(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Eukaryota: NE > Opisthokonta: NE > Metazoa: NE > Eumetazoa: NE > Bilateria: NE > Protostomia: NE > Ecdysozoa: NE > Panarthropoda: NE > Arthropoda: NE > Mandibulata: NE > Pancrustacea: NE > Hexapoda: NE > Insecta: NE > Dicondylia: NE > Pterygota: NE > Neoptera: NE > Paraneoptera: NE > Hemiptera: NE > Sternorrhyncha: NE > Aleyrodoidea: NE > Aleyrodidae: NE > Aleyrodinae: NE > Trialeurodes: NE > Trialeurodes vaporariorum: NE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA GIPFAKPPVGMLRFKRPVEIDPWRGVLNATQLPNSCYQERLEYFPGFQGE EMWNPNTNISEDCLYLNVWVPQKLRLRHRRQTNQKVPVLIWIYGGGYMTG TSTLELYDADIVAGMCNVIVASMQYRVGAFGFLYLKPLLPEGMDEAPGNM GLWDQAMAIKWIKDNIAAFGGDPDMLTLFGESAGGGSVSIHLISPATKGL ARRGILQSGTMNAPWSFMEADKAIQIGKILVDDSNCNSSQIEENPSKVFA CMRAVDAKIVSSQQWSSYFGILGFPSAPTIDGVFLPKHPLELMKDQNFED IEILIGSNRDEGTYFLLYDFLEFFEKDGPSLLQRDKFMDIIHTIFKTFSP LEKEAIIFQYTDWENPADGYTNQKMIAEVVGDYFFICPSNYFAQVMADNG DKIYYYYFTQRTSTNLWGEWMGVMHGDEVEYVFGHPLNMSLQYNAENVIS AIESWKLSPILRLQGKPSGVVVEWPQYTRSYPQYFIFHATTSGLGNGPRL TACQFWTDYL
Reference
Title: Characterization of acetylcholinesterases, and their genes, from the hemipteran species Myzus persicae (Sulzer), Aphis gossypii (Glover), Bemisia tabaci (Gennadius) and Trialeurodes vaporariorum (Westwood) Javed N, Viner R, Williamson MS, Field LM, Devonshire AL, Moores GD Ref: Insect Molecular Biology, 12:613, 2003 : PubMed
Gene sequences encoding putative acetylcholinesterases have been reported for four hemipteran insect species. Although acetylcholinesterase insensitivity occurs in insecticide-resistant populations of each of these species, no mutations were detected in the gene sequences from the resistant insects. This, coupled with a series of experiments using novel reversible inhibitors to compare the biochemical characteristics of acetylcholinesterase from a range of insect species, showed that the cloned cDNA fragments are unlikely to encode the hemipteran synaptic acetylcholinesterases, and there is likely to be a second ace locus.