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Gene_locus Report for: fashe-a0a4e0rjz9

Fasciola hepatica (Liver fluke) Neurotactin

Relationship
Family|Neurotactin
Block| C
Position in NCBI Life Tree|Fasciola hepatica
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Platyhelminthes: N E > Trematoda: N E > Digenea: N E > Plagiorchiida: N E > Echinostomata: N E > Echinostomatoidea: N E > Fasciolidae: N E > Fasciola: N E > Fasciola hepatica: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : THD28606
1 UniProt : A0A4E0RJZ9
1 UniProt : A0A4E0RJZ9
1 Interpro : A0A4E0RJZ9
1 Pfam : A0A4E0RJZ9
1 PIRSF : A0A4E0RJZ9
1 SUPERFAM : A0A4E0RJZ9
Sequence
Graphical view for this peptide sequence: fashe-a0a4e0rjz9
Colored MSA for Neurotactin (raw)
MSGETIVNITFKTIKPPESFFDIGRPLVDPHRPRLYLQRRFDFLLLLGIA
LSFVALVAHLFLVVIQLPEVPPATSYVISQCASMDGEWNQEKNVLRYWAV
PYAVPPVIEADTSFPEVMHDIAEKYSIPRGGFRWHRTFTVPDTEYCFLSF
DDRCEFVDGRWNCRMRHLNRTAACVELDEAGEIIGNATEHCLTLDISMPV
FKGTLLPVIVVFTGFRSLRSPMSGSKRNEPAYLPTDEAVLRFGAIWINAR
YRLGPFGSFYDFSRIGLTEKETHYMNFALRDQLAVLTWVQHNVGRFGGDA
SKVVLLAHGSGATSALALVQLQSRLNFSVPWFRSVWIASGALNWYDEKRA
SWQELIPYKIFTSLASCPWGLQKKVLHSNSPCAVTLRDKFMKMDLHTLTG
IFKKQYEDWSAGILSTNRLQDTKPSMWYAIDQEFNLSAPPEWSRETVDRM
FIHVNNYTRPNLHTLVFSSMSSEFEGFPGTADESQSDISSFKELLNQVVF
PQYKGLFERLIHFEDIRARKPAAWPARMKDWDLMLSALSAVRYACPQAWL
IANWLINRTLHEEVGRTKFYHIIHQEAPRYSYSNIPAPPNSGNRRLPFHG
LDMLILTGNYQNQPISFDSYRYHLWENFNNFVQGQPLSNLCEITPNPEAD
EPVAEVGCLMTSYGAHKAQLNFTVDSICRQIDWESHYYDLAMYE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MSGETIVNITFKTIKPPESFFDIGRPLVDPHRPRLYLQRRFDFLLLLGIA
LSFVALVAHLFLVVIQLPEVPPATSYVISQCASMDGEWNQEKNVLRYWAV
PYAVPPVIEADTSFPEVMHDIAEKYSIPRGGFRWHRTFTVPDTEYCFLSF
DDRCEFVDGRWNCRMRHLNRTAACVELDEAGEIIGNATEHCLTLDISMPV
FKGTLLPVIVVFTGFRSLRSPMSGSKRNEPAYLPTDEAVLRFGAIWINAR
YRLGPFGSFYDFSRIGLTEKETHYMNFALRDQLAVLTWVQHNVGRFGGDA
SKVVLLAHGSGATSALALVQLQSRLNFSVPWFRSVWIASGALNWYDEKRA
SWQELIPYKIFTSLASCPWGLQKKVLHSNSPCAVTLRDKFMKMDLHTLTG
IFKKQYEDWSAGILSTNRLQDTKPSMWYAIDQEFNLSAPPEWSRETVDRM
FIHVNNYTRPNLHTLVFSSMSSEFEGFPGTADESQSDISSFKELLNQVVF
PQYKGLFERLIHFEDIRARKPAAWPARMKDWDLMLSALSAVRYACPQAWL
IANWLINRTLHEEVGRTKFYHIIHQEAPRYSYSNIPAPPNSGNRRLPFHG
LDMLILTGNYQNQPISFDSYRYHLWENFNNFVQGQPLSNLCEITPNPEAD
EPVAEVGCLMTSYGAHKAQLNFTVDSICRQIDWESHYYDLAMYE


Reference
    Title: Transcriptome-Based Identification of a Functional Fasciola hepatica Carboxylesterase B
    Pedroza-Gomez YJ, Cossio-Bayugar R, Aguilar-Diaz H, Scarcella S, Reynaud E, Sanchez-Carbente MDR, Narvaez-Padilla V, Miranda-Miranda E
    Ref: Pathogens, 10:1454, 2021 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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