CGA-134-736
Natural organophosphate inhibitor of Acetylcholinesterase isolated from cultures of Streptomyces antibioticus strain DSM 1951. Compound very close to Cyclophostin described by Kurokawa 1993 J.Antibiot.(Tokyo) 46 1315. IC50 for AChE of 500 nM
General
Type : Organophosphate,Cyclic OP,Natural
Chemical_Nomenclature : methyl substituted furo-dioxaphosphepin
Canonical SMILES : CC2=C1COC[C@@H]1CO[P@](=O)(O2)OC
InChI : InChI=1S\/C8H13O5P\/c1-6-8-5-11-3-7(8)4-12-14(9,10-2)13-6\/h7H,3-5H2,1-2H3\/t7-,14-\/m1\/s1
InChIKey : YWJGECVANWGATG-NXSYQRQQSA-N
Other name(s) : ZINC13433299
MW : 220.16
Formula : C8H13O5P
CAS_number :
PubChem :
UniChem : YWJGECVANWGATG-NXSYQRQQSA-N
IUPHAR :
Wikipedia :
Target
References (1)
| Title : Insecticidal organophosphates: Nature made them first - Neumann_1987_Experientia_43_1235 |
| Author(s) : Neumann R , Peter HH |
| Ref : Experientia , 43 :1235-1237 , 1987 |
| Abstract : Neumann_1987_Experientia_43_1235 |
| ESTHER : Neumann_1987_Experientia_43_1235 |
| PubMedSearch : Neumann_1987_Experientia_43_1235 |
| PubMedID: |