Gene_locus Report for: parte-a0cb90 Paramecium tetraurelia Chromosome undetermined scaffold_163, whole genome shotgun sequence
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Alveolata: N E > Ciliophora: N E > Intramacronucleata: N E > Oligohymenophorea: N E > Peniculida: N E > Parameciidae: N E > Paramecium: N E > Paramecium tetraurelia: N E 6_AlphaBeta_hydrolase :
parte-a0bds8 Paramecium tetraurelia Chromosome undetermined scaffold_101, whole genome shotgun sequence ,
parte-a0byt1 Paramecium tetraurelia Chromosome undetermined scaffold_138, whole genome shotgun sequence ,
parte-a0cj40 Paramecium tetraurelia chromosome undetermined scaffold_191, whole genome shotgun sequence ,
parte-a0ecy9 Paramecium tetraurelia Chromosome undetermined scaffold_9, whole genome shotgun sequence ,
parte-q6bfm1 Paramecium tetraurelia epoxide hydrolase, putative .
ABHD13-BEM46 :
parte-a0bnp2 Paramecium tetraurelia chromosome undetermined scaffold_119, whole genome shotgun sequence .
ABHD17-depalmitoylase :
parte-a0dwm9 Paramecium tetraurelia chromosome undetermined scaffold_67, whole genome shotgun sequence .
abh_upf0017 :
parte-a0bga5 Paramecium tetraurelia Chromosome undetermined scaffold_105, whole genome shotgun sequence ,
parte-a0c9f4 Paramecium tetraurelia Chromosome undetermined scaffold_16, whole genome shotgun sequence ,
parte-a0cu52 Paramecium tetraurelia Chromosome undetermined scaffold_28, whole genome shotgun sequence ,
parte-a0d1l8 Paramecium tetraurelia Chromosome undetermined scaffold_34, whole genome shotgun sequence ,
parte-a0dem3 Paramecium tetraurelia Chromosome undetermined scaffold_48, whole genome shotgun sequence ,
parte-a0dvl0 Paramecium tetraurelia Chromosome undetermined scaffold_66, whole genome shotgun sequence ,
parte-a0e0g8 Paramecium tetraurelia Chromosome undetermined scaffold_71, whole genome shotgun sequence .
Acidic_Lipase :
parte-a0cq13 Paramecium tetraurelia Chromosome undetermined scaffold_239, whole genome shotgun sequence ,
parte-a0dld4 Paramecium tetraurelia Chromosome undetermined scaffold_55, whole genome shotgun sequence ,
parte-a0dnw2 Paramecium tetraurelia Chromosome undetermined scaffold_58, whole genome shotgun sequence ,
parte-a0dy72 Paramecium tetraurelia Chromosome undetermined scaffold_7, whole genome shotgun sequence ,
parte-a0e8v9 Paramecium tetraurelia Chromosome undetermined scaffold_83, whole genome shotgun sequence .
AlphaBeta_hydrolase :
parte-a0dk36 Paramecium tetraurelia chromosome undetermined scaffold_54, whole genome shotgun sequence ,
parte-a0e9r1 Paramecium tetraurelia chromosome undetermined scaffold_85, whole genome shotgun sequence .
Carboxypeptidase_S10 :
parte-a0cck1 Paramecium tetraurelia Chromosome undetermined scaffold_168, whole genome shotgun sequence ,
parte-a0duj9 Paramecium tetraurelia Chromosome undetermined scaffold_64, whole genome shotgun sequence ,
parte-a0e581 Paramecium tetraurelia Chromosome undetermined scaffold_79, whole genome shotgun sequence ,
parte-a0ecz4 Paramecium tetraurelia Chromosome undetermined scaffold_9, whole genome shotgun sequence ,
parte-q6bfb1 Paramecium tetraurelia serine carboxypeptidase, putative ,
parte-q6bgk8 Paramecium tetraurelia serine carboxypeptidase II, putative .
Duf_726 :
parte-a0bpr4 Paramecium tetraurelia Chromosome undetermined scaffold_12, whole genome shotgun sequence ,
parte-a0btv5 Paramecium tetraurelia Chromosome undetermined scaffold_128, whole genome shotgun sequence ,
parte-a0c3e0 Paramecium tetraurelia Chromosome undetermined scaffold_147, whole genome shotgun sequence ,
parte-a0dz74 Paramecium tetraurelia Chromosome undetermined scaffold_7, whole genome shotgun sequence ,
parte-a0e1p0 Paramecium tetraurelia Chromosome undetermined scaffold_73, whole genome shotgun sequence .
Hormone-sensitive_lipase_like :
parte-q6bgf1 Paramecium tetraurelia lipase, putative .
Monoglyceridelipase_lysophospholip :
parte-a0c962 Paramecium tetraurelia Chromosome undetermined scaffold_16, whole genome shotgun sequence ,
parte-a0crq3 Paramecium tetraurelia Chromosome undetermined scaffold_25, whole genome shotgun sequence ,
parte-a0cxu4 Paramecium tetraurelia Chromosome undetermined scaffold_30, whole genome shotgun sequence ,
parte-a0cyf3 Paramecium tetraurelia Chromosome undetermined scaffold_31, whole genome shotgun sequence ,
parte-a0czs5 Paramecium tetraurelia Chromosome undetermined scaffold_32, whole genome shotgun sequence ,
parte-a0dg79 Paramecium tetraurelia Chromosome undetermined scaffold_5, whole genome shotgun sequence ,
parte-a0diq2 Paramecium tetraurelia Chromosome undetermined scaffold_52, whole genome shotgun sequence ,
parte-a0dkh0 Paramecium tetraurelia Chromosome undetermined scaffold_54, whole genome shotgun sequence ,
parte-a0drp9 Paramecium tetraurelia Chromosome undetermined scaffold_60, whole genome shotgun sequence ,
parte-a0e0z4 Paramecium tetraurelia Chromosome undetermined scaffold_72, whole genome shotgun sequence .
PAF-Acetylhydrolase :
parte-a0d7k3 Paramecium tetraurelia. Uncharacterized protein .
Pectinacetylesterase-Notum :
parte-a0bnt1 Paramecium tetraurelia Chromosome undetermined scaffold_119, whole genome shotgun sequence ,
parte-a0c0q4 Paramecium tetraurelia Chromosome undetermined scaffold_140, whole genome shotgun sequence ,
parte-a0cqw8 Paramecium tetraurelia Chromosome undetermined scaffold_24, whole genome shotgun sequence ,
parte-a0d589 Paramecium tetraurelia Chromosome undetermined scaffold_38, whole genome shotgun sequence .
PPase_methylesterase_euk :
parte-a0cur9 Paramecium tetraurelia chromosome undetermined scaffold_28, whole genome shotgun sequence ,
parte-a0drx0 Paramecium tetraurelia chromosome undetermined scaffold_61, whole genome shotgun sequence ,
parte-a0e4m9 Paramecium tetraurelia Chromosome undetermined scaffold_78, whole genome shotgun sequence ,
parte-a0ef67 Paramecium tetraurelia Chromosome undetermined scaffold_93, whole genome shotgun sequence .
Prolylcarboxypeptidase :
parte-a0bz94 Paramecium tetraurelia Chromosome undetermined scaffold_139, whole genome shotgun sequence ,
parte-a0c0b8 Paramecium tetraurelia Chromosome undetermined scaffold_14, whole genome shotgun sequence ,
parte-a0c1z8 Paramecium tetraurelia Chromosome undetermined scaffold_143, whole genome shotgun sequence ,
parte-a0d9i7 Paramecium tetraurelia Chromosome undetermined scaffold_42, whole genome shotgun sequence ,
parte-a0de29 Paramecium tetraurelia Chromosome undetermined scaffold_47, whole genome shotgun sequence Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: parte-a0cb90 Colored MSA for Prolylcarboxypeptidase (raw)
MNKVFLISISLLLVMADDFSYNQKMYWFEHQLVDHYDKLNKNVFHQRYWV
VEENFVPETGVVLFQICGEYTCINDIKLRLFIIQLAKEFNALIIILEHRY
YGKSMPLGKESLKDENLRYLSTRQALDDLAYFQRFMVLNKKHGIKSQNPW
IAIGGSYPGALAAWYRYQYPHLVIGALASSAVVESITDFKMFDTQIFLSA
YKSGPQCAKDVQDMNKYAEQQILNQGTKEEFKRSFGAEKLTDLEFLFFFA
DAQLLIIQYGGRSELCKQLKDKSITEQIDYFRSVIEEGSYMEYGSYYLKN
DKYDENNLTPSRQWMYQCCSELGWWQTSPLNNSVRSTLIDIQFYKDFCNS
IFGGIRKNIFPDDQLANARFGGNELNVDNLIMTNGNEDPWKWSSVLVNQG
SILTYEINCENSGHCVELYTPKDEDCDQLKQARKDIISQFRKWIQDHYAS
IQ
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M N K V F L I S I S L L L V M A D D F S Y N Q K M Y W F E H Q L V D H Y D K L N K N V F H Q R Y W V V E E N F V P E T G V V L F Q I C G E Y T C I N D I K L R L F I I Q L A K E F N A L I I I L E H R Y Y G K S M P L G K E S L K D E N L R Y L S T R Q A L D D L A Y F Q R F M V L N K K H G I K S Q N P W I A I G G S Y P G A L A A W Y R Y Q Y P H L V I G A L A S S A V V E S I T D F K M F D T Q I F L S A Y K S G P Q C A K D V Q D M N K Y A E Q Q I L N Q G T K E E F K R S F G A E K L T D L E F L F F F A D A Q L L I I Q Y G G R S E L C K Q L K D K S I T E Q I D Y F R S V I E E G S Y M E Y G S Y Y L K N D K Y D E N N L T P S R Q W M Y Q C C S E L G W W Q T S P L N N S V R S T L I D I Q F Y K D F C N S I F G G I R K N I F P D D Q L A N A R F G G N E L N V D N L I M T N G N E D P W K W S S V L V N Q G S I L T Y E I N C E N S G H C V E L Y T P K D E D C D Q L K Q A R K D I I S Q F R K W I Q D H Y A S I Q
Reference
Title: Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraureliaAury JM , Jaillon O , Duret L , Noel B , Jubin C , Porcel BM , Segurens B , Daubin V , Anthouard V and Wincker P <33 more author(s)> Aury JM , Jaillon O , Duret L , Noel B , Jubin C , Porcel BM , Segurens B , Daubin V , Anthouard V , Aiach N , Arnaiz O , Billaut A , Beisson J , Blanc I , Bouhouche K , Camara F , Duharcourt S , Guigo R , Gogendeau D , Katinka M , Keller AM , Kissmehl R , Klotz C , Koll F , Le Mouel A , Lepere G , Malinsky S , Nowacki M , Nowak JK , Plattner H , Poulain J , Ruiz F , Serrano V , Zagulski M , Dessen P , Betermier M , Weissenbach J , Scarpelli C , Schachter V , Sperling L , Meyer E , Cohen J , Wincker P (- 33) Ref: Nature, 444 :171, 2006 : PubMed Abstract ESTHER: Aury_2006_Nature_444_171 PubMedSearch: Aury 2006 Nature 444 171 PubMedID: 17086204 Gene_locus related to this paper: parte-a0bds8 ,
parte-a0bga5 ,
parte-a0bnp2 ,
parte-a0bnt1 ,
parte-a0bpr4 ,
parte-a0btv5 ,
parte-a0byt1 ,
parte-a0bz94 ,
parte-a0c0b8 ,
parte-a0c0q4 ,
parte-a0c1z8 ,
parte-a0c3e0 ,
parte-a0c9f4 ,
parte-a0c962 ,
parte-a0cb90 ,
parte-a0cck1 ,
parte-a0cj40 ,
parte-a0cq13 ,
parte-a0cqw8 ,
parte-a0crq3 ,
parte-a0cu52 ,
parte-a0cur9 ,
parte-a0cxu4 ,
parte-a0cyf3 ,
parte-a0czs5 ,
parte-a0d1l8 ,
parte-a0d9i7 ,
parte-a0d589 ,
parte-a0de29 ,
parte-a0dem3 ,
parte-a0dg79 ,
parte-a0diq2 ,
parte-a0dk36 ,
parte-a0dkh0 ,
parte-a0dld4 ,
parte-a0dnw2 ,
parte-a0drp9 ,
parte-a0drx0 ,
parte-a0duj9 ,
parte-a0dvl0 ,
parte-a0dwm9 ,
parte-a0dy72 ,
parte-a0dz74 ,
parte-a0e0g8 ,
parte-a0e0z4 ,
parte-a0e1p0 ,
parte-a0e4m9 ,
parte-a0e8v9 ,
parte-a0e9r1 ,
parte-a0e581 ,
parte-a0ecy9 ,
parte-a0ecz4 ,
parte-a0ef67 ,
parte-a0d7k3 Abstract
The duplication of entire genomes has long been recognized as having great potential for evolutionary novelties, but the mechanisms underlying their resolution through gene loss are poorly understood. Here we show that in the unicellular eukaryote Paramecium tetraurelia, a ciliate, most of the nearly 40,000 genes arose through at least three successive whole-genome duplications. Phylogenetic analysis indicates that the most recent duplication coincides with an explosion of speciation events that gave rise to the P. aurelia complex of 15 sibling species. We observed that gene loss occurs over a long timescale, not as an initial massive event. Genes from the same metabolic pathway or protein complex have common patterns of gene loss, and highly expressed genes are over-retained after all duplications. The conclusion of this analysis is that many genes are maintained after whole-genome duplication not because of functional innovation but because of gene dosage constraints.
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