Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....
9gamm-e1msw2   	-------MLSI----------LLTYLLLL---------------------------LLVFLF--------QRKMIYFPDTYSIE--DQQQRADQ----ANLKLWPS------------------------TVDYRG--LIAKTPQSTN--------KGTVIVFHGNAGSATDRTYYLDALEK--LSYRVILAEYPGYAARK----------------GAP---SEQALISDGIQTAKQALND-F----GGPVFLWGESLGGGVASGIVQS-----------GQVPVKGIVLVTPFSSMADVAQHHYWF----L----------LAK---WLIKDK-FDN--------------------------------------IK--NLKDYAGNTAIL-------L--------------------------------------AEQDEIIPNKLSLKLFDSLHHAKKLWSFKGANH-N------------------------T----LP---LADELPYWQEVM-QFVSGQNG-VSP-------------------------------------------------------------------------------------------     =====>
9viru-d2tf43   	----------------------------------------------------------------------------------------------------------------------------MVYEAIDDTLIHYSYNK-----------CNGNYNCVAMIHDIFASKESWFYLQQHFTK--SNITNISIDIPGFGASPTL----------------T--TKYDYSYRSLAVIISLLLTK-LAI---GPCIVIGHGTGCIIAASLSTISA-------N-----IKGIVMLSPNFDTPPSYLKVAPS----------------------CFVSSYVSRICK---------------------QYYQY-------NRLETLHEHQ------II-----VKP-------------FKHHFQNSYRR------------DVVERMIYAVESSYIDIIEMIF-CPLFTIAPSKEKHAIHS----------------------------------------NVLTTLA--DAGSTFKFVDHVGNFMHHEAPELIFTYIYEFVK--------------------QLTKS-DMS---I--------------------------------     =====>
bruma-a8pnw8   	-----------------MST---------------------------------------IRSI-------GNQKLPMKLEGVPS--VLRTLRIR----IDFFDRKS------------------------IDVNAI--VQDCLPDGSC--------IGTVVGCHGTPGSHNDFKYILPYLHS--YGIRFIGINFPGQGYTP----------------HHE---ELNYTNEERMQFVQKIINM-MDV--GDNIVFLGHSRGTENALRLAARNP-------DR----CKGVALINPIGIKVHHSIKPTWL----IIFGLWLWETFKIF---RFILRYLFYR----------------------------I-------FQMLKMKVKN--GDEAAI-------C-----------------------------------LKLTTNIDLTDQMRYINMLNNNK-TKVLIAYSALDH-LIEISISQQ-FASLFDNISH----MNCSSATG----SNMSSVLDYIPKQYAQTDRS-FSVCFENEGHYLQKYQAKFIANCTYSMLI--------------------ARNSL-HQN-------VENGFKSLL--------------------     =====>
caebr-a8wny7   	--------------------------------------------------------------------------------MSEP--IVHRKLVK----FQKLDGKA------------------------AEVQAV--YEDSLSSGSS--------VGTVVAFHGSPGSHKDFKFIRQRLDA--MGVRFIGINYPGFKQTE----------------GYA---GQDHSNEERQSYTNAFLKD-MSL--SGKVIFLAHSRGCENALMTATTFP-------------ATGLVMMNPVGLRLHKSLRPLSR----YQRLESVYNMLPK-----FLGDAMIYK----------------------------M-------YHSFGLKVQD--GEEAIN-------A-----------------------------------LRSVIRCGLDKTLPYIQKLQKQD-TKNFIIFAGRDI-IVEEEIIFE-SLKEYKDLEH----FDYEYDIP----FDD---FSKILKTFD-SGKG-ASVFVKKDKHYQNKARADLVAEVVRKILD--------------------LDGVK-KNK-------L----------------------------     =====>
caebr-a8x5s6   	-------MLATRNILTRNRIIIFRNIASVSDQASN-----------------MDIDV--FQIQ-------IRKKSARSTTYFDL--NEYMKVINVTYKTGEAMDRF------------------------TTVESK--YVDIGDPAGT--------KGTVVTLSGSPGTHNDFKYMKLLFEQ--KKIRMISTNYPGSEFVS----------------GGL---HNSYTNKDRNSYMKSLMEK-LELKNVNKLVIMGHSRGGENALQMTSELS-------DDSNWPLVGAVMINSPGFAPHKGISKR------MGAINFIISLIKRH---NPTINMILHPILHWF-----------------------Y-------NDVIGLRVSH--GKVAAA-------A-----------------------------------ILPMQTFAFDEQKLNIDDLKNKPNVRVFYGYGSKDF-LIDEHQSEE-VAMYFSNKNH----YIIKNKDD----AEK--AKQKIQENIKSGDQF-ITANFTNEGHFLQKTYPEFIVDVVNVFFD--------------------ADTDR-EK-------------------------------------     =====>
caebr-a8xfe6   	------------------------------------------------------------MAT-------AVEKALLKQPYFDL--NTLCKTVFVTYKAGPKLDKI------------------------VTVQSQ--YVDICNKPGV--------RGTVVSLAGSPGSHNDIKYMRDSFEK--HNIRLVCTNWPGSEFVT----------------GGL---RDSYTNDERNSYVKALMEK-LGMKKVEKLIVMGHSRGGESALQMACILS-------EDRSWPLIGAVMINSPGFVPHRGISMR------MGTINTLAYLIKLR---WKAIDSVLFPVLDWF-----------------------Y-------NDFVGLRVAD--GKVSAA-------A-----------------------------------ILPMQTFAFDKQKVSMDEMKKKPWVRMFYAYGSDDF-LVDESDSEE-LAMYFK-GDH----YVIHNRKE----SEE--AIPKIWDSYARGQSY-VTANFTAEGHYLQKTYPEFLIQVLGGMFD--------------------VETKG-PK-------------------------------------     =====>
caebr-a8y100   	--------------------------------------------------------------------------------MDPI--KIEKKLIK----FQATDGRE------------------------VELEAV--YEDTIPSGSS--------LGTVVGFHGSPGSHKDFKYVRSKLDE--MGIRFIGINYPGFGNTL----------------GYE---NQGHTNPERQNYTNALLDA-VKV--EGKIIFIGHSRGCENALQTAVGRP-------------AHGLVLINPTGFRHHKGIRPVYR----LEYLDWLYGILPA-----FMGNAM-MG----------------------------V-------YKAIGFRVKT--GEEAIC-------A-----------------------------------LRSAMSMSFENQIEYIEKLNETE-TKKLIIFGGSDH-LVEEEIVLE-KLEKHDGLEH----FRFEDSIP----EED---KLKIMDSFS--RKG-ASVFVAKDTHFQNKSQAVLVAEACGKMLE--------------------IA-------------------------------------------     =====>
caebr-a8y101   	--------------------------------------------------------------------------------MSEA--NLCKKLVR----FETENGRN------------------------IELEAV--YEDSLSSGSP--------LGTVVGFHGSPGSHNDFKYIRNRLDE--LNIRFIGVNYPGFTFTD----------------GYS---SQQHTNIERQNYSNALLDK-LGI--PGKIAYIGHSRGCENALETAVGRS-------------GHGLVMINPIGLRIHRGINPISR----MEAISWMYEMLPT-----FAGNAMMLG----------------------------L-------YKMVGFKIQT--GEEAIN-------S-----------------------------------MRSMCRVSLGGQLEFIEKTNEMD-IKKLIVFAGKDH-LNFEN-----------------------KKIP----EED---QLKIMDAF--SRKG-ASVYVANDTHFQNKSQAVLVADACRAMFE--------------------NGKTT-KNK-------L----------------------------     =====>
caeel-C31H5.1  	------------------------------------------------------------MAT-------AVELALLKQPYFDL--NALCKTVFVTYKAGPGLKKI------------------------VTVQAQ--YVDICNKPNV--------RGTVVSLPGSPGSHNDIKYMRDSFEK--HNIRLICVNWPGSEFVT----------------GGM---NDTYTNAERNSYAKALMEK-LELKKVEKLILLGHSRGGESALQLACTLS-------DDRSWPLIGAVMLNSPGFVVHRGISIR------MGTINTVSFLVKLR---WKIVDCILFPVLDWCRFTVKLFVFQF--------FYTVY-------NDFVGLRVSD--GKVCAA-------A-----------------------------------MLPMQTFAFEEQRASIDEMKKKPWIRMFYAYGSKDF-LVDESDSEE-LAMHFG-GDH----YIIHSKKE----SEE--TIPKIWNSYERGQSY-VTANFTEEGHYLHKTYPEFLIQIFGGIFD--------------------VKTEK-S--------------------------------------     =====>
caeel-F10D2.10 	-----------------MAALQFSSNALK------------------------------RVVL-------GSQFRSFASKMTEP--NMHRKLVK----FQAENGKQ------------------------VEVQAV--YEDSLSTGSS--------VGTVVAFHGSPGSHNDFKYIRQQFDE--AGIRFIGLNYPGFKQTD----------------GYP---GQGHCNKERQNYTDAFLKS-ADL--SGKVIFLAHSRGCENALMTATTFP-------------AHGLVMMNPLGLRKHKSIRPLSR----LERIEWVYDMLPK-----FLADAMIYR----------------------------M-------YLSFGLKVQD--GEEAIS-------A-----------------------------------LRSVIRCGLETTLPNIHKLREQD-TKTFIIFAGKDL-ICEDEIVFE-ALKEYRDLVH----FDYDSEIP----TDD---YGKILKTFD-SEKG-ASVFVAKDTHFQNKKRADLVAEVVKKIFD--------------------AEGTG-KNK-------L----------------------------     =====>
caeel-F35H12.5 	-------MFSSRHILSNVRP-------------------II-----------KNLDL--T-----------RGFSDRKTKYFDL--NDLIKTVNVTYKTGVNLEET------------------------TTVESK--YVDVTPSSNT--------KGTVVTLSGSPGTHNDFKYMKSFFEQ--KKIRLICTNYPGSEFVT----------------GGL---HNSYTNQDRNSYMKSLMET-LELKNVNRLIIMGHSRGGENALQLTSMLS-------NDENWPLVGAVMINSPGFAPHKGISKR------MGTINFIISLIKRH---NKTINSILHPILHYF-----------------------Y-------NNLIGLRVSH--GKVAAA-------A-----------------------------------ILPMQTFAFDEQKLSIDDLRAKPGIRAFYGYGSKDF-LIDEHQSEE-VAMYFSEEDH----YVISNKQD----AEK--AIKEARKSFTTGKQF-VTANFKEEGHFLQKTYPEFIVEVVDSIFD--------------------ADKEV-DTK-------I----------------------------     =====>
caeel-K08D9.4  	-------MEKVRFFFLNTNLIKFDNISKS---------------------------I--MIMS-------KGAFSTL--PATEP--KLYSKLVQ----FQTKRRRL------------------------VDLNAV--YEDSLSSGSP--------LGTVIGFHGTPGSHRDFKYVRQRLEH--MNIRFIGINYPGFKQTP----------------AYP---GQHFGNWERNSYSEALLNE-LDV--PGKVIIMGHSRGCENALITAANRK-------------PHGLVMANPTGLRINKGSRPKGK----LESLIYLHKKLPK-----KIGDAILYN----------------------------L-------MKLVGFKIHD--GEEAVA-------V-----------------------------------IRAIMNCDLEKQLEYILKLNELP-TKTMITFGGSDH-LIEKEIVFE-ALKKYQGLAH----FNFKANIT----ESE---KQKIMESFK-NQKG-TSVFIAKDNHFQNKKRADLLADAARSMLL--------------------N--------------------------------------------     =====>
caeel-Y73C8B.1 	-----------------------------------------------------------MIVS-------KRAFSIL--PASEP--KLYSKLVQ----FQTKRGRL------------------------VDLNAV--YEDTSASGSP--------LGTVIGFHGTPGSHKDFKYVRQRLEH--MNIRFIGINYPGFKQTP----------------AYP---GQHFGNWERNSYSEALLNE-LDV--QGKVIIMGHSRGCESALITATNRK-------------PHGLVMVNPTGLRIHKGSRPKGK----LESLVYFHKKLPK-----TVGDTIMYN----------------------------L-------MKSVGFKIQD--GEEAVA-------V-----------------------------------IRAIMNCDLEKQLEYILKLNEQP-TKTMITFGGSDH-LIEKEIVFE-ALKKYQGLAH----FNFKANIT----ESE---KQKIMESFK-NQKG-TSVFIAKDNHFQNKKRADLLADAARSMLL--------------------N--------------------------------------------     =====>
caeel-Y73C8B.2 	------------------------------------------------------------------------MTEVPRARISEP--KLLKKLVK----FQAENEQF------------------------VELEAV--YEDSITSGSP--------FGTVVAFHGSPGSHNDFKYIRSKLDD--LNIRFIGVNYPGFSNTP----------------EYE---GQQHANPERQNFSNALLDE-LKI--DGKIIYMGHSRGCENALQTAVGRE-------------AHGLVLINPTGFRHHQGIRPFYR----LEYLDWMYGLLPS-----FLGNSMILG----------------------------I-------YKAIGFKVKS--GEEAMC-------A-----------------------------------MRSVMRMSLEDQIEYIEKLNQKH-TKKLIVFGGNDH-LVEEEIVLE-KLEKHDGLEH----FRFEDGIS----EEE---KSKIMECFTGNQLG-ASVFVAKDTHFQNKSQAELVAESCKKMLD--------------------A--------------------------------------------     =====>
caeel-Y73C8B.3 	--------------------------------------------------------------------------------MTEP--NLCRKLVK----FETESGKK------------------------VELDAV--YEDSLTSGSP--------FGTVVAFHGSPGSHNDFKYIRSKLDD--LKIRFIGVNYPGFTFTN----------------EYP---DQKHINIERQNYSNALLDE-LGI--DGKMAYIGHSRGCENALQTAVARD-------------AHGIVLINPTGLRIHKGINPISR----MTTVDSIYKMLPL-----FLGNAMMLG----------------------------V-------YKAFGFKITT--GEEAVN-------S-----------------------------------MRSMINVSLGGQLEFIEKTNDMN-VKKLIVFAGKDH-LVEEEIVFE-TLEKHEGLQH----FNIDKEIS----EAE---RLKILDSFTGTQRG-ASVFVAQDNHFQNKSRAGLVAEACKAMFE--------------------NEKTS-RNK-------L----------------------------     =====>
caere-e3lkx0   	-----------------------------------------------------------------------------MTTMTEA--NLCRKFVN----FETENGRK------------------------IELEAV--YEDSLTSGSP--------LGTVVGFHGSPGSHNDFKYVRNRLDE--LNIRFIGVNYPGFTFTD----------------GYS---SQEHTNIERQNFSNSLLDE-LAI--DGKIAYIGHSRGCENALQTVVTRS-------------GYGLVMINPIGLRIHKGINPISR----MEAIDTLYSWLPS-----FAGNAMMLG----------------------------L-------YKLVGLKIQN--GEEAIN-------S-----------------------------------MRSMMKVSLGGQLEYIEKMNKMD-VKKLIVFAGKDH-LVEEEIIFE-SLEKHEGLQH----FNIEDKIS----DEE---KQKIMDSFGGSQRG-ASVFVAKDNHFQNKSQAVLVADACKAMFE--------------------VNETV-KNK-------L----------------------------     =====>
caere-e3lkx1   	----------------------------------------------------------------------MEETPAPRARISEP--KLQKKVVK----FQTEIEKD------------------------VELEAV--YEDSLSSGSS--------LGTVVGFHGSPGSHNDFKYVRNKLDE--MGIRFIGINYPGFGNTP----------------GYE---GQEHGNPERQNFTNALLDE-LKI--EGKIIFIGHSRGCENALQTAVGMP-------------SHGLVLINPTGFRHHKGIRPVYR----LEYLNSLYGILPS-----FMGNAMMLG----------------------------I-------YKAIGFKVQS--GEEAIN-------A-----------------------------------MRSAMRMSLEDQIEYIEKLNQKN-TKKLIIFGGNDH-LVEEEIVLE-KLEKHDGLEH----FRFGDNIN----EDE---KLKIMETFTGNRLG-ASVFVAKDTHFQNKSQADLVAEACKKMLE--------------------A--------------------------------------------     =====>
caere-e3lkx2   	-----------------------------------------------------------MIAS-------KRLISTVNTTVRAS--KLHEKLIQ----FESEKGKI------------------------VDLKAV--YEDSLPSGST--------LGTVVGLHGSPGSHKDFKYIRHRLDD--MGIRFIGINYPGFKHTE----------------AYP---SQRFGNVERQRYSDSLLNE-LDI--RGKVIIMGHSRGCENALITATHRN-------------PHGLIMINPTGLRIHKGSRPKGK----LESLNYMHKQLPK-----KIGDKVMYQ----CEFLKSFSS-IL--------NLISV-------LKTVGFKIQD--GEEAVA-------V-----------------------------------IRTIQKCDLEKQLDYILKLNEMP-TKTMITFGGRDH-LIEKEIIFE-ALQKYQGLKH----FDFKSDIS----TDE---KQEILDIFK-SHKG-TSVFVARDNHFQNKKRADLLADGVKSMLI--------------------H--------------------------------------------     =====>
caere-e3lvt5   	------------------------------------------------------------MAT-------AVEIALAKQPYFDL--NSLCKTVFVTYKAGPKLDKL------------------------VTVQSQ--YVDICNKPGV--------RGTVVSLAGSPGSHNDIKYMRDSFEK--HNIRLVCTNWPGSEFVTGETHDDTCKCIVQLDSGGL---RDSYTNEERNSYVKALMEK-LGMKNVEKLIVMGHSRGGESALQMACILS-------EDRSWPLIGAVMINSPGFVMHRGISVR------MGTINTLAYLIKLR---WKMIDCVLFPVLDWF-----------------------Y-------NDFIGLRVAD--GKVSAA-------A-----------------------------------ILPMQTFAFEKQKASMDEMKKKPWVRMFYAYGSKDF-LVAESDSEE-LAMYFK-GDH----YVIKDKKE----SEE--AIPKIWNSYANGQPY-VTANFTEEGHYLQKTYPEFLIQVLGGMFD--------------------VETKS-SK-------------------------------------     =====>
caere-e3m012   	--------------------MIFGRTALL---------------------------K--TTGQ-------IRNFAVASTEMSEP--KVHKRPVK----FPKMDGKP------------------------VEIQAV--YEDSLSSGSS--------VGTVVAFHGSPGSHKDFKFIRQKLDD--MGVRFIGINYPGFKQTD----------------GYS---GQQHCNEERQNYTNAFLKD-LSL--TEKVIFLAHSRGCENALMTATTFP-------------ADGLVMMNPVGLRIHKSIRPLSR----LQRIEYVYDLLPK-----FLADAMIYR----------------------------M-------YHSFGLKVHD--GEEAIN-------A-----------------------------------LRSVIRCGLETTLPFIQKLQKQD-TKTFMIFAGRDI-IVEEEIIFE-SLKEYKNLEH----FNYDTDIP----SDD---FSKILKTFD-SRKG-ASVFVKKDTHYQNKLRADLVVEVVKKIFS--------------------LKNKL----------------------------------------     =====>
caere-e3ma45   	MFFFSFQMLSTRHIVSNCQISRLGYLVKVSQHLKQVYTVHF-----------QNHEL--IRRY-------CVANSAKPTKYFDL--NDLIKTVNITYKTGKEMDQI------------------------TTVESK--YVDVNNVPDT--------KGTVVTLSGSPGTHNDFKYMKSLFEE--KNIRMICTNYPGSEFVT----------------GGF---HNSYTNEDRNSYMKSLMET-LHLQKVNRLIIMGHSRGGENALQLTSQLS-------DSSSWPLVGAVMINSPGFAPHKGISKR------MGTINFIISLIKRH---NNTINAILHPILHWF-----------------------Y-------NNVIGLRVSH--GKVAAA-------A-----------------------------------ILPMQTFAFDQQKQSIDDLRQKPRIQVFYGYGSKDF-LIDEHQSNE-VAMYFAKDNH----FVITDKTA----AEK--ASQEVRKSFNAGRKF-ATANFTKEGHFLQKTYPQFIVEVVDSMFE--------------------ADTSK-K--------------------------------------     =====>
decar-q47c71   	----------------------------------------------------------------------------------------------------MKHVTV------------------------KGLKLE--YRDYPATTEG--------RPTLLLLHEGLGSVTMWRHFPEKLAA-ATGCRLIVWSRAGYGGSE----------------PYPEPRTVRYMHREGEEMLPALLEA-LK---IERPILIGHSDGGSIALIFAGAFP-------EE----PLGVAVMAPHEFVEAETLAGIRAARQLWDDTDWPQKLARYH---RDAPRVFSDWNDCWL-----------------------S-------PPFCDWNIEEY--------------------------------------------------------------------LPKIR-CPVLAIQGEDDE-YATM------------------------RQIE------------VI----AEQVPGTSLLKLPKCGHSPQRDQEALVLDALAAFVS--------------------RASGS-CR-------------------------------------     =====>
ehv86-q4a332   	----------------------------------------------------------------------------------------------------------------------------MVYEAIDDTLIHYSYNK-----------CNGNYNCIVMIHDIFASKESWFYLQQHFTK--SNITNISIDIPGFGASPTL----------------T--TKYDYSYRSLAVIISLLLTK-LAI---GPCVVIGHGTGCIIAASLSTISA-------N-----IKGIVMISPNFDTPPSYLKVAPS----------------------CFVSSYVSRICK---------------------QYYQY-------NRLETLHEHQ------II-----VKP-------------FKHHFQNSYRR------------DVVERMIYAVESSYIDIIEMIF-CPLFTIAPSKEKHAIHS----------------------------------------NVLTTLA--DAGSTFKFVDHVGNFMHHEAPELIFTYIYEFVK--------------------QLSKS-DMS---I--------------------------------     =====>
enthi-b1n449   	--------------------MIWEIIAGATALI-------------------MVLSG-----IHLFTH--QYEIVFYPTRHTLPSVEEITQTFQLP--FELKEVSI-------------------FT---NDNNTVYLYACLKEEPSK--------HITLLLFQSNAGSVLDRMEMAKKYYE-LCNVNFVIAVYRGFDKST----------------GIPEEVT---MNNDVEKYFDS-LES-LGV-DMNNIVVIGRSIGASMALKLYNKKN-------------CKGLIIENGFTTLLDVG--KIL-----MPAISFFPWLIKDK---WDNLNEIKHV--------------------------------------------------------------------------------------------------------------------QKG--KRILFCSSGQDE-MVPPSMMQH-LYDVAH-----------------------------------ETGKKVRMEKFAKGFHMNLPSYPEYFKKLN-KFFE--------------------ELTKE-TME----EGIIENQEVQ----------------------     =====>
ixosc-b7pv10   	--------------------------------------------------------------------------------------------MQCSLRVVLGAMGTIQCGAVLP-----------VYLRGIEVPVR--YLHT---GLD-R-AWDAGRPTVLLLHGAPGSYRDFTDLVPFLDR-V-GATVVSPTWPDLKLSY----------------RVG---TFWHSAEEKTHLLADFLRA-INISKID--LVVAHSSAIYPSLNMMTRPG----------MPAVGGLALLAPAGHQLVRAIRPLPL----MRAFAVHYTNPRYQ---GFMRRLGIA-----------------------------I-------MKCTRNPIKPN-MEDAIM-------S-----------------------------------LQTMIFSDYDQAGHKIKQVAESG-TPLLIAFSENDR-AINPEVIFN-MVDLIGTRNEDLWLYDADGKLA-----------RE-------ARVD-AMVCGHSGDIHGL---------------------------------------------------------------------------------     =====>
ixosc-b7q231   	-------METT----------------------TAIYP--------------------------------HRRSQALPFPKTDR--ET--AAVQDEALYKERTVTVHTCAELFPKWKRSRPGWKHVRADGVDVPLP--YIHT---GLD-R-GCAEG-PTVLAVHGAPGTYREFDALTPVLDV-HGGASVVVPTLPDLEFSM----------------KTQ---SFWHSVEEKTDLLKKFLEA-INVREID--MVIAHSSSMYPILWLALKEP----------DIRIKSAVFIAPPGCRRISQLSPFWM----MKAFDEWFRVPGLQ---NLMCDMAVH-----------------------------I-------VRMLGKPNNNQ-IRGTIL-------S-----------------------------------MITIMHAGYDQSEPLLRELQQRQ-VPMLMLYGEKDR-LIDREVSAE-MAAVLGVQPSQMQVYMGKDNAH-----------ARLENPGEPVGNN-EVVCFKEGTHFAFKKYPDIFNDVILKFWR--------------------KHVKA-GI-------------------------------------     =====>
loalo-e1fx99   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDV--GDNIVFLGHSRGSENALRLAARNP-------DR----CKGVALINPIGVKAHHSIKFTWL----INFGLWSWETFKIF---RFILRYLLYK----------------------------I-------FQMLKMKVKS--GDEAAI-------C-----------------------------------LKLTANIDLIGQMNYINMLNNNK-TKVLIAYSTVDH-LIEISVSQH-FASLFDNITH----MNYPSTDG----N--TSILDYIPEQYAESDRS-FSVCFENGGHYLQKYQAKFIANCTYSMLI--------------------AKNSM-YQN-------DENVLKSRL--------------------     =====>
loalo-e1gjb1   	-----------------MNN---------------------------------------MKSL-------GGQKSSIMLEQVPS--VLRKLRVR----IDFIDRQS------------------------IDVDAV--VQDSLPGGPC--------IGTVIGCHGAPGSHNDFKYIVPYLHK--CGIRFIGINFPGQGYTP----------------HYE---ELNYTNEERMQFVQKIINS-MDV--GDNIVFLGHSRGSENALRLAARNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
mycfe-c4xfu4   	-----------------------------------------------------------------------------------------MSKI-----------------------------KVIFNIIINTMKLN--YIEYNGDKVPLYIEDNKKNTTFLFLHGL---NSNWKYMRPLLDY-THNYNVVAINFPGSKFFKNV--------------EPEEIKLEW-----WIEVANEVLNR-I---KTKKVVIVAHSMAGGVATVLAKDPK-------------VVRLIMMST--------INPYMKESTSY-----------------SVLQSVIKPQNKWSSFIGKVISKIASKFKKTEKLIESFTRQGAWFNLLEKYVLNP----------------------------------------------------------EY---MEQLDLQYKANCHKMLFLVGEKDK-IIGTKYFED-YAISLE-----------------------------------------VPILIMGTGHSPIKDEPKRIARFFNALIESKKRHFWQKFMNIKMNQFLEFDEEK-TKEEDILLELEQNVD------------------------     =====>
mycfj-e1prc7   	------------------------------------------------------------------------------------------------------------------------------------MKLN--YIEYNGDKVPLYIEDNKKNTTFLFLHGL---NSNWKYMRPLLDY-THNYNVVAINFPGSKFFKNV--------------EPEEIKLEW-----WIEVAKEVLNR-I---KTKKVVIVAHSMAGGVATVLAKDPK-------------VVRLIMMST--------INPYMKESTSY-----------------SVLQSVIKPQNKWSSFIGKVISKIASKFKKTEKLIESFTRQGAWFNLLEKYVLNP----------------------------------------------------------EY---MEQLDLQYKANCHKMLFLVGEKDK-IIGTKYFED-YAISLE-----------------------------------------VPILIMGTGHSPIKDEPKRIARFFNALIESKKRHFWQKFMNIKMNQFLEFDEEK-TKEEDILLELEQNVD------------------------     =====>
mycfm-e8uhb0   	------------------------------------------------------------------------------------------------------------------------------------MKLN--YIEYNGDKVPLYIEDNKKNTTFLFLHGL---NSNWKYMRPLLDY-THNYNVVAINFPGSKFFKNV--------------EPEEIKLEW-----WIEVAKEVLNR-I---KTKKVVIVAHSMAGGVATVLAKDPK-------------VVRLIMMST--------INPYMKESTSY-----------------SVLQSVIKPQNKWSSFIGKVISKIASKFKKTEKLIESFTRQGAWFNLLEKYVLNP----------------------------------------------------------EY---MEQLDLQYKANCHKMLFLVGEKDK-IIGTKYFED-YAISLE-----------------------------------------VPILIMGTGHSPIKDEPKRIARFFNALIESKKRHFWQKFMNIKMNQFLEFDEEK-TKEEDILLELEQNVD------------------------     =====>
nech7-c7z7w8   	----------------------------------------------------------------------------------------------------MGASPR---------------TLLIFRLPSTKRLIS--WAEFGSPN----------GRPIIYLHGTPSSRLECAGFHQELHD--RNIRLIAPDRPGFGRSEVQ----------------PGRTI-----GGYASDVRALAKQ-LNL---SGYAVMGQSGGGPYALACARYIR-------P-----EDGLRAVAV-----LGGLSPFESE---FE---------GAH---WAT--SFSLKMAKWAPGLLGFFL-----------RLPIPSRKGNFTGPLEEWTVDPSMLAEAEKTQQAFVNTMKGREKEVMSEPGVVHHLTTTFVEATIQGVDAHLYESKLFAQGWDFKLQDITFASEGK-RPLIMWYGAKDV-NTTVHMGKW-IAERVAGS---------------------------------------QLREVDGETHNT---LVVKFVDYCDELLK--------------------VSNG-----------------------------------------     =====>
phyit-d0n4x0   	-------MKAV------LRA--SRPVRSVAKQRVS-------GP--FL-SVPPSLGAL-SFS--------TAKLRPSLPPLPEP------SFIGVDN----------------------------------KCKIE--YIDVKPEDLS------AATPTLVLIHGAPGTYRDFRHLIPLLKE--RGVRVVGVNLPGFAGSTILDTSNYYDHISAFPS-----------VQLTYKAMQGVL------KDSDNVFVLGHSFGGHAAVHFTGINA-------DEQGINVKGLVLLAGAGHRPHQALSPRL--------NDFLWKMLRSG---VPVVESTSKWLVR-----------------------QLY-------IRSFKFPDSKL-PDYFTA-------G-----------------------------------IVRCATADFPLFAKHL--EKNRS-LPSFLAWAKDDA-LIEEEIFMD-VSAV--------------------------------------CHPG-PRLAFEKGGHNVQKTKATFLAEELTDWMN--------------------NVVRG-REQ---SEVYSTNVEVHP---------------------     =====>
phyit-d0n4x1   	-------MLRV------LHARLLSCVRSYSR---------------WN-----VLPQV-EMA--------SREARAPPPPLPSP------KYLEIRR----------------------------------RCTIE--YVDIPPLNEAVG-SHSEDPVTLVLVHGAPGSYSDFRHLIPKLNR--PYMRILGLNLPGYAGSRVS-EEHYLDSISALPT-----------ADLALEAVQKLCD-------SGNVFLVGHSFGAHTVINMAALET--------HEKFRVRGMALLAPAGCRPHKVLRPRE--------SAMVVSLLRRD---NAVLSTLTSHLIK-----------------------AIY-------TRLLKFPSDHP-PGHYIA-------G-----------------------------------LVRAGTTDFNVIREQVDMLRKRK-MPSLVAWSQNDE-FMEEEIPVE-LARL--------------------------------------CHPG-PRLKFARGGHNVQKTRADQIADALSRWIE--------------------EVLDK-EGR---VN-------------------------------     =====>
phyit-d0n4x3   	-------MPAT------GYLGILPCCRS-------------------------------PRV--------VHEPQSPPPPLPDP------KYLQIDN----------------------------------ICKIE--YVDVEPQQSV--------SATVVCVHGAPGSFRDYRYLIPMLAEQQRGIRLIGVNLPGYMGSEVE-KAHYLKTVSALRA-----------AEVVLQAIRQLCGT-IE-MDGGDIVLVGHSFGAHTVINMAAMNETLRVAGDNVNTIRLRGIAVLAPAGCVPQRMVKEIP--------IKMLVTLLRSR---STVVVRLATRFVK-----------------------YLY-------TELLGFPRRTP-ATSCVS-------A-----------------------------------VIRAGTTKFPLIRTQVNFLKEMK-MPVFVAWALDDV-LVEPEIPEE-LGKL--------------------------------------SHPG-PRLEFAGGGHNIQKTRVEQVTAAMSSWIQ--------------------SILSE-CNS---LETGMTQ--HLP---------------------     =====>
tetth-q22wx3   	-------METNNEKYSYT------SLSR-----VE----------------N--FPIFEKI----------YSVCKENQNKFSIELVKKQKKDLVQYK----SHLI--------KRAQFDDGW----------FCF--YTDNLGDHSH----FECKE-IVLTVHGFPGNWRDWQPIETYIGN--NFCRWINLFVPGFDGETETNRG-----------------SYKGYITQLADLVVRLIKEHLKI--SQKMILFGYSGGNIVVRLLQQKYP-------EI----CKAHINLV-GPTIIWNPAHLYMYH--VFNTFDREFKLREHP---EQLEDPKVREKL--------------------------Y-------EKFKLFQMGDY----------------------------FVYEKVPIWCD-THETLMIWFKKFLSFPEGWSKFYE-IGHNQQ--DILRFYATGDIDP-LVDSQLLFYEFYHNTY-LRQ---VFKITDEQTKQKILSNKYLSQLKNFNFENVQEN-FLFMFPRTGHTIHIKRAYELAFPLKCFISLI---------NILPDNYYEINKQQTPNNPYIGNIFIPK-----L--------------------     =====>
tetth-q24fe1   	-------MSQDNKYEQYL------YDQR-----DD----------------ETVDKQATIV----------KQYCDRNRKQILPAINKQLKYEQENYKGYKSNSLI--------LRMDFSDGS----------FVQ--YADNVSSNSS----FKFSNRCILAIPGVPGSIKDFAPIEKRLEP--NFCRFIHLFLPGFDNIDE-RRG-----------------QYVGTLQDGVKMINEFLNK-LGI--QKV-VIMMHSLGGFFGKYFACCNP-------ER----VDGLIQIASIPLTEWHGWTFMRST------YENAYYLSENE-SFSYYNSDEARKKLQQGSAELKASL-------------AQL-------PKNVQRQFAPA----------------------------LHFSTSDLFC---------LRKITRSLPGGIGEILHNFRKLDS--RIPRLIAYSPKDE-LATKNLYEEEIYDLLF-INN---KVNY---------TIKQQPFKDVQLDLSNFQSN-FVFRVDDGSHYLHFEKANELSVLIRHFIETL---------DYIEVS---------PPQKQRL--------------------------------     =====>
tetth-q24fe2   	-------MKQSQFQYNYT------NDPR-----SQ----------------DEQLNHSKII----------EYYSKRNFKAFLPYVQQQLQNQCID-KSNNIKLNV--------NTMKFEDDR----------YVN--YRDNIDYRDQ----FELKNKTIIFITGVPGGINYYKKIQNSIGQ--QFCRMIDIYIPGFDKKDE-RRG-----------------QYQGGIDQIAKLIDDFMIK-IGI--QSA-VFLAHSYGGIVVKNFIYFKP-------HK----VEGFIQICTVPMTLWEGQKKLEQL------EHQKYNLDFNKISYETLSDENFRQQLKYKIIQTKESL-------------QML-------SEQEKFQLGPI----------------------------VAFSFQDIIT---------MLKIRLSVYGKYNEIFHRFRQLNQ--NIPRMIAYSKNDV-LISANTIEEEIYQYIL-SEN---ALKR---------RITKLESPEPHLDLNNFSSN-YIFRFDDTTHFLQNEKSEEIGIIAKNFIKQI---------DSTQII---------NNKPNL---------------------------------     =====>
triad-b3rks8   	-------MHSG------NLSRFLPRLSK-SSKISDIRRYLP-------AVLQFNAKHLVGLAA------TKSQNFDLPTP-FDP--EV--KFVDVET-GNLNVSSV------------------------DHIRAG--YTDENPNGSP----------TVITVHGCPGSHYDFRYLATPLRD--AGVRIIRINLPGFGPTP----------------KPY---DFTYTPVNKANFVGNLLNN-IGINRVG--MAVGHSMGCACVTSLVSTHP-------NL----VASYALLASCGTRPHFGLRPYMS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DKMPHVTYDLT-TGIS-RQLVFHNSGHYPQKFHANHIGKAMLDILN--------------------KIDGT-KQR-------DQ---------------------------     =====>
triad-b3rks9   	-MPYSLTMYSR------NLSRFLLRLSK-SSKISDIRRYLT-------AILQSNVEHLVGSAATHNRSATKSPIFDLPAP-FDP--EV--KFVNVET-DNLNVSSV------------------------DHIRAG--YTDENPNGSP----------TVIAVHGCPGSHFDFRYLATPLRD--ANVRIIRINLPGFGPTP----------------KPY---DFIYNATNKANFVGNLLNK-IGINKVG--MAIGHSLGCTCVTSLVSTHP-------NL----VASYALLASCGTRPNIGMRPYMW----TRATAKVLDVPLLG---S-LSSVIVNR----------------------------R-------YAKYGFNVAKTVKDEIDN-------S-----------------------------------HRLCANVDFNMNTKCLELMGDKK-IPVLLGFSIDDK-LIEHEIFNE-ISLCLG-MRT----LDEMDGLE----EAQTDKMPHIRYDLT-TGMS-RQLVFQKGGHYLQKFHANYIGKAMLDILN--------------------KLEAV-KEW-------RTNLEHFSWSIGFRLADRFAITRQLTNAR     =====>
triad-b3rkt0   	----------M------HIARLWKRLRV-PASVRDGYSHLQHGLIRKASPIHQCVRHI-SIDACRWNPEDRRGQIDLPTP-IDP--EV--QYVNVQT-KNLGVTSV------------------------DYIKAS--YTDENPTGSA----------IAIAVHGSPGSHYDFRYMAPLLSE--AGVRVIRINLPGFGPTI----------------KPP---DFIYSPVNKANFMAELLES-IGIKKVD--IAIGHSMGCGAITSFPSTHP-------GF----VSSYALLASCGTRPHRSLRPFPI----IKLFANMVNLPVID---K-PSGALLRL----------------------------V-----------------YIKNEIEN-------S-----------------------------------QRLCGAMDFDFNAKNLKLLGDQK-TPVILGFGLNDH-MVEHAIFDE-MSSVLG-LRT----LSEMLALT----NDQGNENPHLAYDVA-TGKS-RQLVFRSSGHYIQKFHARHIAKAILHLLH--------------------DL-------------------------------------------     =====>
triad-b3scg3   	--------------------------------------------------------------MSSNTHQQENDKYDLPTP-SDP--EV--KYTQVST-QNMGITSV------------------------RHFKAS--YTDENPTGSR----------IIIAMHGCPGNHYDFRYLAPPLVQ--KGFRVIRINLPGFGETE----------------KPD---DLQYNPMNLVHFVVNFLSS-LNIDKVD--MAIAHSFSCTVISNLLVTHP-------NL----VLSLGLISGPGLRPHHSISPFSV----VKLLSYLLHFCWLT---KVIIGMILPY----------------------------F-------YRMLGFKVSRFVKGEIEH-------T-----------------------------------QDIVASLDFALHTKNLQCIRDRN-APVILAYGKNDA-LIENAIFSG-IGQTLG-LKT----MKELAEIS----DGQVVENDAVLYELR-TRQS-RQIVFRNGGHYVQKFHAKYIAEMISQVLN--------------------SSNVT-ASL------------------------------------     =====>
triad-b3scg4   	--------------------------------------------------------------MASNKDQHNNNEFELPTP-SDP--EV--KYTQVST-NNMGITSI------------------------NNFQAG--YTDENPTGFR----------IVLAVHGTPGSHHDFRYLAPPLVQ--AGLRVIRVNLPGFGATK----------------KPD---ELVYNFNTMAHWLANFLSS-INIHTVD--MAVGHSFGCAIIATLSVTHP-------EL----ISAFTLLSTFGLRPHRIIRPFAA----IKLSAYLLDLSWVT---NFIATKILTC----------------------------A-------YRMAGFKMSKFVENEMVH-------S-----------------------------------HQLTTNIDFDQHANNLKSIGKRK-VPVILAYGKDDP-LIENEIFSE-VGQILG-LKS----MTELSDLN----GEQG-EIHIPMYNIQ----------------------------------------------------------------------------------------------------     =====>
triad-b3scg6   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLEFSSIT---SAAISSILRY----------------------------A-------FQLSGFNVNKLSKDEMPN-------T-----------------------------------VRMCGIADFQLHHQNLRHISRSK-IPVLLVHGIDDH-LIENKILNE-NCQALG-LKT----LKEMATES---IEPDSQENNSVLYDIK-TNPF-RQIVFKTGGHYIHKIHARYIGEAILRMLE--------------------RNNKE----------------------------------------     =====>
triad-b3scg7   	--------------------MAWLPIARVISRRSTIYYCHNAATMPFAKSLHP---HITIIKSS-L-HQASKFNQELLTP-SDP--EL--LFTNVPG-KYLGLTST------------------------NHFNVS--YTDENSTSPL----------VTLVVHGCPGSHLDFRYISSVLVP--AGVRVIRLNMPGFGSSE----------------KPP---EFIYSAHNLAKFVAAFLDN-IGVTKIN--MAVGISFGCSIVTSLSTVQP-------NL----VLSYGLLSSVGGRPHAGLRPYFS----KDG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....