Mycobacterium tuberculosis, Mycobacterium bovis Rv3487c Carboxylesterase/phospholipase lipF
(from Uniprot) Hydrolyzes short-chain esters. Shows maximal activity with triacetin and p-nitrophenyl acetate. Has no enzyme activity on triacylglycerides or p-nitrophenyl esters (p-NP) with long fatty acids (tricaprin, p-NP caprylate, or p-NP caprate)\; experiments performed with enzyme missing the first 97 residues (PubMed:15939293). Has phospholipase C activity, making 1,2-DAG phosphocholine\; experiments performed with enzyme missing the first 97 residues. There are more than 3000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains
Family : Hormone-sensitive_lipase_like
Block : H
Position in NCBI Life Tree : Mycobacterium tuberculosis
VRAPGVRAAD GAGRVVLYLH GGAFVMCGPN SHSRIVNALS GFAESPVLIV DYRLIPKHSL GMALDDCHDA YQWLRARGYR PEQIVLAGDS AGGYLALALA QRLQCDDEKP AAIVAISPLL QLAKGPKQDH PNIGTDAMFP ARAFDALAAW VRAAAAKNMV DGRPEDLYEP LDHIESSLPP TLIHVSGSEV LLHDAQLGAG KLAAAGVCAE VRVWPGQAHL FQLATPLVPE ATRSLRQIGQ FIRDATADSS LSPVHRSRYV AGSPRAASRG AFGQSPI
Title : Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis - Zhang_2005_Protein.Expr.Purif_42_59 |
Author(s) : Zhang M , Wang JD , Li ZF , Xie J , Yang YP , Zhong Y , Wang HH |
Ref : Protein Expr Purif , 42 :59 , 2005 |
Abstract : Zhang_2005_Protein.Expr.Purif_42_59 |
ESTHER : Zhang_2005_Protein.Expr.Purif_42_59 |
PubMedSearch : Zhang_2005_Protein.Expr.Purif_42_59 |
PubMedID: 15939293 |
Gene_locus related to this paper: myctu-Rv3487c |
Title : Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis - Camacho_1999_Mol.Microbiol_34_257 |
Author(s) : Camacho LR , Ensergueix D , Perez E , Gicquel B , Guilhot C |
Ref : Molecular Microbiology , 34 :257 , 1999 |
Abstract : Camacho_1999_Mol.Microbiol_34_257 |
ESTHER : Camacho_1999_Mol.Microbiol_34_257 |
PubMedSearch : Camacho_1999_Mol.Microbiol_34_257 |
PubMedID: 10564470 |
Gene_locus related to this paper: myctu-Rv3487c |
Title : An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae - Philipp_1996_Proc.Natl.Acad.Sci.U.S.A_93_3132 |
Author(s) : Philipp WJ , Poulet S , Eiglmeier K , Pascopella L , Balasubramanian V , Heym B , Bergh S , Bloom BR , Jacobs WR, Jr. , Cole ST |
Ref : Proc Natl Acad Sci U S A , 93 :3132 , 1996 |
Abstract : Philipp_1996_Proc.Natl.Acad.Sci.U.S.A_93_3132 |
ESTHER : Philipp_1996_Proc.Natl.Acad.Sci.U.S.A_93_3132 |
PubMedSearch : Philipp_1996_Proc.Natl.Acad.Sci.U.S.A_93_3132 |
PubMedID: 8610181 |
Gene_locus related to this paper: myctu-Rv0217c , myctu-Rv0220 , myctu-Rv1076 , myctu-Rv1399c , myctu-Rv1400c , myctu-Rv1426c , myctu-Rv2045c , myctu-Rv2284 , myctu-Rv2385 , myctu-Rv2485c , myctu-Rv2970c , myctu-Rv3084 , myctu-Rv3097c , myctu-Rv3487c |