Methylchlorpyrifos

Chlorpyrifos-methyl-oxon is the oxon form of Methylchlorpyrifos . Fospirate: L. cuprina AChE, IC50 [nM] 0.5 +/- 0.06 ; Human AChE, IC50 [nM] 1521 +/- 229

General

Type : Trichloro, Organophosphate, Sulfur Compound, Organothiophosphate, Insecticide, Organochlorine

Chemical_Nomenclature : O,O-Dimethyl-O-(3,5,6-trichloro-2-pyridyl)phosphorothioate

Canonical SMILES : COP(=S)(OC)OC1=NC(=C(C=C1Cl)Cl)Cl

InChI : InChI=1S\/C7H7Cl3NO3PS\/c1-12-15(16,13-2)14-7-5(9)3-4(8)6(10)11-7\/h3H,1-2H3

InChIKey : HRBKVYFZANMGRE-UHFFFAOYSA-N

Other name(s) : dimethoxy-sulfanylidene-(3,5,6-trichloropyridin-2-yl)oxy-phosphorane  ||  Noltran  ||  Zertell  ||  Reldan  ||  Dursban methyl  ||  Methyl dursban  ||  Trichlormethylfos  ||  Chlormethylfos  ||  Fospirate  ||  Cooper graincote  ||  Chlorpyrifos-methyl  ||  Dowco 214


MW : 322.53

Formula : C7H7Cl3NO3PS

CAS_number : 5598-13-0

PubChem : 21803

UniChem : HRBKVYFZANMGRE-UHFFFAOYSA-N

Target

Families : Methylchlorpyrifos ligand of proteins in family
ACHE

References (4)

Title : The characterization of Lucilia cuprina acetylcholinesterase as a drug target, and the identification of novel inhibitors by high throughput screening - Ilg_2011_Insect.Biochem.Mol.Biol_41_470
Author(s) : Ilg T , Cramer J , Lutz J , Noack S , Schmitt H , Williams H , Newton T
Ref : Insect Biochemistry & Molecular Biology , 41 :470 , 2011
Abstract :
PubMedSearch : Ilg_2011_Insect.Biochem.Mol.Biol_41_470
PubMedID: 21530657

Title : Organohalogen and organophosphorus pesticides in mixed feed rations: findings from FDA's domestic surveillance during fiscal years 1989-1994 - Lovell_1996_J.AOAC.Int_79_544
Author(s) : Lovell RA , McChesney DG , Price WD
Ref : Journal of AOAC International , 79 :544 , 1996
Abstract :
PubMedSearch : Lovell_1996_J.AOAC.Int_79_544
PubMedID: 8920144

Title : Acute toxicity of several organophosphorous insecticides and protection by cholinergic antagonists and 2-PAM on Artemia salina larvae - Sanchez-Fortun_1996_Arch.Environ.Contam.Toxicol_31_391
Author(s) : Sanchez-Fortun S , Sanz F , Barahona MV
Ref : Archives of Environmental Contamination & Toxicology , 31 :391 , 1996
Abstract :
PubMedSearch : Sanchez-Fortun_1996_Arch.Environ.Contam.Toxicol_31_391
PubMedID: 8854833

Title : Resistance to organophosphorous insecticides in Culex pipiens quinquefasciatus (Diptera: Culicidae) from Martinique - Yebakima_1995_J.Med.Entomol_32_77
Author(s) : Yebakima A , Raymond M , Marquine M , Pasteur N
Ref : Journal of Medical Entomology , 32 :77 , 1995
Abstract :
PubMedSearch : Yebakima_1995_J.Med.Entomol_32_77
PubMedID: 7541837