1999_Toxicol.Lett_106_181
Author(s) : Jones RD , Hastings TF , Landes AM
Ref : Toxicol Lett , 106 :181 , 1999
Abstract : Jones_1999_Toxicol.Lett_106_181
ESTHER : Jones_1999_Toxicol.Lett_106_181
PubMedSearch : Jones_1999_Toxicol.Lett_106_181
PubMedID: 10403662

Title : Preparation of some toxic metabolites of disulfoton, phorate, and terbufos, their separation by thin-layer chromatography and confirmation by electron impact mass spectrometry - Simonovska_1997_J.AOAC.Int_80_688
Author(s) : Simonovska B
Ref : Journal of AOAC International , 80 :688 , 1997
Abstract : Simonovska_1997_J.AOAC.Int_80_688
ESTHER : Simonovska_1997_J.AOAC.Int_80_688
PubMedSearch : Simonovska_1997_J.AOAC.Int_80_688
PubMedID: 9170663

Title : Subchronic neurotoxicity screening studies with six organophosphate insecticides: an assessment of behavior and morphology relative to cholinesterase inhibition - Sheets_1997_Fundam.Appl.Toxicol_35_101
Author(s) : Sheets LP , Hamilton BF , Sangha GK , Thyssen JH
Ref : Fundamental & Applied Toxicology , 35 :101 , 1997
Abstract : Sheets_1997_Fundam.Appl.Toxicol_35_101
ESTHER : Sheets_1997_Fundam.Appl.Toxicol_35_101
PubMedSearch : Sheets_1997_Fundam.Appl.Toxicol_35_101
PubMedID: 9024678

Title : Sublethal effects of prolonged exposure to disulfoton in rainbow trout (Oncorhynchus mykiss): cytological alterations in the liver by a potent acetylcholine esterase inhibitor - Arnold_1996_Ecotoxicol.Environ.Saf_34_43
Author(s) : Arnold H , Pluta HJ , Braunbeck T
Ref : Ecotoxicology & Environmental Safety , 34 :43 , 1996
Abstract : Arnold_1996_Ecotoxicol.Environ.Saf_34_43
ESTHER : Arnold_1996_Ecotoxicol.Environ.Saf_34_43
PubMedSearch : Arnold_1996_Ecotoxicol.Environ.Saf_34_43
PubMedID: 8793319

Title : Effects of organophosphate exposure on muscarinic acetylcholine receptor subtype mRNA levels in the adult rat - Yagle_1996_Neurotoxicol_17_523
Author(s) : Yagle K , Costa LG
Ref : Neurotoxicology , 17 :523 , 1996
Abstract : Yagle_1996_Neurotoxicol_17_523
ESTHER : Yagle_1996_Neurotoxicol_17_523
PubMedSearch : Yagle_1996_Neurotoxicol_17_523
PubMedID: 8856746

Title : Acute organophosphate poisoning after disulfoton ingestion - Futagami_1995_J.Toxicol.Clin.Toxicol_33_151
Author(s) : Futagami K , Otsubo K , Nakao Y , Aoyama T , Iimori E , Urakami S , Ide M , Oishi R
Ref : Journal of Toxicology Clinical Toxicology , 33 :151 , 1995
Abstract : Futagami_1995_J.Toxicol.Clin.Toxicol_33_151
ESTHER : Futagami_1995_J.Toxicol.Clin.Toxicol_33_151
PubMedSearch : Futagami_1995_J.Toxicol.Clin.Toxicol_33_151
PubMedID: 7897754

Title : Correlation of the anticholinesterase activity of a series of organophosphates with their ability to compete with agonist binding to muscarinic receptors - Ward_1993_Toxicol.Appl.Pharmacol_122_300
Author(s) : Ward TR , Ferris DJ , Tilson HA , Mundy WR
Ref : Toxicology & Applied Pharmacology , 122 :300 , 1993
Abstract : Ward_1993_Toxicol.Appl.Pharmacol_122_300
ESTHER : Ward_1993_Toxicol.Appl.Pharmacol_122_300
PubMedSearch : Ward_1993_Toxicol.Appl.Pharmacol_122_300
PubMedID: 8212012

Title : Modulation of muscarinic receptors and acetylcholinesterase activity in lymphocytes and in brain areas following repeated organophosphate exposure in rats - Fitzgerald_1993_Fundam.Appl.Toxicol_20_210
Author(s) : Fitzgerald BB , Costa LG
Ref : Fundamental & Applied Toxicology , 20 :210 , 1993
Abstract : Fitzgerald_1993_Fundam.Appl.Toxicol_20_210
ESTHER : Fitzgerald_1993_Fundam.Appl.Toxicol_20_210
PubMedSearch : Fitzgerald_1993_Fundam.Appl.Toxicol_20_210
PubMedID: 8449393

Title : Brain cholinesterase inhibition in songbirds from pecan groves sprayed with phosalone and disulfoton - White_1990_J.Wildl.Dis_26_103
Author(s) : White DH , Seginak JT
Ref : J Wildl Dis , 26 :103 , 1990
Abstract : White_1990_J.Wildl.Dis_26_103
ESTHER : White_1990_J.Wildl.Dis_26_103
PubMedSearch : White_1990_J.Wildl.Dis_26_103
PubMedID: 2304190

Title : Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates - McDonald_1988_Toxicol.Lett_40_42
Author(s) : McDonald BE , Costa LG , Murphy SD
Ref : Toxicol Lett , 40 :42 , 1988
Abstract : McDonald_1988_Toxicol.Lett_40_42
ESTHER : McDonald_1988_Toxicol.Lett_40_42
PubMedSearch : McDonald_1988_Toxicol.Lett_40_42
PubMedID: 3341049

Title : Simplified cleanup and gas chromatographic determination of organophosphorus pesticides in crops - Sasaki_1987_J.Assoc.Off.Anal.Chem_70_460
Author(s) : Sasaki K , Suzuki T , Saito Y
Ref : J Assoc Off Analytical Chemistry , 70 :460 , 1987
Abstract : Sasaki_1987_J.Assoc.Off.Anal.Chem_70_460
ESTHER : Sasaki_1987_J.Assoc.Off.Anal.Chem_70_460
PubMedSearch : Sasaki_1987_J.Assoc.Off.Anal.Chem_70_460
PubMedID: 3610958