Mus musculus (Mouse) triacylglycerol hydrolase (tgh) Fatty acid ethyl ester synthase Carboxylesterase 3 (EC 3.1.1.1)
old human-hBr3 Genbank AB025028 Mori et al. WARNING this human sequence in database is soo close to mouse-Ces1d, not found in genome so is it a contamination or a file error? The human ortholog of mouse Ces3\/TGH\/Ces1d is CES1
MRLYPLIWLS LAACTAWGYP SSPPVVNTVK GKVLGKYVNL EGFTQPVAVF LGVPFAKPPL GSLRFAPPQP AEPWSFVKNT TSYPPMCSQD AVGGQVLSEL FTNRKENIPL QFSEDCLYLN IYTPADLTKN SRLPVMVWIH GGGLVVGGAS TYDGLALSAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW VQDNIANFGG NPGSVTIFGE SAGGFSVSVL VLSPLAKNLF HRAISESGVS LTAALITTDV KPIAGLVATL SGCKTTTSAV MVHCLRQKTE DELLETSLKL NLFKLDLLGN PKESYPFLPT VIDGVVLPKA PEEILAEKSF STVPYIVGIN KQEFGWIIPT LMGYPLAEGK LDQKTANSLL WKSYPTLKIS ENMIPVVAEK YLGGTDDLTK KKDLFQDLMA DVVFGVPSVI VSRSHRDAGA STYMYEFEYR PSFVSAMRPK AVIGDHGDEI FSVFGSPFLK DGASEEETNL SKMVMKFWAN FARNGNPNGG GLPHWPEYDQ KEGYLKIGAS TQAAQRLKDK EVSFWAELRA KESAQRPSHR EHVEL
Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618 |
Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH |
Ref : Acta Pharm Sin B , 13 :618 , 2023 |
Abstract : Gan_2023_Acta.Pharm.Sin.B_13_618 |
ESTHER : Gan_2023_Acta.Pharm.Sin.B_13_618 |
PubMedSearch : Gan_2023_Acta.Pharm.Sin.B_13_618 |
PubMedID: 36873183 |
Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h |
Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956 |
Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH |
Ref : Biomed Pharmacother , 164 :114956 , 2023 |
Abstract : Gan_2023_Biomed.Pharmacother_164_114956 |
ESTHER : Gan_2023_Biomed.Pharmacother_164_114956 |
PubMedSearch : Gan_2023_Biomed.Pharmacother_164_114956 |
PubMedID: 37267638 |
Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e |
Title : Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice - Li_2022_Life.Sci.Alliance_5_ |
Author(s) : Li G , Li X , Yang L , Wang S , Dai Y , Fekry B , Veillon L , Tan L , Berdeaux R , Eckel-Mahan K , Lorenzi PL , Zhao Z , Lehner R , Sun K |
Ref : Life Sciences Alliance , 5 : , 2022 |
Abstract : Li_2022_Life.Sci.Alliance_5_ |
ESTHER : Li_2022_Life.Sci.Alliance_5_ |
PubMedSearch : Li_2022_Life.Sci.Alliance_5_ |
PubMedID: 35459739 |
Gene_locus related to this paper: mouse-Ces1d |
Title : Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver - Lian_2021_J.Lipid.Res__100093 |
Author(s) : Lian J , van der Veen JN , Watts R , Jacobs RL , Lehner R |
Ref : J Lipid Res , :100093 , 2021 |
Abstract : Lian_2021_J.Lipid.Res__100093 |
ESTHER : Lian_2021_J.Lipid.Res__100093 |
PubMedSearch : Lian_2021_J.Lipid.Res__100093 |
PubMedID: 34153284 |
Gene_locus related to this paper: mouse-Ces1d |
Title : A Unique Role of Carboxylesterase 3 (Ces3) in beta-Adrenergic Signaling-Stimulated Thermogenesis - Yang_2019_Diabetes_68_1178 |
Author(s) : Yang L , Li X , Tang H , Gao Z , Zhang K , Sun K |
Ref : Diabetes , 68 :1178 , 2019 |
Abstract : Yang_2019_Diabetes_68_1178 |
ESTHER : Yang_2019_Diabetes_68_1178 |
PubMedSearch : Yang_2019_Diabetes_68_1178 |
PubMedID: 30862682 |
Gene_locus related to this paper: human-CES3 , mouse-Ces1d |
Title : Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation - Lian_2019_J.Lipid.Res_60_880 |
Author(s) : Lian J , Watts R , Quiroga AD , Beggs MR , Alexander RT , Lehner R |
Ref : J Lipid Res , 60 :880 , 2019 |
Abstract : Lian_2019_J.Lipid.Res_60_880 |
ESTHER : Lian_2019_J.Lipid.Res_60_880 |
PubMedSearch : Lian_2019_J.Lipid.Res_60_880 |
PubMedID: 30737251 |
Gene_locus related to this paper: mouse-Ces1d |
Title : Ces3\/TGH Deficiency Attenuates Steatohepatitis - Lian_2016_Sci.Rep_6_25747 |
Author(s) : Lian J , Wei E , Groenendyk J , Das SK , Hermansson M , Li L , Watts R , Thiesen A , Oudit GY , Michalak M , Lehner R |
Ref : Sci Rep , 6 :25747 , 2016 |
Abstract : Lian_2016_Sci.Rep_6_25747 |
ESTHER : Lian_2016_Sci.Rep_6_25747 |
PubMedSearch : Lian_2016_Sci.Rep_6_25747 |
PubMedID: 27181051 |
Gene_locus related to this paper: mouse-Ces1d |
Title : Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes - Dominguez_2014_Nat.Chem.Biol_10_113 |
Author(s) : Dominguez E , Galmozzi A , Chang JW , Hsu KL , Pawlak J , Li W , Godio C , Thomas J , Partida D , Niessen S , O'Brien PE , Russell AP , Watt MJ , Nomura DK , Cravatt BF , Saez E |
Ref : Nat Chemical Biology , 10 :113 , 2014 |
Abstract : Dominguez_2014_Nat.Chem.Biol_10_113 |
ESTHER : Dominguez_2014_Nat.Chem.Biol_10_113 |
PubMedSearch : Dominguez_2014_Nat.Chem.Biol_10_113 |
PubMedID: 24362705 |
Gene_locus related to this paper: human-CES3 , mouse-Ces1d |
Title : Liver-specific cholesteryl ester hydrolase deficiency attenuates sterol elimination in the feces and increases atherosclerosis in ldlr-\/- mice - Bie_2013_Arterioscler.Thromb.Vasc.Biol_33_1795 |
Author(s) : Bie J , Wang J , Marqueen KE , Osborne R , Kakiyama G , Korzun W , Ghosh SS , Ghosh S |
Ref : Arterioscler Thromb Vasc Biol , 33 :1795 , 2013 |
Abstract : Bie_2013_Arterioscler.Thromb.Vasc.Biol_33_1795 |
ESTHER : Bie_2013_Arterioscler.Thromb.Vasc.Biol_33_1795 |
PubMedSearch : Bie_2013_Arterioscler.Thromb.Vasc.Biol_33_1795 |
PubMedID: 23744992 |
Gene_locus related to this paper: mouse-Ces1d |
Title : Ces3\/TGH deficiency improves dyslipidemia and reduces atherosclerosis in Ldlr(-\/-) mice - Lian_2012_Circ.Res_111_982 |
Author(s) : Lian J , Quiroga AD , Li L , Lehner R |
Ref : Circulation Research , 111 :982 , 2012 |
Abstract : Lian_2012_Circ.Res_111_982 |
ESTHER : Lian_2012_Circ.Res_111_982 |
PubMedSearch : Lian_2012_Circ.Res_111_982 |
PubMedID: 22872154 |
Gene_locus related to this paper: mouse-Ces1d |
Title : Isolation and characterization of a microsomal acid retinyl ester hydrolase - Linke_2005_J.Biol.Chem_280_23287 |
Author(s) : Linke T , Dawson H , Harrison EH |
Ref : Journal of Biological Chemistry , 280 :23287 , 2005 |
Abstract : Linke_2005_J.Biol.Chem_280_23287 |
ESTHER : Linke_2005_J.Biol.Chem_280_23287 |
PubMedSearch : Linke_2005_J.Biol.Chem_280_23287 |
PubMedID: 15767260 |
Gene_locus related to this paper: mouse-Ces1d , ratno-Ces1d |
Title : Identification of di-(2-ethylhexyl) phthalate-induced carboxylesterase 1 in C57BL\/6 mouse liver microsomes: purification, cDNA cloning, and baculovirus-mediated expression - Furihata_2004_Drug.Metab.Dispos_32_1170 |
Author(s) : Furihata T , Hosokawa M , Koyano N , Nakamura T , Satoh T , Chiba K |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 32 :1170 , 2004 |
Abstract : Furihata_2004_Drug.Metab.Dispos_32_1170 |
ESTHER : Furihata_2004_Drug.Metab.Dispos_32_1170 |
PubMedSearch : Furihata_2004_Drug.Metab.Dispos_32_1170 |
PubMedID: 15269189 |
Gene_locus related to this paper: mouse-Ces1d |
Title : Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase - Soni_2004_J.Biol.Chem_279_40683 |
Author(s) : Soni KG , Lehner R , Metalnikov P , O'Donnell P , Semache M , Gao W , Ashman K , Pshezhetsky AV , Mitchell GA |
Ref : Journal of Biological Chemistry , 279 :40683 , 2004 |
Abstract : Soni_2004_J.Biol.Chem_279_40683 |
ESTHER : Soni_2004_J.Biol.Chem_279_40683 |
PubMedSearch : Soni_2004_J.Biol.Chem_279_40683 |
PubMedID: 15220344 |
Gene_locus related to this paper: mouse-Ces1d |
Title : The cloning and expression of a murine triacylglycerol hydrolase cDNA and the structure of its corresponding gene - Dolinsky_2001_Biochim.Biophys.Acta_1532_162 |
Author(s) : Dolinsky VW , Sipione S , Lehner R , Vance DE |
Ref : Biochimica & Biophysica Acta , 1532 :162 , 2001 |
Abstract : Dolinsky_2001_Biochim.Biophys.Acta_1532_162 |
ESTHER : Dolinsky_2001_Biochim.Biophys.Acta_1532_162 |
PubMedSearch : Dolinsky_2001_Biochim.Biophys.Acta_1532_162 |
PubMedID: 11470237 |
Gene_locus related to this paper: mouse-Ces1d |
Title : cDNA cloning, characterization and stable expression of novel human brain carboxylesterase - Mori_1999_FEBS.Lett_458_17 |
Author(s) : Mori M , Hosokawa M , Ogasawara Y , Tsukada E , Chiba K |
Ref : FEBS Letters , 458 :17 , 1999 |
Abstract : Mori_1999_FEBS.Lett_458_17 |
ESTHER : Mori_1999_FEBS.Lett_458_17 |
PubMedSearch : Mori_1999_FEBS.Lett_458_17 |
PubMedID: 10518925 |
Gene_locus related to this paper: human-CES1 , mouse-Ces1d |