Gene_Locus Report

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Gene_locus Report for: strav-SAV1549

Streptomyces avermitilis probable esterase/lipase (putative esterase/lipase)

Comment
Caution weak similarity not homologous in the Serine region


Relationship
Family|6_AlphaBeta_hydrolase
Block| X
Position in NCBI Life Tree|Streptomyces avermitilis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Streptomycetales: N E > Streptomycetaceae: N E > Streptomyces: N E > Streptomyces avermitilis: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AB070942, AP005027
1 UniProt : Q93HH1
1 Interpro : Q93HH1
1 Pfam : Q93HH1
1 PIRSF : Q93HH1
1 SUPERFAM : Q93HH1
Sequence
Graphical view for this peptide sequence: strav-SAV1549
Colored MSA for 6_AlphaBeta_hydrolase (raw)
MIFRTTDSTTRPALRRVRTTTTLRPLHHRLDPARVEEIPFRAGDGVRLGL
TRVDSGEPDRPAVLLLHGHTASADMFLLPETRNLVDALLDDGYEPWLLDW
RGSCRLPYNETGQKYTYDDVALYDIPAAVSHIRGRIGDRPLFVVAHCIGS
LTLSLSMTAGLVPGLAGVVSQGVFLTPKLAGRTSLRMSVAGELLKTRIDH
IPVDFRKVGLWSKYTPLFALASRKASCPDPTCQILHNSAWGTGASLFVHE
HLSEATHDRLAELLGPAPLWILPHLRRIELARSVVRWHDTDHRYRELPQN
ALDAAGRIDTPVLLIAGSENGLWLDSQKLCHDVLARRQPYLDVSYTEIPG
YGHLDTFLGRGAALDVFGHILDFLGERR
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MIFRTTDSTTRPALRRVRTTTTLRPLHHRLDPARVEEIPFRAGDGVRLGL
TRVDSGEPDRPAVLLLHGHTASADMFLLPETRNLVDALLDDGYEPWLLDW
RGSCRLPYNETGQKYTYDDVALYDIPAAVSHIRGRIGDRPLFVVAHCIGS
LTLSLSMTAGLVPGLAGVVSQGVFLTPKLAGRTSLRMSVAGELLKTRIDH
IPVDFRKVGLWSKYTPLFALASRKASCPDPTCQILHNSAWGTGASLFVHE
HLSEATHDRLAELLGPAPLWILPHLRRIELARSVVRWHDTDHRYRELPQN
ALDAAGRIDTPVLLIAGSENGLWLDSQKLCHDVLARRQPYLDVSYTEIPG
YGHLDTFLGRGAALDVFGHILDFLGERR


References
    Title: Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
    Ikeda H, Ishikawa J, Hanamoto A, Shinose M, Kikuchi H, Shiba T, Sakaki Y, Hattori M, Omura S
    Ref: Nat Biotechnol, 21:526, 2003 : PubMed

            

    Title: Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites
    Omura S, Ikeda H, Ishikawa J, Hanamoto A, Takahashi C, Shinose M, Takahashi Y, Horikawa H, Nakazawa H and Hattori M <4 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 98:12215, 2001 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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