(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Bacteria: NE > FCB group: NE > Bacteroidetes/Chlorobi group: NE > Bacteroidetes: NE > Bacteroidia: NE > Bacteroidales: NE > Tannerellaceae: NE > Parabacteroides: NE > Parabacteroides distasonis: NE
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Parabacteroides distasonis ATCC 8503: N, E.
Parabacteroides sp. D13: N, E.
Molecular evidence
Database
No mutation 1 structure: 4Q34: Crystal structure of a putative esterase (BDI_1566) from Parabacteroides distasonis ATCC 8503 at 1.60 A resolution (CASP Target) No kinetic
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MRPVFILGIILLLVGCKQRDERVLMVDEQGSFAVGGTVLVDSLGHTFHGD HAYVFYQKPVGARKYPLVFAHGVGQFSKTWETTPDGREGFQNIFLRRRFC VYLVDQPRRGNAGRGTESVTISPAFDEEVWFNRFRVGIWPDYFEGVQFKR DKETLDQYFRQMTPTIGTTDFEVYSDAYAALFDKIGPGVFITHSQGGPVG WNTLLKTRNIKAIASYEPGGAVPFPEGQLPEEAKFITLSKKMEGIEVPMS VFMEYTKVPIVIYYGDNLPETDERPELYEWTRRLRLMKIWAKMLNDQGGD VTVIHLPEVGLHGNTHFPMSDLNNIEVADLLSEWLHTKALD
The adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. Little is known about the selective pressures that have shaped and are shaping this community's component species, which are dominated by members of the Bacteroidetes and Firmicutes divisions. To examine how the intestinal environment affects microbial genome evolution, we have sequenced the genomes of two members of the normal distal human gut microbiota, Bacteroides vulgatus and Bacteroides distasonis, and by comparison with the few other sequenced gut and non-gut Bacteroidetes, analyzed their niche and habitat adaptations. The results show that lateral gene transfer, mobile elements, and gene amplification have played important roles in affecting the ability of gut-dwelling Bacteroidetes to vary their cell surface, sense their environment, and harvest nutrient resources present in the distal intestine. Our findings show that these processes have been a driving force in the adaptation of Bacteroidetes to the distal gut environment, and emphasize the importance of considering the evolution of humans from an additional perspective, namely the evolution of our microbiomes.
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCT 11152) Parabacteroides sp. D13 Putative uncharacterized protein
