Gene_locus Report for: horse-f6q1u3 Equus caballus (Horse). Abhydrolase domain containing 8
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Laurasiatheria: N E > Perissodactyla: N E > Equidae: N E > Equus [genus]: N E > Equus [subgenus]: N E > Equus caballus: N E ABHD6-Lip :
horse-f7bvl6 Equus caballus (Horse) Uncharacterized protein .
ABHD10 :
horse-f6zna7 Equus caballus (Horse). Abhydrolase domain containing 10 .
ABHD11-Acetyl_transferase :
horse-f6xa70 Equus caballus (Horse). Abhydrolase domain containing 11 .
ABHD12-PHARC :
horse-f6x5e5 Equus caballus (Horse) Uncharacterized protein ,
horse-f7adj7 Equus caballus (Horse). Uncharacterized protein .
ABHD13-BEM46 :
horse-f7d8t6 Equus caballus (Horse). Abhydrolase domain containing 13 .
ABHD16 :
horse-f7bm46 Equus caballus (Horse). Abhydrolase domain containing 16A .
ABHD18 :
horse-f6s101 Equus caballus (Horse). ABHD18 Uncharacterized protein .
abh_upf0017 :
horse-f6wgf3 Equus caballus (Horse). Abhydrolase domain containing 15 .
ACHE :
horse-ACHE Equus caballus, Horse acetylcholinesterase .
Arb2_FAM172A :
horse-f7cuh0 Equus caballus (Horse). Family with sequence similarity 172 member A .
Arylacetamide_deacetylase :
horse-f6r609 Equus caballus (Horse). Uncharacterized protein ,
horse-f6y0j2 Equus caballus (Horse). Uncharacterized protein ,
horse-f6zvb2 Equus caballus (Horse). Uncharacterized protein ,
horse-f7e4g0 Equus caballus (Horse). Uncharacterized protein .
BCHE :
horse-BCHE Equus caballus, Horse butyrylcholinesterase .
Carb_B_Chordata :
horse-f6pri5 Equus caballus (Horse) Uncharacterized protein ,
horse-f6qlk6 Equus caballus (Horse) Uncharacterized protein ,
horse-f6un85 Equus caballus (Horse) Uncharacterized protein ,
horse-f6vxp7 Equus caballus (Horse) liver carboxylesterase 1 ,
horse-f6zmg7 Equus caballus (Horse) Uncharacterized protein ,
horse-f7bj10 Equus caballus (Horse) Uncharacterized protein ,
horse-f7c7a8 Equus caballus (Horse) Uncharacterized protein .
Cholesterol_esterase :
horse-f7agv7 Equus caballus (Horse) Uncharacterized protein .
CIB-CCG1-interacting-factor-B :
horse-f6wfs9 Equus caballus (Horse) Uncharacterized protein ,
horse-f7bk45 Equus caballus (Horse) Uncharacterized protein .
CMBL :
horse-f6ul42 Equus caballus (Horse). Carboxymethylenebutenolidase homolog .
FSH1 :
horse-f6qj19 Equus caballus (Horse). OVCA2, serine hydrolase domain containing .
Hepatic_Lipase :
horse-f6ti02 Equus caballus (Horse). Lipase C, hepatic type .
Kynurenine-formamidase :
horse-f6wfa7 Equus caballus (Horse). N-formylkynurenine formamidase .
Lipase_3 :
horse-f6tq73 Equus caballus (Horse). Diacylglycerol lipase alpha .
Lipoprotein_Lipase :
horse-f6quf7 Equus caballus (Horse). Lipoprotein lipase ,
horse-f6tn81 Equus caballus (Horse). Lipase G, endothelial type .
Maspardin-ACP33-SPG21_like :
horse-f6sfg0 Equus caballus (Horse) Uncharacterized protein .
Monoglyceridelipase_lysophospholip :
horse-f7cpx3 Equus caballus (Horse). Uncharacterized protein .
Ndr_family :
horse-f6ut17 Equus caballus (Horse) Uncharacterized protein ,
horse-f6svq9 Equus caballus (Horse) Uncharacterized protein ,
horse-f6xgj6 Equus caballus (Horse) Uncharacterized protein .
Neuroligin :
horse-f6uif6 Equus caballus (Horse) Uncharacterized protein ,
horse-f6x0i7 Equus caballus (Horse) Uncharacterized protein ,
horse-f7cxj0 Equus caballus (Horse) Uncharacterized protein .
NLS3-Tex30 :
horse-f6wzv8 Equus caballus (Horse) Uncharacterized protein ,
horse-f7afw6 Equus caballus (Horse) Uncharacterized protein .
Pancreatic_lipase :
horse-1plip ,
horse-2plrp ,
horse-f6re01 Equus caballus (Horse). Pancreatic lipase ,
horse-f6xmp6 Equus caballus (Horse). Pancreatic lipase .
Pectinacetylesterase-Notum :
horse-f7cdt1 Equus caballus (Horse) Uncharacterized protein .
Phospholipase :
horse-f6vts1 Equus caballus (Horse). Phospholipase A1 member A ,
horse-f7am73 Equus caballus (Horse). Lipase H ,
horse-f7dme2 Equus caballus (Horse). Lipase I .
SERHL :
horse-f6q208 Equus caballus (Horse). Serine hydrolase like 2 .
Thyroglobulin :
horse-f6qsc5 Equus caballus (Horse) Uncharacterized protein .
Valacyclovir-hydrolase :
horse-f6r958 Equus caballus (Horse) Uncharacterized protein Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: horse-f6q1u3 Colored MSA for ABHD8 (raw)
MLTGVTGGIFCCLLGAPPNAVGPLESVESSDGYTFVEVKPGRVLRVKHAG
PAPAPNPPPPLPDAAHGDQSGLVRCQRRITVYRNGRLLVENLGPAPRADL
LHGQNGSGEPPATLEVELADPAGSAGRVGPTSAGSGGGGRRRRARRPKRT
ILIDCEKRITSCKGTQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVA
PDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSF
CTFLAHEYPDLVHKVIMINGGGPTALEPSFCSIFNMPTCVLHCLSPCLAW
SFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAE
LTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPET
VNTLLHEFLLWEPEPAPKALPAPPEEK
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M L T G V T G G I F C C L L G A P P N A V G P L E S V E S S D G Y T F V E V K P G R V L R V K H A G P A P A P N P P P P L P D A A H G D Q S G L V R C Q R R I T V Y R N G R L L V E N L G P A P R A D L L H G Q N G S G E P P A T L E V E L A D P A G S A G R V G P T S A G S G G G G R R R R A R R P K R T I L I D C E K R I T S C K G T Q A D V V L F F I H G V G G S L A I W K E Q L D F F V R L G Y E V V A P D L A G H G A S S A P Q V A A A Y T F Y A L A E D M R A I F K R Y A K K R N V L I G H S Y G V S F C T F L A H E Y P D L V H K V I M I N G G G P T A L E P S F C S I F N M P T C V L H C L S P C L A W S F L K A G F A R Q G A K E K Q L L K E G N A F N V S S F V L R A M M S G Q Y W P E G D E V Y H A E L T V P V L L V H G M H D K F V P V E E D Q R M A E I L L L A F L K L I D E G S H M V M L E C P E T V N T L L H E F L L W E P E P A P K A L P A P P E E K
Reference
Title: Genome sequence, comparative analysis, and population genetics of the domestic horseWade CM , Giulotto E , Sigurdsson S , Zoli M , Gnerre S , Imsland F , Lear TL , Adelson DL , Bailey E and Lindblad-Toh K <48 more author(s)> Wade CM , Giulotto E , Sigurdsson S , Zoli M , Gnerre S , Imsland F , Lear TL , Adelson DL , Bailey E , Bellone RR , Blocker H , Distl O , Edgar RC , Garber M , Leeb T , Mauceli E , MacLeod JN , Penedo MC , Raison JM , Sharpe T , Vogel J , Andersson L , Antczak DF , Biagi T , Binns MM , Chowdhary BP , Coleman SJ , Della Valle G , Fryc S , Guerin G , Hasegawa T , Hill EW , Jurka J , Kiialainen A , Lindgren G , Liu J , Magnani E , Mickelson JR , Murray J , Nergadze SG , Onofrio R , Pedroni S , Piras MF , Raudsepp T , Rocchi M , Roed KH , Ryder OA , Searle S , Skow L , Swinburne JE , Syvanen AC , Tozaki T , Valberg SJ , Vaudin M , White JR , Zody MC , Lander ES , Lindblad-Toh K (- 48) Ref: Science, 326 :865, 2009 : PubMed Abstract ESTHER: Wade_2009_Science_326_865 PubMedSearch: Wade 2009 Science 326 865 PubMedID: 19892987 Gene_locus related to this paper: horse-1plip ,
horse-2plrp ,
horse-ACHE ,
horse-BCHE ,
horse-f6pri5 ,
horse-f6qlk6 ,
horse-f6qsc5 ,
horse-f6r958 ,
horse-f6sfg0 ,
horse-f6uif6 ,
horse-f6un85 ,
horse-f6vxp7 ,
horse-f6wfs9 ,
horse-f6wzv8 ,
horse-f6x0i7 ,
horse-f6x5e5 ,
horse-f6zmg7 ,
horse-f7afw6 ,
horse-f7agv7 ,
horse-f7bj10 ,
horse-f7bk45 ,
horse-f7bvl6 ,
horse-f7c7a8 ,
horse-f7cdt1 ,
horse-f7cxj0 ,
horse-f6ut17 ,
horse-f6svq9 ,
horse-f6xgj6 ,
horse-f6s101 ,
horse-f6wfa7 ,
horse-f7cpx3 ,
horse-f7adj7 ,
horse-f6r609 ,
horse-f6y0j2 ,
horse-f6zvb2 ,
horse-f7e4g0 ,
horse-f6ti02 ,
horse-f6re01 ,
horse-f6xmp6 ,
horse-f6vts1 ,
horse-f6quf7 ,
horse-f6tn81 ,
horse-f7bm46 ,
horse-f6q1u3 ,
horse-f6zna7 ,
horse-f6q208 ,
horse-f7cuh0 ,
horse-f6tq73 ,
horse-f6xa70 ,
horse-f6qj19 ,
horse-f6wgf3 ,
horse-f7d8t6 ,
horse-f6ul42 ,
horse-f7am73 ,
horse-f7dme2 Abstract
We report a high-quality draft sequence of the genome of the horse (Equus caballus). The genome is relatively repetitive but has little segmental duplication. Chromosomes appear to have undergone few historical rearrangements: 53% of equine chromosomes show conserved synteny to a single human chromosome. Equine chromosome 11 is shown to have an evolutionary new centromere devoid of centromeric satellite DNA, suggesting that centromeric function may arise before satellite repeat accumulation. Linkage disequilibrium, showing the influences of early domestication of large herds of female horses, is intermediate in length between dog and human, and there is long-range haplotype sharing among breeds.
Other Papers
Equus caballus, Horse mRNA for triacylglycerol lipase