Cpd14-BChEin-5-HT6
h5-HT6R Ki (microM) 0.022+/-0.002; hAChE IC50 (microM) 0.930+/-0.035; hBuChE IC50 (microM)0.016+/-0.001
General
Type : Multitarget,5-HT-receptor-ligand,Sulfur Compound,Indole,Alkyl linked bis-ligand
Chemical_Nomenclature :
Canonical SMILES : C1(=CC=CC2=C1C=C[N]2[S](=O)(=O)C3=CC=CC=C3)OCCNCCCC4CCN(CC4)CC5=CC=CC=C5
InChI : InChI=1S\/C31H37N3O3S\/c35-38(36,28-12-5-2-6-13-28)34-23-18-29-30(34)14-7-15-31(29)37-24-20-32-19-8-11-26-16-21-33(22-17-26)25-27-9-3-1-4-10-27\/h1-7,9-10,12-15,18,23,26,32H,8,11,16-17,19-22,24-25H2
InChIKey : CKCCUHPTJCNASI-UHFFFAOYSA-N
Other name(s) :
MW : 531.71
Formula : C31H37N3O3S
CAS_number :
PubChem :
UniChem : CKCCUHPTJCNASI-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (1)
| Title : Serotonin 5-HT(6) Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity-Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease - Wieckowski_2022_Int.J.Mol.Sci_23_9443 |
| Author(s) : Wieckowski K , Szalaj N , Gryzlo B , Wichur T , Goral I , Slugocka E , Sniecikowska J , Latacz G , Siwek A , Godyn J , Bucki A , Kolaczkowski M , Wieckowska A |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : Wieckowski_2022_Int.J.Mol.Sci_23_9443 |
| ESTHER : Wieckowski_2022_Int.J.Mol.Sci_23_9443 |
| PubMedSearch : Wieckowski_2022_Int.J.Mol.Sci_23_9443 |
| PubMedID: 36012707 |