Gene_locus Report for: lepmj-e5aau5 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > dothideomyceta: N E > Dothideomycetes: N E > Pleosporomycetidae: N E > Pleosporales: N E > Pleosporineae: N E > Leptosphaeriaceae: N E > Leptosphaeria: N E > Leptosphaeria maculans species complex: N E > Leptosphaeria maculans: N E ABHD11-Acetyl_transferase :
lepmj-e5ab81 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam). Putative uncharacterized protein .
ABHD13-BEM46 :
lepmj-e4zg43 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam). Similar to BEM46 family protein .
abh_upf0017 :
lepmj-e5a0i2 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to medium-chain fatty acid ethyl ester synthase/esterase 1 .
Acetylxylan_esterase :
lepmj-e4zxp4 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein ,
lepmj-e4zpy5 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to acetylxylan esterase ,
lepmj-e5ae17 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein .
Acidic_Lipase :
lepmj-e4zx66 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to ab-hydrolase associated lipase ,
lepmj-e5acd1 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein .
Arb2_domain :
lepmj-e4zgy1 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam). Uncharacterized protein .
Canar_LipB :
lepmj-e4ziv2 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to lipase .
Carboxypeptidase_S10 :
lepmj-kex1 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam). Carboxypeptidase D ,
lepmj-cbpya Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam). Carboxypeptidase Y homolog A .
Cutinase :
lepmj-e5a4g5 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein ,
lepmj-e4zhg2 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to gi|157830726|pdb|1CUA|A Chain A ,
lepmj-e4zuw5 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein ,
lepmj-e5a2e0 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein ,
lepmj-e4zpv2 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein .
DPP4N_Peptidase_S9 :
lepmj-e4zqu4 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to dipeptidyl-peptidase IV ,
lepmj-e4zvl4 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein .
Fungal_carboxylesterase_lipase :
lepmc-e4zk57 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein Lema_P071600.1 ,
lepmc-e4zpw3 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to triacylglycerol lipase ,
lepmc-e4ztn0 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein Lema_P118890.1 ,
lepmc-e4zuu8 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carboxylesterase ,
lepmc-e4zvu7 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to lipase ,
lepmc-e4zw27 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carboxylesterase ,
lepmc-e4zxh2 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein Lema_P025340.1 ,
lepmc-e5a0g9 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carotenoid ester lipase ,
lepmc-e5a0p6 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to lipase ,
lepmc-e5a0w9 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to lipase II ,
lepmc-e5a1r8 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to triacylglycerol lipase ,
lepmc-e5a4k0 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carotenoid ester lipase ,
lepmc-e5a5b3 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to lipase ,
lepmc-e5a8w2 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carboxylesterase family protein ,
lepmc-e5a9d7 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein Lema_P014080.1 ,
lepmc-e5a9q5 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein Lema_P015260.1 ,
lepmc-e5a396 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carboxylesterase family protein ,
lepmc-e5a700 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to carboxylesterase ,
lepmc-e5afs8 Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Similar to lipase .
Fusarinine_C_esterase_sidJ :
lepmj-e5a510 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein .
Glucuronoyl_esterase :
lepmj-e4zh04 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Predicted protein .
PPase_methylesterase_euk :
lepmj-e4zvh3 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Protein phosphatase methylesterase 1 .
Proline_iminopeptidase :
lepmj-e5a374 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam). Similar to prolyl aminopeptidase .
Prolylcarboxypeptidase :
lepmj-e4ziv6 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Similar to serine peptidase ,
lepmj-e4zju4 Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / rac Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) Putative uncharacterized protein .
Thioesterase :
lepmc-q6q891 Leptosphaeria maculans (Blackleg fungus) pks1 Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: lepmj-e5aau5 Colored MSA for Glucuronoyl_esterase (raw)
MKYSIILPFLATTVLTAPVLEQRQDNVCTVPTTFPTTANAKLPNPFKFFD
GRDVKTKADFDCKNQEVSAAMQAQELGDFPKKPSSVTATFSGSSLSITST
EGGKSVSFSVSIKKPSGAGPFPAIIAYGAASIPVPANVATITFNNDEIGQ
QQGGNSRGKGKFFDLYGSSHSAGALTAWAWGVDRIIDALEITPAAGIDPK
FVGVTGCSRNGKGAFVAAALVKRIALGLPQESGAGGAACWRISDSEKAKG
KNIQTSSQIVGENVWFSTRFNAFSTKASTTSTDHHQLAGMVAPRGLLVIE
NEIDWLGPVSTTACMKAGRLIYKALGVPDNMGLTGSGNHNHCSFPSNQQT
ELTAFINKFLLGQSSNTANIEKGPSGADAATYIDWTAPTLS
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M K Y S I I L P F L A T T V L T A P V L E Q R Q D N V C T V P T T F P T T A N A K L P N P F K F F D G R D V K T K A D F D C K N Q E V S A A M Q A Q E L G D F P K K P S S V T A T F S G S S L S I T S T E G G K S V S F S V S I K K P S G A G P F P A I I A Y G A A S I P V P A N V A T I T F N N D E I G Q Q Q G G N S R G K G K F F D L Y G S S H S A G A L T A W A W G V D R I I D A L E I T P A A G I D P K F V G V T G C S R N G K G A F V A A A L V K R I A L G L P Q E S G A G G A A C W R I S D S E K A K G K N I Q T S S Q I V G E N V W F S T R F N A F S T K A S T T S T D H H Q L A G M V A P R G L L V I E N E I D W L G P V S T T A C M K A G R L I Y K A L G V P D N M G L T G S G N H N H C S F P S N Q Q T E L T A F I N K F L L G Q S S N T A N I E K G P S G A D A A T Y I D W T A P T L S
Reference
Title: Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutationsRouxel T , Grandaubert J , Hane JK , Hoede C , van de Wouw AP , Couloux A , Dominguez V , Anthouard V , Bally P and Howlett BJ <31 more author(s)> Rouxel T , Grandaubert J , Hane JK , Hoede C , van de Wouw AP , Couloux A , Dominguez V , Anthouard V , Bally P , Bourras S , Cozijnsen AJ , Ciuffetti LM , Degrave A , Dilmaghani A , Duret L , Fudal I , Goodwin SB , Gout L , Glaser N , Linglin J , Kema GH , Lapalu N , Lawrence CB , May K , Meyer M , Ollivier B , Poulain J , Schoch CL , Simon A , Spatafora JW , Stachowiak A , Turgeon BG , Tyler BM , Vincent D , Weissenbach J , Amselem J , Quesneville H , Oliver RP , Wincker P , Balesdent MH , Howlett BJ (- 31) Ref: Nat Commun, 2 :202, 2011 : PubMed Abstract ESTHER: Rouxel_2011_Nat.Commun_2_202 PubMedSearch: Rouxel 2011 Nat.Commun 2 202 PubMedID: 21326234 Gene_locus related to this paper: lepmc-q6q891 ,
lepmj-e4zh04 ,
lepmj-e4ziv6 ,
lepmj-e4zju4 ,
lepmj-e4zqu4 ,
lepmj-e4zvh3 ,
lepmj-e4zvl4 ,
lepmj-e4zx66 ,
lepmj-e5a0i2 ,
lepmj-e5a510 ,
lepmj-e5aau5 ,
lepmj-e5acd1 ,
lepmj-e5a4g5 ,
lepmj-e4zhg2 ,
lepmj-e4zuw5 ,
lepmj-e5a2e0 ,
lepmj-e4zpv2 ,
lepmj-e4zxp4 ,
lepmj-e4zpy5 ,
lepmj-e5ae17 ,
lepmj-e4ziv2 ,
lepmj-e5a374 ,
lepmj-e5ab81 ,
lepmj-e4zgy1 ,
lepmj-e4zg43 ,
lepmj-kex1 ,
lepmj-cbpya Abstract
Fungi are of primary ecological, biotechnological and economic importance. Many fundamental biological processes that are shared by animals and fungi are studied in fungi due to their experimental tractability. Many fungi are pathogens or mutualists and are model systems to analyse effector genes and their mechanisms of diversification. In this study, we report the genome sequence of the phytopathogenic ascomycete Leptosphaeria maculans and characterize its repertoire of protein effectors. The L. maculans genome has an unusual bipartite structure with alternating distinct guanine and cytosine-equilibrated and adenine and thymine (AT)-rich blocks of homogenous nucleotide composition. The AT-rich blocks comprise one-third of the genome and contain effector genes and families of transposable elements, both of which are affected by repeat-induced point mutation, a fungal-specific genome defence mechanism. This genomic environment for effectors promotes rapid sequence diversification and underpins the evolutionary potential of the fungus to adapt rapidly to novel host-derived constraints.
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