Gene_Locus Report
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Gene_locus Report for: mouse-apeh

Mus musculus (Mouse) hydrolase) (aph) (acylaminoacyl-peptidase)

Relationship
Family|ACPH_Peptidase_S9
Block| X
Position in NCBI Life Tree|Mus musculus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Myomorpha: N E > Muroidea: N E > Muridae: N E > Murinae: N E > Mus [genus]: N E > Mus [subgenus]: N E > Mus musculus: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
2 inhibitors: ABP-C6, NBD-HE-HP
>3 Genbank links 2 more: BC025494, BC026594, BC034199
1 UniProt : Q8R146
1 UniProt : Q8R146
1 Interpro : Q8R146
1 Pfam : Q8R146
1 PIRSF : Q8R146
1 SUPERFAM : Q8R146
1 MGD : 88041
1 ENSEMBL : ENSMUSG00000032590
Sequence
Peptide
Graphical view for this peptide sequence: mouse-apeh
Colored MSA for ACPH_Peptidase_S9 (raw) 
MERQVLLSEPQEAAALYRGLSRQPSLSAACLGPEVTTQYGGLYRTVHTEW
TQRDLDRMENIRFCRQYLVFHDGDSVVFAGPAGNSVETPGELLSRESPSG
TMKAVLRKAGGAVSGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCF
GCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVSASDEEMARPKKPDQA
IKGDQFVFYEDWGETMVSKSIPVLCVLDIESGNISVLEGVPENVSPGQAF
WAPGDTGVVFVGWWHEPFRLGIRYCTNRRSALYYVDLSGGKCELLSDESL
AVCSPRLSPDQCRVVYLQYPSLAPHHQCSQLFLYDWYTKVTSLVVDIVPR
QLGESFSGIYCSLLPLGCWSADSQRVVFDSVQRSRQDLFAVDTQTGSVTS
LTAGGSAGSWKLLTIDRDLMVAQFSTPNLPPSLKVGFLPPAGKEQSVSWV
SLEEAEPIPDIHWGIRVLHPPPDQENVQYADLDFEAILLQPSNSPDKSQV
PMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILS
LPGNVGHQDVKDVQFAVQQVLQEEHFDARRVALMGGSHGGFLSCHLIGQY
PETYSACIARNPVINIVSMMGTTDIPDWCMVETGFPYSNDYLPDLNVLEE
MLDKSPIKYIPQVKTPVLLMLGQEDRRVPFKQGLEYYHALKARNVPVRLL
LYPKSTHALSEVEVESDSFMNTVLWLHTHLGS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA
MERQVLLSEPQEAAALYRGLSRQPSLSAACLGPEVTTQYGGLYRTVHTEW
TQRDLDRMENIRFCRQYLVFHDGDSVVFAGPAGNSVETPGELLSRESPSG
TMKAVLRKAGGAVSGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCF
GCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVSASDEEMARPKKPDQA
IKGDQFVFYEDWGETMVSKSIPVLCVLDIESGNISVLEGVPENVSPGQAF
WAPGDTGVVFVGWWHEPFRLGIRYCTNRRSALYYVDLSGGKCELLSDESL
AVCSPRLSPDQCRVVYLQYPSLAPHHQCSQLFLYDWYTKVTSLVVDIVPR
QLGESFSGIYCSLLPLGCWSADSQRVVFDSVQRSRQDLFAVDTQTGSVTS
LTAGGSAGSWKLLTIDRDLMVAQFSTPNLPPSLKVGFLPPAGKEQSVSWV
SLEEAEPIPDIHWGIRVLHPPPDQENVQYADLDFEAILLQPSNSPDKSQV
PMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILS
LPGNVGHQDVKDVQFAVQQVLQEEHFDARRVALMGGSHGGFLSCHLIGQY
PETYSACIARNPVINIVSMMGTTDIPDWCMVETGFPYSNDYLPDLNVLEE
MLDKSPIKYIPQVKTPVLLMLGQEDRRVPFKQGLEYYHALKARNVPVRLL
LYPKSTHALSEVEVESDSFMNTVLWLHTHLGS


No Reference
Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
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