Gene_Locus Report

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Gene_locus Report for: manse-hyep

Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) juvenile hormone-specific epoxide hydrolase (EC 3.3.2.3)

Relationship
Family|Epoxide_hydrolase
Block| X
Position in NCBI Life Tree|Manduca sexta
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Amphiesmenoptera: N E > Lepidoptera: N E > Glossata: N E > Neolepidoptera: N E > Heteroneura: N E > Ditrysia: N E > Obtectomera: N E > Bombycoidea: N E > Sphingidae: N E > Sphinginae: N E > Sphingini: N E > Manduca: N E > Manduca sexta: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : U46682
1 UniProt : Q25489
1 UniProt : Q25489
1 Interpro : Q25489
1 Pfam : Q25489
1 PIRSF : Q25489
1 SUPERFAM : Q25489
Sequence
Graphical view for this peptide sequence: manse-hyep
Colored MSA for Epoxide_hydrolase (raw)
MYKILSSFVAGVAIGSGLVITYVLYNVPEPPELDLQRWWGIGTRPTEEDK
SIRPFSIDFNDTVILDLKERLKNRRPFTKPLEGINSEYGMNTEYLETVLE
YWLNEYNFKKRAELLNKFPHYKTRIQGLDLHFIRVKPEIKEGVQVLPLLM
MHGWPSSSKEFDKVIPILTTPKHEYNIVFEVVAVDLPGYGFSEGTNKPGL
NPVQIGVMMRNLMLRLGFEKFYIQAGDWGSQCATHMATLFPDQVLGLHTN
MPLSSRPLSTVKLFIGALFPSLIVDAKYMDRIYPLKNLFSYILRETGYFH
IQATKPDTIGVALTDSPAGLAGYLIEKMAICSNRDQLDTPHGGLENLNLD
DVLDTVTINWINNCIVTSTRLYAEGFSWPEVLIVHRIPSMVPTAGINFKY
EVLYQPDWILRDKFPNLVRSTVLDFGGHFAALHTPQALADDIFASAVQFL
KFHDRKRNQKSS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MYKILSSFVAGVAIGSGLVITYVLYNVPEPPELDLQRWWGIGTRPTEEDK
SIRPFSIDFNDTVILDLKERLKNRRPFTKPLEGINSEYGMNTEYLETVLE
YWLNEYNFKKRAELLNKFPHYKTRIQGLDLHFIRVKPEIKEGVQVLPLLM
MHGWPSSSKEFDKVIPILTTPKHEYNIVFEVVAVDLPGYGFSEGTNKPGL
NPVQIGVMMRNLMLRLGFEKFYIQAGDWGSQCATHMATLFPDQVLGLHTN
MPLSSRPLSTVKLFIGALFPSLIVDAKYMDRIYPLKNLFSYILRETGYFH
IQATKPDTIGVALTDSPAGLAGYLIEKMAICSNRDQLDTPHGGLENLNLD
DVLDTVTINWINNCIVTSTRLYAEGFSWPEVLIVHRIPSMVPTAGINFKY
EVLYQPDWILRDKFPNLVRSTVLDFGGHFAALHTPQALADDIFASAVQFL
KFHDRKRNQKSS


Reference
    Title: An insect juvenile hormone-specific epoxide hydrolase is related to vertebrate microsomal epoxide hydrolases.
    Wojtasek H, Prestwich GD
    Ref: Biochemical & Biophysical Research Communications, 220:323, 1996 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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