(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Bacteria: NE > Terrabacteria group: NE > Firmicutes: NE > Bacilli: NE > Lactobacillales: NE > Lactobacillaceae: NE > Lactobacillus: NE > Lactobacillus brevis: NE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MRNQQFAIRPTTLDQARVELQQIHFLDDTNLSFTTPSDLLRDFYDRSWPE YTTSSVVAQQLSNLMATPETDGLTYLTTHEQVPVDVFYNLALQRLGFAVD LDFQLTDPLAAMTKIQLPVADHEGTTFTLNELMNAWYVLLTTHNKTGQTF LDQLTTHGYFAPLIHDNSVPKPLIFNGKAQAVFDTTQLIHEVVYVESPQD TDHDGHRDLLKAEIIRPAETANGLKVPVLYTASPYNQGTNDEAGEALTHN VNVPLTAKQPAATTLADVTAESVTTPLPDARPVTATTHTAAETFAREQSY TLNDYFLARGFAVVYAAGIGTKDSDGLRTTGDPEETTSTIAIIEWLAGNR TAFTTRNATQAIPAWWSNHQVAMTGRSYLGTLATAAATTGVAGLKTVISE AAISNWYDYYRDGGLVVAPGGFPGEDADVLAEETFSRQLLAGDYHRIQEK WQHQLAAITQNQDRVTGNYNRFWDARNYLKNAKNIKADLLLVHGLNDWNV KPRNVNNLWRAVRDLPVTKKLILHQGQHIYINAFRSIDYTDIVNLWLTHE LLGVDNHAETLLPNVIIQDNVTPETWQAYPDWDAPSNPVQHFNLQADELV APSDHIPAAATSFNDQLPVDQFNHYTHHIDEWQADLLGDKHNAMFKHRLL FKSAVLTDDLVLDGRPTIDLQVAVNQPLGLLSFQLVDYGDAKRLGVSPTP LRIRLDEGYRWREDNLREFTVAATTPWKMITKGHRNLQNRTNAYQVDELK PNTFYDLSVTLQPTHYRLLAGHQLGLVIYATDFGMTVRGNQDLQYSIQLG QSALHVPFITD
Lactic acid-producing bacteria are associated with various plant and animal niches and play a key role in the production of fermented foods and beverages. We report nine genome sequences representing the phylogenetic and functional diversity of these bacteria. The small genomes of lactic acid bacteria encode a broad repertoire of transporters for efficient carbon and nitrogen acquisition from the nutritionally rich environments they inhabit and reflect a limited range of biosynthetic capabilities that indicate both prototrophic and auxotrophic strains. Phylogenetic analyses, comparison of gene content across the group, and reconstruction of ancestral gene sets indicate a combination of extensive gene loss and key gene acquisitions via horizontal gene transfer during the coevolution of lactic acid bacteria with their habitats.
