Gene_locus Report for: emeni-q5ax97 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans). DltD N-terminal domain protein (AFU_orthologue AFUA_8G00380)
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Fungi: N E > Dikarya: N E > Ascomycota: N E > saccharomyceta: N E > Pezizomycotina: N E > leotiomyceta: N E > Eurotiomycetes: N E > Eurotiomycetidae: N E > Eurotiales: N E > Aspergillaceae: N E > Aspergillus: N E > Aspergillus nidulans: N E 6_AlphaBeta_hydrolase :
emeni-q5ax50 Emericella nidulans (Aspergillus nidulans) Aspergillus nidulans FGSC A4 Putative uncharacterized protein ,
emeni-q5b5j7 Emericella nidulans (Aspergillus nidulans) Putative uncharacterized protein ,
emeni-q5b938 Emericella nidulans (Aspergillus nidulans) Aspergillus nidulans FGSC A4 Putative uncharacterized protein ,
emeni-q5ba78 Emericella nidulans (Aspergillus nidulans) Aspergillus nidulans FGSC A4 Putative uncharacterized protein .
A85-IroE-IroD-Fes-Yiel :
emeni-AnEstB ,
emeni-q5av79 .
ABHD11-Acetyl_transferase :
emeni-c8vu15 Emericella nidulans (Aspergillus nidulans). Alpha/beta hydrolase, putative (AFU_orthologue AFUA_1G02390) .
Acidic_Lipase :
emeni-q5b446 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR 194 / M139) (Aspergillus nidulans) Triglyceride lipase-cholesterol esterase, putative (AFU_orthologue; AFUA_5G08960) ,
emeni-q5bcd2 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR 194 / M139) (Aspergillus nidulans) Ab-hydrolase associated lipase, putative (AFU_orthologue; AFUA_2G14600) .
Arb2_domain :
emend-q7z8l7 Emericella nidulans (Aspergillus nidulans). Putative histone deacetylase Arb2 domain .
BD-FAE :
emeni-q5az32 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR 194 / M139) (Aspergillus nidulans) Polyketide synthase, putative (JCVI) .
Carboxypeptidase_S10 :
emeni-CBPYA Emericella nidulans (Aspergillus nidulans) carboxypeptidase .
Duf_726 :
emeni-q5azl2 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) Putative uncharacterized protein ,
emeni-q5b602 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) Putative uncharacterized protein .
Duf_829 :
emeni-q5b1v2 Emericella nidulans (Aspergillus nidulans) Putative uncharacterized protein ,
emeni-q5bar0 Emericella nidulans (Aspergillus nidulans) Putative uncharacterized protein ,
emeni-q5beh9 Emericella nidulans (Aspergillus nidulans) Putative uncharacterized protein ,
emeni-q5bgk7 Emericella nidulans (Aspergillus nidulans) Putative uncharacterized protein .
Duf_1100-S :
emeni-q5ara9 Aspergillus nidulans FGSC A4 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR 194 / M139) (Aspergillus nidulans) hypothetical protein .
Esterase_phb :
emeni-axe1 Emericella nidulans (Aspergillus nidulans) AN6093-2 Acetylxylan esterase A .
FaeC :
emeni-faec Emericella nidulans (Aspergillus nidulans) AN5267.2 Ferulic acid esterase C .
FSH1 :
emeni-afoc Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans). Asperfuranone biosynthesis protein B ,
emeni-dbae Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans). Derivative of benzaldehyde biosynthesis cluster protein E .
Fungal-Bact_LIP :
emeni-q5ay57 Aspergillus nidulans FGSC A4 hypothetical protein ,
emeni-q5bcd1 Aspergillus nidulans, Emericella nidulans, hypothetical protein .
Fusarinine_C_esterase_sidJ :
emeni-q5ay37 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR 194 / M139) (Aspergillus nidulans) Esterase, putative (AFU_orthologue; AFUA_7G00330) .
Homoserine_transacetylase :
emeni-CYSC Emericella nidulans (Aspergillus nidulans) putative homoserine o-acetyltransferase ,
emeni-met2 Emericella nidulans (Aspergillus nidulans) .
Hormone-sensitive_lipase_like :
emeni-stci Emericella nidulans (and Aspergillus nidulans FGSC A4) stcI gene in sterigmatocystin biosynthetic cluster .
Kynurenine-formamidase :
emeni-q5bdv9 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans). N-formylkynurenine formamidase .
LIDHydrolase :
emeni-q5avd3 Emericella nidulans (Aspergillus nidulans) Putative uncharacterized protein .
Lipase_3 :
emeni-atg15 Emericella nidulans (Aspergillus nidulans) putative lipase atg15 (EC 3.1.1.3) (autophagy-related protein 15) .
MpaH :
emeni-q5b719 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans). Toxin biosynthesis protein, putative (AFU_orthologue AFUA_4G12320) .
Prolylcarboxypeptidase :
emeni-q5awu9 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR 194 / M139) (Aspergillus nidulans) Hypothetical serine carboxypeptidase (Eurofung) .
Thioesterase :
emeni-acvs Emericella nidulans (Aspergillus nidulans) Aspergillus nidulans FGSC A4 acv synthetase (acvs) Thioesterase domain ,
emeni-q4j6a7 Emericella nidulans (Aspergillus nidulans) acv synthetase (fragment) ,
emeni-stca Emericella nidulans (Aspergillus nidulans) Aspergillus nidulans FGSC A4 putative sterigmatocystin biosynthesis polyketide synthase (pks)Thioesterase domain Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: emeni-q5ax97 Colored MSA for Thiohydrolase (raw)
MLGLPDVALHFQTAGVTVLLYDPRSTGLSDGTPRNEIDPVKQAADYSDAL
TFLSTQASVYPSQLFFWGMSFSAVVALCAATTDKRIRGVLAIAPLTDLTY
KPEHRRAKVLQQCMQDRASQSAGNEPYYLPLLNEQGENPAGFGVGLEREE
YARIVAAGRKLAKGHVNRTTIQSYYHMAMWQPFGLWAGVAPTPVMFVVPE
MDTVSPAERQREYFDTKLGNAPRRLHLVEGAGHMDIVQGAHLEGLMEVKM
RFVQDILEGRVEVSGDETR
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M L G L P D V A L H F Q T A G V T V L L Y D P R S T G L S D G T P R N E I D P V K Q A A D Y S D A L T F L S T Q A S V Y P S Q L F F W G M S F S A V V A L C A A T T D K R I R G V L A I A P L T D L T Y K P E H R R A K V L Q Q C M Q D R A S Q S A G N E P Y Y L P L L N E Q G E N P A G F G V G L E R E E Y A R I V A A G R K L A K G H V N R T T I Q S Y Y H M A M W Q P F G L W A G V A P T P V M F V V P E M D T V S P A E R Q R E Y F D T K L G N A P R R L H L V E G A G H M D I V Q G A H L E G L M E V K M R F V Q D I L E G R V E V S G D E T R
References
Title: The 2008 update of the Aspergillus nidulans genome annotation: a community effortWortman JR , Gilsenan JM , Joardar V , Deegan J , Clutterbuck J , Andersen MR , Archer D , Bencina M , Braus G and Turner G <76 more author(s)> Wortman JR , Gilsenan JM , Joardar V , Deegan J , Clutterbuck J , Andersen MR , Archer D , Bencina M , Braus G , Coutinho P , von Dohren H , Doonan J , Driessen AJ , Durek P , Espeso E , Fekete E , Flipphi M , Estrada CG , Geysens S , Goldman G , de Groot PW , Hansen K , Harris SD , Heinekamp T , Helmstaedt K , Henrissat B , Hofmann G , Homan T , Horio T , Horiuchi H , James S , Jones M , Karaffa L , Karanyi Z , Kato M , Keller N , Kelly DE , Kiel JA , Kim JM , van der Klei IJ , Klis FM , Kovalchuk A , Krasevec N , Kubicek CP , Liu B , Maccabe A , Meyer V , Mirabito P , Miskei M , Mos M , Mullins J , Nelson DR , Nielsen J , Oakley BR , Osmani SA , Pakula T , Paszewski A , Paulsen I , Pilsyk S , Pocsi I , Punt PJ , Ram AF , Ren Q , Robellet X , Robson G , Seiboth B , van Solingen P , Specht T , Sun J , Taheri-Talesh N , Takeshita N , Ussery D , vanKuyk PA , Visser H , van de Vondervoort PJ , de Vries RP , Walton J , Xiang X , Xiong Y , Zeng AP , Brandt BW , Cornell MJ , van den Hondel CA , Visser J , Oliver SG , Turner G (- 76) Ref: Fungal Genet Biol, 46 Suppl 1 :S2, 2009 : PubMed Abstract ESTHER: Wortman_2009_Fungal.Genet.Biol_46 Suppl 1_S2 PubMedSearch: Wortman 2009 Fungal.Genet.Biol 46 Suppl 1 S2 PubMedID: 19146970 Gene_locus related to this paper: emeni-axe1 ,
emeni-c8v4m7 ,
emeni-faec ,
emeni-ppme1 ,
emeni-q5ara9 ,
emeni-q5arf0 ,
emeni-q5as30 ,
emeni-q5ase8 ,
emeni-q5av79 ,
emeni-q5aw09 ,
emeni-q5awc3 ,
emeni-q5awc7 ,
emeni-q5awu9 ,
emeni-q5aww4 ,
emeni-q5ax50 ,
emeni-q5ay37 ,
emeni-q5ay57 ,
emeni-q5ay59 ,
emeni-q5ayk9 ,
emeni-q5ays5 ,
emeni-q5az32 ,
emeni-q5az91 ,
emeni-q5az97 ,
emeni-q5azp1 ,
emeni-q5b0i6 ,
emeni-q5b1h2 ,
emeni-q5b2a9 ,
emeni-q5b2p7 ,
emeni-q5b3d2 ,
emeni-q5b4q7 ,
emeni-q5b5u7 ,
emeni-q5b5y4 ,
emeni-q5b9e7 ,
emeni-q5b9i0 ,
emeni-q5b364 ,
emeni-q5b446 ,
emeni-q5b938 ,
emeni-q5ba78 ,
emeni-q5bcd1 ,
emeni-q5bcd2 ,
emeni-q5bde7 ,
emeni-q5bdr0 ,
emeni-q5bf92 ,
emeni-q7si80 ,
emeni-q5bdv9 ,
emeni-c8vu15 ,
9euro-a0a3d8t644 ,
emeni-q5b719 ,
emeni-q5ax97 ,
emeni-tdia ,
emeni-afoc ,
emeni-dbae Abstract
The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.
Title: Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzaeGalagan JE , Calvo SE , Cuomo C , Ma LJ , Wortman JR , Batzoglou S , Lee SI , Basturkmen M , Spevak CC and Birren BW <40 more author(s)> Galagan JE , Calvo SE , Cuomo C , Ma LJ , Wortman JR , Batzoglou S , Lee SI , Basturkmen M , Spevak CC , Clutterbuck J , Kapitonov V , Jurka J , Scazzocchio C , Farman M , Butler J , Purcell S , Harris S , Braus GH , Draht O , Busch S , d'Enfert C , Bouchier C , Goldman GH , Bell-Pedersen D , Griffiths-Jones S , Doonan JH , Yu J , Vienken K , Pain A , Freitag M , Selker EU , Archer DB , Penalva MA , Oakley BR , Momany M , Tanaka T , Kumagai T , Asai K , Machida M , Nierman WC , Denning DW , Caddick M , Hynes M , Paoletti M , Fischer R , Miller B , Dyer P , Sachs MS , Osmani SA , Birren BW (- 40) Ref: Nature, 438 :1105, 2005 : PubMed Abstract ESTHER: Galagan_2005_Nature_438_1105 PubMedSearch: Galagan 2005 Nature 438 1105 PubMedID: 16372000 Gene_locus related to this paper: emeni-axe1 ,
emeni-BST1 ,
emeni-c8vrl3 ,
emeni-CUTI3 ,
emeni-faec ,
emeni-ppme1 ,
emeni-q5aqv0 ,
emeni-q5ara9 ,
emeni-q5av79 ,
emeni-q5avd3 ,
emeni-q5awc7 ,
emeni-q5awq3 ,
emeni-q5awu9 ,
emeni-q5aww7 ,
emeni-q5ax50 ,
emeni-q5ay37 ,
emeni-q5ay57 ,
emeni-q5ayk9 ,
emeni-q5az32 ,
emeni-q5azl2 ,
emeni-q5azp1 ,
emeni-q5b1v2 ,
emeni-q5b2c1 ,
emeni-q5b3d2 ,
emeni-q5b5j7 ,
emeni-q5b7i6 ,
emeni-q5b8p6 ,
emeni-q5b9e7 ,
emeni-q5b246 ,
emeni-q5b446 ,
emeni-q5b602 ,
emeni-q5b938 ,
emeni-q5ba78 ,
emeni-q5bad3 ,
emeni-q5bar0 ,
emeni-q5bcd1 ,
emeni-q5bcd2 ,
emeni-q5bcf8 ,
emeni-q5bdr0 ,
emeni-q5beh9 ,
emeni-q5bgk7 ,
emeni-q7si80 ,
emeni-q5bdv9 ,
emeni-c8vu15 ,
9euro-a0a3d8t644 ,
emeni-q5b719 ,
emeni-q5ax97 ,
emeni-tdia ,
emeni-afoc ,
emeni-dbae Abstract
The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million years of evolution. Here we report the genome sequence of the model organism Aspergillus nidulans, and a comparative study with Aspergillus fumigatus, a serious human pathogen, and Aspergillus oryzae, used in the production of sake, miso and soy sauce. Our analysis of genome structure provided a quantitative evaluation of forces driving long-term eukaryotic genome evolution. It also led to an experimentally validated model of mating-type locus evolution, suggesting the potential for sexual reproduction in A. fumigatus and A. oryzae. Our analysis of sequence conservation revealed over 5,000 non-coding regions actively conserved across all three species. Within these regions, we identified potential functional elements including a previously uncharacterized TPP riboswitch and motifs suggesting regulation in filamentous fungi by Puf family genes. We further obtained comparative and experimental evidence indicating widespread translational regulation by upstream open reading frames. These results enhance our understanding of these widely studied fungi as well as provide new insight into eukaryotic genome evolution and gene regulation.
Other Papers
Emericella nidulans (Aspergillus nidulans) siderophore-degrading esterase AnEstB