DEPQ

fluorescent leaving group is 7HMC (7-hydroxy-4-methylcoumarin)

General

Type : Organophosphate,Quinoline

Chemical_Nomenclature : diethyl (1-methylquinolin-1-ium-7-yl) phosphate

Canonical SMILES : CCOP(=O)(OCC)OC1=CC2=C(C=CC=[N+]2C)C=C1

InChI : InChI=1S\/C14H19NO4P\/c1-4-17-20(16,18-5-2)19-13-9-8-12-7-6-10-15(3)14(12)11-13\/h6-11H,4-5H2,1-3H3\/q+1

InChIKey : CVKRJKJYOIKAHS-UHFFFAOYSA-N

Other name(s) : 7-[(diethoxyphosphoryl)oxy]-1-methylquinolinium iodide


MW : 296.28

Formula : C14H19NO4P+

CAS_number :

PubChem : 10402289

UniChem : CVKRJKJYOIKAHS-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : DEPQ ligand of proteins in family: ACHE

Stucture :

Protein :

References (2)

Title : Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime - Luo_1999_Chem.Biol.Interact_119-120_129
Author(s) : Luo C , Saxena A , Ashani Y , Leader H , Radic Z , Taylor P , Doctor BP
Ref : Chemico-Biological Interactions , 119-120 :129 , 1999
Abstract : Luo_1999_Chem.Biol.Interact_119-120_129
ESTHER : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedSearch : Luo_1999_Chem.Biol.Interact_119-120_129
PubMedID: 10421446

Title : Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands. Distinct effects of propidium and fasciculin - Mallender_1999_J.Biol.Chem_274_8491
Author(s) : Mallender WD , Szegletes T , Rosenberry TL
Ref : Journal of Biological Chemistry , 274 :8491 , 1999
Abstract : Mallender_1999_J.Biol.Chem_274_8491
ESTHER : Mallender_1999_J.Biol.Chem_274_8491
PubMedSearch : Mallender_1999_J.Biol.Chem_274_8491
PubMedID: 10085081