Gene_locus Report for: droya-q71d76 Drosophila yakuba (Fruit fly) 1(2)k09913 Drosophila erecta L(2)k09913-PA (Lethal (2) k09913)
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > melanogaster group: N E > melanogaster subgroup: N E > Drosophila yakuba: N E A85-EsteraseD-FGH :
droya-b4pp65 Drosophila yakuba (Fruit fly) GE25088 .
ABHD18 :
droya-b4pgu0 Drosophila yakuba (Fruit fly) GE21919 .
abh_upf0017 :
droya-b4nxe6 Drosophila yakuba (Fruit fly) GE18216 ,
droya-b4p3x8 Drosophila yakuba (Fruit fly) GE19258 .
ACHE :
droya-ACHE Drosophila yakuba (Fruit fly); Drosophila ficusphila acetylcholinesterase GE24460 .
Acidic_Lipase :
droya-b4nxw4 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0q9 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0r0 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0r7 Drosophila yakuba (Fruit fly) GE13495 ,
droya-b4p0r8 Drosophila yakuba (Fruit fly) GE18474 ,
droya-b4p0r9 Drosophila yakuba (Fruit fly) GE18475 ,
droya-b4p0s0 Drosophila yakuba (Fruit fly) GE18476 ,
droya-b4p0s2 Drosophila yakuba (Fruit fly) GE18478 ,
droya-b4p0t0 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0t1 Drosophila yakuba (Fruit fly) GE13417 ,
droya-b4p6c9 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p7u4 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4pet9 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc5 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc6 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc7 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc8 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4pq03 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4psz8 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4psz9 Drosophila yakuba (Fruit fly) Lipase .
Carb_B_Arthropoda :
droya-aes04 Drosophila yakuba (Fruit fly)alpha-esterase 4a (aE4a) gene, partial cds ,
droya-b4iuv4 Drosophila yakuba (Fruit fly) DyakGE11183 ,
droya-b4iuv5 Drosophila yakuba (Fruit fly) GE11113 ,
droya-b4ny57 Drosophila yakuba (Fruit fly) GE18855 ,
droya-b4p5g8 Drosophila yakuba (Fruit fly) GE13995 ,
droya-b4p8w7 Drosophila yakuba (Fruit fly) GE13694 ,
droya-b4pdm8 Drosophila yakuba (Fruit fly) GE19762 ,
droya-b4pga7 Drosophila yakuba (Fruit fly) Est-7 ,
droya-b4plh2 Drosophila yakuba (Fruit fly) GE26073 ,
droya-b4pn92 Drosophila yakuba (Fruit fly) GE23951 ,
droya-b4prg6B Drosophila yakuba (Fruit fly) GE25781 ,
droya-b4prg9 Drosophila yakuba (Fruit fly) GE25783 ,
droya-b4prh3 Drosophila yakuba (Fruit fly) GE24932 ,
droya-b4prh4 Drosophila yakuba (Fruit fly) GE25786 ,
droya-b4prh6 Drosophila yakuba (Fruit fly) GE25790 GE14824 ,
droya-b4prh7 Drosophila yakuba (Fruit fly) GE25791 ,
droya-b4q0g5 Drosophila yakuba (Fruit fly) GE16876 ,
droya-EST6 Drosophila yakuba (Fruit fly) (and Drosophila santomea) b-carboxyl esterase (EC 3.1.1.1) .
CGI-58_ABHD5_ABHD4 :
droya-b4p241 Drosophila yakuba (Fruit fly) GE19151 .
DPP4N_Peptidase_S9 :
droya-b4p0b5 Drosophila yakuba (Fruit fly) GE18428 ,
droya-b4p023 Drosophila yakuba (Fruit fly) GE25657 ,
droya-b4pig3 Drosophila yakuba (Fruit fly) GE22026 ,
droya-b4pv22 Drosophila yakuba (Fruit fly) GE10760 ,
droya-b4q246 Drosophila yakuba (Fruit fly) GE15628 .
Gliotactin :
droya-b4ny86 Drosophila yakuba (Fruit fly) GE19390 .
Glutactin :
droya-b4nxg5 Drosophila yakuba (Fruit fly) GE18789 ,
droya-b4nxg6 Drosophila yakuba (Fruit fly) GE10861 ,
droya-b4nxg8 Drosophila yakuba (Fruit fly) GE10839 .
Juvenile_hormone_esterase :
droya-b4p6r1 Drosophila yakuba (Fruit fly) GE11755 ,
droya-b4p6r2 Drosophila yakuba (Fruit fly) GE11753 .
LIDHydrolase :
droya-b4pd70 Drosophila yakuba (Fruit fly) GE20970 .
Neuroligin :
droya-b4nzz8 Drosophila yakuba (Fruit fly) GE14187 .
Neurotactin :
droya-b4pka2 Drosophila yakuba (Fruit fly) GE19873 .
NLS3-Tex30 :
droya-b4p6l9 Drosophila yakuba (Fruit fly) GE12338 .
OtherNon-catalytic_C :
droya-b4ny58 Drosophila yakuba (Fruit fly) GE10446 ,
droya-b4p3h4 Drosophila yakuba (Fruit fly) GE17517 ,
droya-b4p774 Drosophila yakuba (Fruit fly) GE13597 ,
droya-b4pat9 Drosophila yakuba (Fruit fly) GE11486 .
Pectinacetylesterase-Notum :
droya-b4itu9 Drosophila yakuba (Fruit fly) GE22884 ,
droya-b4pd22 Drosophila yakuba (Fruit fly) GE19800 .
PPase_methylesterase_euk :
droya-b4pff9 Drosophila yakuba (Fruit fly) Protein phosphatase methylesterase 1 .
Prolylcarboxypeptidase :
droya-b4pbl1 Drosophila yakuba (Fruit fly) GE12590 ,
droya-b4pjt8 Drosophila yakuba (Fruit fly) GE21585 ,
droya-b4pmv3 Drosophila yakuba (Fruit fly) GE25599 ,
droya-b4pmv4 Drosophila yakuba (Fruit fly) GE25600 ,
droya-b4pmv5 Drosophila yakuba (Fruit fly) GE25604 .
SERHL :
droya-b4itg2 Drosophila yakuba (Fruit fly) GE23049 ,
droya-b4itg6 Drosophila yakuba (Fruit fly); Drosophila ficusphila (Fruit fly) GE22964 ,
droya-b4p2y4 Drosophila yakuba (Fruit fly). Uncharacterized protein .
Valacyclovir-hydrolase :
droya-b4pma3 Drosophila yakuba (Fruit fly) GE24034 Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can
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(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Drosophila erecta:
N ,
E .
Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: droya-q71d76 Colored MSA for Duf_829 (raw)
MAAHFFRTAFYATAARKSMSLPFAGRTAATLAVGLSFGAQNSRAAVPYEN
AYADSFFGGCQTQGLLQRVPHTGHIQPPLIRNFSSLQTGHQQQQPAPNSA
MAPSNNRRYLSSQDITKNMTLYTSTKTQVEVDPKTLAFKKPTGNPLCLMM
AWLMAKQKHLKKYAQIYTEMGFDVVVVHITPWQLLWPVKGTQVVAAETIR
FLENNKSYEPIVMHGFSVGAYQLGEIMLQMSRDMDRYGSILDRFVCQIWD
SAADITEIPIGVPKSIFPRNERMQSALRNYTLYHMKTFHNQATIHYMRSS
QMFHSTLVKAPALFFVSDNDPIGPPSSNHAVREDWERANIKVTFKCWERS
QHAAHYIRHREEYLQTLFQHLEACGVLEAIGVPKRAKL
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M A A H F F R T A F Y A T A A R K S M S L P F A G R T A A T L A V G L S F G A Q N S R A A V P Y E N A Y A D S F F G G C Q T Q G L L Q R V P H T G H I Q P P L I R N F S S L Q T G H Q Q Q Q P A P N S A M A P S N N R R Y L S S Q D I T K N M T L Y T S T K T Q V E V D P K T L A F K K P T G N P L C L M M A W L M A K Q K H L K K Y A Q I Y T E M G F D V V V V H I T P W Q L L W P V K G T Q V V A A E T I R F L E N N K S Y E P I V M H G F S V G A Y Q L G E I M L Q M S R D M D R Y G S I L D R F V C Q I W D S A A D I T E I P I G V P K S I F P R N E R M Q S A L R N Y T L Y H M K T F H N Q A T I H Y M R S S Q M F H S T L V K A P A L F F V S D N D P I G P P S S N H A V R E D W E R A N I K V T F K C W E R S Q H A A H Y I R H R E E Y L Q T L F Q H L E A C G V L E A I G V P K R A K L
References
1 more
Title: Evolution of genes and genomes on the Drosophila phylogenyClark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W and MacCallum I <405 more author(s)> Clark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W , Iyer VN , Pollard DA , Sackton TB , Larracuente AM , Singh ND , Abad JP , Abt DN , Adryan B , Aguade M , Akashi H , Anderson WW , Aquadro CF , Ardell DH , Arguello R , Artieri CG , Barbash DA , Barker D , Barsanti P , Batterham P , Batzoglou S , Begun D , Bhutkar A , Blanco E , Bosak SA , Bradley RK , Brand AD , Brent MR , Brooks AN , Brown RH , Butlin RK , Caggese C , Calvi BR , Bernardo de Carvalho A , Caspi A , Castrezana S , Celniker SE , Chang JL , Chapple C , Chatterji S , Chinwalla A , Civetta A , Clifton SW , Comeron JM , Costello JC , Coyne JA , Daub J , David RG , Delcher AL , Delehaunty K , Do CB , Ebling H , Edwards K , Eickbush T , Evans JD , Filipski A , Findeiss S , Freyhult E , Fulton L , Fulton R , Garcia AC , Gardiner A , Garfield DA , Garvin BE , Gibson G , Gilbert D , Gnerre S , Godfrey J , Good R , Gotea V , Gravely B , Greenberg AJ , Griffiths-Jones S , Gross S , Guigo R , Gustafson EA , Haerty W , Hahn MW , Halligan DL , Halpern AL , Halter GM , Han MV , Heger A , Hillier L , Hinrichs AS , Holmes I , Hoskins RA , Hubisz MJ , Hultmark D , Huntley MA , Jaffe DB , Jagadeeshan S , Jeck WR , Johnson J , Jones CD , Jordan WC , Karpen GH , Kataoka E , Keightley PD , Kheradpour P , Kirkness EF , Koerich LB , Kristiansen K , Kudrna D , Kulathinal RJ , Kumar S , Kwok R , Lander E , Langley CH , Lapoint R , Lazzaro BP , Lee SJ , Levesque L , Li R , Lin CF , Lin MF , Lindblad-Toh K , Llopart A , Long M , Low L , Lozovsky E , Lu J , Luo M , Machado CA , Makalowski W , Marzo M , Matsuda M , Matzkin L , McAllister B , McBride CS , McKernan B , McKernan K , Mendez-Lago M , Minx P , Mollenhauer MU , Montooth K , Mount SM , Mu X , Myers E , Negre B , Newfeld S , Nielsen R , Noor MA , O'Grady P , Pachter L , Papaceit M , Parisi MJ , Parisi M , Parts L , Pedersen JS , Pesole G , Phillippy AM , Ponting CP , Pop M , Porcelli D , Powell JR , Prohaska S , Pruitt K , Puig M , Quesneville H , Ram KR , Rand D , Rasmussen MD , Reed LK , Reenan R , Reily A , Remington KA , Rieger TT , Ritchie MG , Robin C , Rogers YH , Rohde C , Rozas J , Rubenfield MJ , Ruiz A , Russo S , Salzberg SL , Sanchez-Gracia A , Saranga DJ , Sato H , Schaeffer SW , Schatz MC , Schlenke T , Schwartz R , Segarra C , Singh RS , Sirot L , Sirota M , Sisneros NB , Smith CD , Smith TF , Spieth J , Stage DE , Stark A , Stephan W , Strausberg RL , Strempel S , Sturgill D , Sutton G , Sutton GG , Tao W , Teichmann S , Tobari YN , Tomimura Y , Tsolas JM , Valente VL , Venter E , Venter JC , Vicario S , Vieira FG , Vilella AJ , Villasante A , Walenz B , Wang J , Wasserman M , Watts T , Wilson D , Wilson RK , Wing RA , Wolfner MF , Wong A , Wong GK , Wu CI , Wu G , Yamamoto D , Yang HP , Yang SP , Yorke JA , Yoshida K , Zdobnov E , Zhang P , Zhang Y , Zimin AV , Baldwin J , Abdouelleil A , Abdulkadir J , Abebe A , Abera B , Abreu J , Acer SC , Aftuck L , Alexander A , An P , Anderson E , Anderson S , Arachi H , Azer M , Bachantsang P , Barry A , Bayul T , Berlin A , Bessette D , Bloom T , Blye J , Boguslavskiy L , Bonnet C , Boukhgalter B , Bourzgui I , Brown A , Cahill P , Channer S , Cheshatsang Y , Chuda L , Citroen M , Collymore A , Cooke P , Costello M , D'Aco K , Daza R , De Haan G , DeGray S , DeMaso C , Dhargay N , Dooley K , Dooley E , Doricent M , Dorje P , Dorjee K , Dupes A , Elong R , Falk J , Farina A , Faro S , Ferguson D , Fisher S , Foley CD , Franke A , Friedrich D , Gadbois L , Gearin G , Gearin CR , Giannoukos G , Goode T , Graham J , Grandbois E , Grewal S , Gyaltsen K , Hafez N , Hagos B , Hall J , Henson C , Hollinger A , Honan T , Huard MD , Hughes L , Hurhula B , Husby ME , Kamat A , Kanga B , Kashin S , Khazanovich D , Kisner P , Lance K , Lara M , Lee W , Lennon N , Letendre F , LeVine R , Lipovsky A , Liu X , Liu J , Liu S , Lokyitsang T , Lokyitsang Y , Lubonja R , Lui A , Macdonald P , Magnisalis V , Maru K , Matthews C , McCusker W , McDonough S , Mehta T , Meldrim J , Meneus L , Mihai O , Mihalev A , Mihova T , Mittelman R , Mlenga V , Montmayeur A , Mulrain L , Navidi A , Naylor J , Negash T , Nguyen T , Nguyen N , Nicol R , Norbu C , Norbu N , Novod N , O'Neill B , Osman S , Markiewicz E , Oyono OL , Patti C , Phunkhang P , Pierre F , Priest M , Raghuraman S , Rege F , Reyes R , Rise C , Rogov P , Ross K , Ryan E , Settipalli S , Shea T , Sherpa N , Shi L , Shih D , Sparrow T , Spaulding J , Stalker J , Stange-Thomann N , Stavropoulos S , Stone C , Strader C , Tesfaye S , Thomson T , Thoulutsang Y , Thoulutsang D , Topham K , Topping I , Tsamla T , Vassiliev H , Vo A , Wangchuk T , Wangdi T , Weiand M , Wilkinson J , Wilson A , Yadav S , Young G , Yu Q , Zembek L , Zhong D , Zimmer A , Zwirko Z , Alvarez P , Brockman W , Butler J , Chin C , Grabherr M , Kleber M , Mauceli E , MacCallum I (- 405) Ref: Nature, 450 :203, 2007 : PubMed Abstract ESTHER: Clark_2007_Nature_450_203 PubMedSearch: Clark 2007 Nature 450 203 PubMedID: 17994087 Gene_locus related to this paper: droan-ACHE ,
droan-b3lx10 ,
droan-b3lx75 ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
droan-b3lyh7 ,
droan-b3lyh9 ,
droan-b3lyi0 ,
droan-b3lyi2 ,
droan-b3lyi3 ,
droan-b3lyi4 ,
droan-b3lyj8 ,
droan-b3lyj9 ,
droan-b3lyx4 ,
droan-b3lyx5 ,
droan-b3lyx6 ,
droan-b3lyx7 ,
droan-b3lyx9 ,
droan-b3lz72 ,
droan-b3m1x3 ,
droan-b3m2d4 ,
droan-b3m3d9 ,
droan-b3m4e3 ,
droan-b3m5w1 ,
droan-b3m6i7 ,
droan-b3m7v2 ,
droan-b3m9a5 ,
droan-b3m9f4 ,
droan-b3m9p3 ,
droan-b3m254 ,
droan-b3m259 ,
droan-b3m260 ,
droan-b3m262 ,
droan-b3m524 ,
droan-b3m635 ,
droan-b3m845 ,
droan-b3m846 ,
droan-b3md01 ,
droan-b3mdh7 ,
droan-b3mdm6 ,
droan-b3mdw8 ,
droan-b3mee1 ,
droan-b3mf47 ,
droan-b3mf48 ,
droan-b3mg94 ,
droan-b3mgk2 ,
droan-b3mgn6 ,
droan-b3mii3 ,
droan-b3mjk2 ,
droan-b3mjk3 ,
droan-b3mjk4 ,
droan-b3mjk5 ,
droan-b3mjl2 ,
droan-b3mjl4 ,
droan-b3mjl7 ,
droan-b3mjl9 ,
droan-b3mjm8 ,
droan-b3mjm9 ,
droan-b3mjs6 ,
droan-b3mkr0 ,
droan-b3ml20 ,
droan-b3mly4 ,
droan-b3mly5 ,
droan-b3mly6 ,
droan-b3mmm8 ,
droan-b3mnb5 ,
droan-b3mny9 ,
droan-b3mtj5 ,
droan-b3muw4 ,
droan-b3muw8 ,
droan-b3n0e7 ,
droan-b3n2j7 ,
droan-b3n247 ,
droan-c5idb2 ,
droer-ACHE ,
droer-b3n5c7 ,
droer-b3n5d0 ,
droer-b3n5d8 ,
droer-b3n5d9 ,
droer-b3n5t7 ,
droer-b3n5y4 ,
droer-b3n7d2 ,
droer-b3n7d3 ,
droer-b3n7d4 ,
droer-b3n7k8 ,
droer-b3n8e4 ,
droer-b3n8f7 ,
droer-b3n8f8 ,
droer-b3n9e1 ,
droer-b3n319 ,
droer-b3n547 ,
droer-b3n549 ,
droer-b3n558 ,
droer-b3n560 ,
droer-b3n577 ,
droer-b3n612 ,
droer-b3nar5 ,
droer-b3nb91 ,
droer-b3nct9 ,
droer-b3nd53 ,
droer-b3ndh9 ,
droer-b3ndq8 ,
droer-b3ne66 ,
droer-b3ne67 ,
droer-b3ne97 ,
droer-b3nfk3 ,
droer-b3nfq9 ,
droer-b3nim7 ,
droer-b3nkn2 ,
droer-b3nm11 ,
droer-b3nmh4 ,
droer-b3nmy2 ,
droer-b3npx2 ,
droer-b3npx3 ,
droer-b3nq76 ,
droer-b3nqg9 ,
droer-b3nqm8 ,
droer-b3nr28 ,
droer-b3nrd3 ,
droer-b3nst4 ,
droer-b3nwa7 ,
droer-b3nyp5.1 ,
droer-b3nyp5.2 ,
droer-b3nyp6 ,
droer-b3nyp7 ,
droer-b3nyp8 ,
droer-b3nyp9 ,
droer-b3nyq3 ,
droer-b3nz06 ,
droer-b3nz14 ,
droer-b3nzj0 ,
droer-b3p0c0 ,
droer-b3p0c1 ,
droer-b3p0c2 ,
droer-b3p2x6 ,
droer-b3p2x7 ,
droer-b3p2x9 ,
droer-b3p2y1 ,
droer-b3p2y2 ,
droer-b3p6d4 ,
droer-b3p6d5 ,
droer-b3p6w3 ,
droer-b3p7b4 ,
droer-b3p7h9 ,
droer-b3p152 ,
droer-b3p486 ,
droer-b3p487 ,
droer-b3p488 ,
droer-b3p489 ,
droer-EST6 ,
droer-q670j5 ,
drogr-ACHE ,
drogr-b4iwp3 ,
drogr-b4iww3 ,
drogr-b4iwy3 ,
drogr-b4ixf7 ,
drogr-b4ixh4 ,
drogr-b4iyz5 ,
drogr-b4j2s2 ,
drogr-b4j2u8 ,
drogr-b4j3u1 ,
drogr-b4j3v3 ,
drogr-b4j4g7 ,
drogr-b4j4x9 ,
drogr-b4j6e6 ,
drogr-b4j9c9 ,
drogr-b4j9y4 ,
drogr-b4j156 ,
drogr-b4j384 ,
drogr-b4j605 ,
drogr-b4j685 ,
drogr-b4ja76 ,
drogr-b4jay5 ,
drogr-b4jcf0 ,
drogr-b4jcf1 ,
drogr-b4jdg6 ,
drogr-b4jdg7 ,
drogr-b4jdh6 ,
drogr-b4jdz1 ,
drogr-b4jdz2 ,
drogr-b4jdz4 ,
drogr-b4je66 ,
drogr-b4je79 ,
drogr-b4je82 ,
drogr-b4je88 ,
drogr-b4je89 ,
drogr-b4je90 ,
drogr-b4je91 ,
drogr-b4jf76 ,
drogr-b4jf79 ,
drogr-b4jf80 ,
drogr-b4jf81 ,
drogr-b4jf82 ,
drogr-b4jf83 ,
drogr-b4jf84 ,
drogr-b4jf85 ,
drogr-b4jf87 ,
drogr-b4jf91 ,
drogr-b4jf92 ,
drogr-b4jg66 ,
drogr-b4jgh0 ,
drogr-b4jgh1 ,
drogr-b4jgr9 ,
drogr-b4ji67 ,
drogr-b4jls2 ,
drogr-b4jnh9 ,
drogr-b4jpc6 ,
drogr-b4jpq3 ,
drogr-b4jpx9 ,
drogr-b4jql2 ,
drogr-b4jrh5 ,
drogr-b4jsb2 ,
drogr-b4jth3 ,
drogr-b4jti1 ,
drogr-b4jul5 ,
drogr-b4jur4 ,
drogr-b4jvh3 ,
drogr-b4jz00 ,
drogr-b4jz03 ,
drogr-b4jz04 ,
drogr-b4jz05 ,
drogr-b4jzh2 ,
drogr-b4k0u2 ,
drogr-b4k2r1 ,
drogr-b4k234 ,
drogr-b4k235 ,
drome-BEM46 ,
drome-CG3734 ,
drome-CG9953 ,
drome-CG11626 ,
drome-GH02439 ,
dromo-ACHE ,
dromo-b4k6a7 ,
dromo-b4k6a8 ,
dromo-b4k6q8 ,
dromo-b4k6q9 ,
dromo-b4k6r1 ,
dromo-b4k6r3 ,
dromo-b4k6r4 ,
dromo-b4k6r5 ,
dromo-b4k6r6 ,
dromo-b4k6r7 ,
dromo-b4k6r8 ,
dromo-b4k6r9 ,
dromo-b4k6s0 ,
dromo-b4k6s1 ,
dromo-b4k6s2 ,
dromo-b4k9c7 ,
dromo-b4k9d3 ,
dromo-b4k571 ,
dromo-b4k721 ,
dromo-b4ka74 ,
dromo-b4ka89 ,
dromo-b4kaj4 ,
dromo-b4kc20 ,
dromo-b4kcl2 ,
dromo-b4kcl3 ,
dromo-b4kd55.1 ,
dromo-b4kd55.2 ,
dromo-b4kd56 ,
dromo-b4kd57 ,
dromo-b4kde1 ,
dromo-b4kdg2 ,
dromo-b4kdh4 ,
dromo-b4kdh5 ,
dromo-b4kdh6 ,
dromo-A0A0Q9XDF2 ,
dromo-b4kdh8.1 ,
dromo-b4kdh8.2 ,
dromo-b4kg04 ,
dromo-b4kg05 ,
dromo-b4kg06 ,
dromo-b4kg16 ,
dromo-b4kg44 ,
dromo-b4kg90 ,
dromo-b4kh20 ,
dromo-b4kh21 ,
dromo-b4kht7 ,
dromo-b4kid3 ,
dromo-b4kik0 ,
dromo-b4kjx0 ,
dromo-b4kki1 ,
dromo-b4kkp6 ,
dromo-b4kkp8 ,
dromo-b4kkq8 ,
dromo-b4kkr0 ,
dromo-b4kkr3 ,
dromo-b4kkr4 ,
dromo-b4kks0 ,
dromo-b4kks1 ,
dromo-b4kks2 ,
dromo-b4kla1 ,
dromo-b4klv8 ,
dromo-b4knt4 ,
dromo-b4kp08 ,
dromo-b4kp16 ,
dromo-b4kqa6 ,
dromo-b4kqa7 ,
dromo-b4kqa8 ,
dromo-b4kqh1 ,
dromo-b4kst4 ,
dromo-b4ksy6 ,
dromo-b4kt84 ,
dromo-b4ktf5 ,
dromo-b4ktf6 ,
dromo-b4kvl3 ,
dromo-b4kvw2 ,
dromo-b4kwv4 ,
dromo-b4kwv5 ,
dromo-b4kxz6 ,
dromo-b4ky12 ,
dromo-b4ky36 ,
dromo-b4ky44 ,
dromo-b4kzu7 ,
dromo-b4l0n8 ,
dromo-b4l4u5 ,
dromo-b4l6l9 ,
dromo-b4l084 ,
drope-ACHE ,
drope-b4g3s6 ,
drope-b4g4p7 ,
drope-b4g6v4 ,
drope-b4g8m0 ,
drope-b4g8n6 ,
drope-b4g8n7 ,
drope-b4g9p2 ,
drope-b4g815 ,
drope-b4g816 ,
drope-b4gat7 ,
drope-b4gav5 ,
drope-b4gb05 ,
drope-b4gc08 ,
drope-b4gcr3 ,
drope-b4gdk2 ,
drope-b4gdl9 ,
drope-b4gdv9 ,
drope-b4gei8 ,
drope-b4gei9 ,
drope-b4gej0 ,
drope-b4ghz9 ,
drope-b4gj62 ,
drope-b4gj64 ,
drope-b4gj74 ,
drope-b4gkf4 ,
drope-b4gkv2 ,
drope-b4gky9 ,
drope-b4gl76 ,
drope-b4glf3 ,
drope-b4gmt3 ,
drope-b4gmt7 ,
drope-b4gmt9 ,
drope-b4gmu2 ,
drope-b4gmu3 ,
drope-b4gmu4 ,
drope-b4gmu5 ,
drope-b4gmu6 ,
drope-b4gmu7 ,
drope-b4gmv1 ,
drope-b4gn08 ,
drope-b4gpa7 ,
drope-b4gq13 ,
drope-b4grh7 ,
drope-b4gsf9 ,
drope-b4gsw4 ,
drope-b4gsw5 ,
drope-b4gsx2 ,
drope-b4gsx7 ,
drope-b4gsy6 ,
drope-b4gsy7 ,
drope-b4guj8 ,
drope-b4gw36 ,
drope-b4gzc2 ,
drope-b4gzc6 ,
drope-b4gzc7 ,
drope-b4h4p9 ,
drope-b4h5l3 ,
drope-b4h6a0 ,
drope-b4h6a8 ,
drope-b4h6a9 ,
drope-b4h6b0 ,
drope-b4h7m7 ,
drope-b4h462 ,
drope-b4h601 ,
drope-b4h602 ,
drope-b4hay1 ,
drope-b4hb18 ,
drope-est5a ,
drope-est5b ,
drope-est5c ,
drops-ACHE ,
drops-b5dhd2 ,
drops-b5dk96 ,
drops-b5dpe3 ,
drops-b5drp9 ,
drops-b5dwa7 ,
drops-b5dwa8 ,
drops-b5dz85 ,
drops-b5dz86 ,
drops-est5a ,
drops-est5b ,
drops-q29bq2 ,
drops-q29dd7 ,
drops-q29ew0 ,
drops-q291d5 ,
drops-q291e8 ,
drops-q293n1 ,
drops-q293n4 ,
drops-q293n5 ,
drops-q293n6 ,
drops-q294n6 ,
drops-q294n7 ,
drops-q294n9 ,
drops-q294p4 ,
drose-b4he97 ,
drose-b4hfu2 ,
drose-b4hg54 ,
drose-b4hga0 ,
drose-b4hgu9 ,
drose-b4hgv0 ,
drose-b4hgv3 ,
drose-b4hgv4 ,
drose-b4hhm8 ,
drose-b4hhs6 ,
drose-b4hie4 ,
drose-b4him9 ,
drose-b4hk63 ,
drose-b4hkj5 ,
drose-b4hr07 ,
drose-b4hr81 ,
drose-b4hre7 ,
drose-b4hs13 ,
drose-b4hsj9 ,
drose-b4hsk0 ,
drose-b4hsm8 ,
drose-b4hvr5 ,
drose-b4hwr7 ,
drose-b4hwr8 ,
drose-b4hwr9 ,
drose-b4hws6 ,
drose-b4hws7 ,
drose-b4hwt0 ,
drose-b4hwt2 ,
drose-b4hwu1 ,
drose-b4hwu2 ,
drose-b4hxs9 ,
drose-b4hxu4 ,
drose-b4hxz1 ,
drose-b4hyp8 ,
drose-b4hyp9 ,
drose-b4hyq0 ,
drose-b4hyz4 ,
drose-b4hyz5 ,
drose-b4i1k8 ,
drose-b4i2f3 ,
drose-b4i2w5 ,
drose-b4i4u3 ,
drose-b4i4u7 ,
drose-b4i4u9 ,
drose-b4i4v0 ,
drose-b4i4v1 ,
drose-b4i4v4 ,
drose-b4i4v5 ,
drose-b4i4v6 ,
drose-b4i4v7 ,
drose-b4i4v8 ,
drose-b4i4w0 ,
drose-b4i7s6 ,
drose-b4i133 ,
drose-b4i857 ,
drose-b4iam7 ,
drose-b4iam9 ,
drose-b4iaq6 ,
drose-b4icf6 ,
drose-b4icf7 ,
drose-b4id80 ,
drose-b4ifc5 ,
drose-b4ihv9 ,
drose-b4iie9 ,
drose-b4ilj8 ,
drose-b4in13 ,
drose-b4inj9 ,
drosi-ACHE ,
drosi-aes04a ,
drosi-b4nsh8 ,
drosi-b4q3d7 ,
drosi-b4q4w5 ,
drosi-b4q4y7 ,
drosi-b4q6h6 ,
drosi-b4q7u2 ,
drosi-b4q7u3 ,
drosi-b4q9c6 ,
drosi-b4q9c7 ,
drosi-b4q9d3 ,
drosi-b4q9d4 ,
drosi-b4q9r0 ,
drosi-b4q9r1 ,
drosi-b4q9r3 ,
drosi-b4q9s2 ,
drosi-b4q9s3 ,
drosi-b4q429 ,
drosi-b4q530 ,
drosi-b4q734 ,
drosi-b4q782 ,
drosi-b4q783 ,
drosi-b4q942 ,
drosi-b4qet1 ,
drosi-b4qfv6 ,
drosi-b4qge5 ,
drosi-b4qgh5 ,
drosi-b4qgs5 ,
drosi-b4qhf3 ,
drosi-b4qhf4 ,
drosi-b4qhi5 ,
drosi-b4qjr2 ,
drosi-b4qjr3 ,
drosi-b4qjv6 ,
drosi-b4qk23 ,
drosi-b4qk51 ,
drosi-b4qlt1 ,
drosi-b4qlz9 ,
drosi-b4qmn9 ,
drosi-b4qrq7 ,
drosi-b4qs01 ,
drosi-b4qs57 ,
drosi-b4qs82 ,
drosi-b4qs83 ,
drosi-b4qs84 ,
drosi-b4qs85 ,
drosi-b4qs86 ,
drosi-b4qsq1 ,
drosi-b4quk6 ,
drosi-b4qvg5 ,
drosi-b4qvg6 ,
drosi-b4qzn2 ,
drosi-b4qzn3 ,
drosi-b4qzn5 ,
drosi-b4qzn7 ,
drosi-b4qzn8 ,
drosi-b4qzp2 ,
drosi-b4qzp3 ,
drosi-b4qzp4 ,
drosi-b4qzp5 ,
drosi-b4qzp6 ,
drosi-b4qzp7 ,
drosi-b4r1a4 ,
drosi-b4r025 ,
drosi-b4r207 ,
drosi-b4r662 ,
drosi-este6 ,
drosi-q670k8 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lf33 ,
drovi-b4lf51 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgc6 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgk5 ,
drovi-b4lgn2 ,
drovi-b4lh17 ,
drovi-b4lh18 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4llm5 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lnr4 ,
drovi-b4lp47 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lqc6 ,
drovi-b4lr00 ,
drovi-b4lrp6 ,
drovi-b4lrw2 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lsq5 ,
drovi-b4lt32 ,
drovi-b4ltr1 ,
drovi-b4lui7 ,
drovi-b4lui9 ,
drovi-b4luj8 ,
drovi-b4luk0 ,
drovi-b4luk3 ,
drovi-b4luk8 ,
drovi-b4luk9 ,
drovi-b4lul0 ,
drovi-b4lve2 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4lyq2 ,
drovi-b4lyq3 ,
drovi-b4lz07 ,
drovi-b4lz13 ,
drovi-b4lz14 ,
drovi-b4lz15 ,
drovi-b4m0j7 ,
drovi-b4m0s0 ,
drovi-b4m2b6 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m6b9 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m564 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mb87 ,
drovi-b4mc71 ,
drovi-b4mfa4 ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mkt7 ,
drowi-b4mlc1 ,
drowi-b4mp68 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrd1 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4muj8 ,
drowi-b4mv18 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwp2 ,
drowi-b4mwp6 ,
drowi-b4mwq5 ,
drowi-b4mwr0 ,
drowi-b4mwr8 ,
drowi-b4mwr9 ,
drowi-b4mwt1 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myg1 ,
drowi-b4myh5 ,
drowi-b4n0d4 ,
drowi-b4n1a7 ,
drowi-b4n1c8 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n4x9 ,
drowi-b4n4y0 ,
drowi-b4n6m1 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4nae3 ,
drowi-b4ner8 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4nhz9 ,
drowi-b4nj18 ,
drowi-b4nj19 ,
drowi-b4nja7 ,
drowi-b4nja8 ,
drowi-b4nja9 ,
drowi-b4njk8 ,
drowi-b4nkc8 ,
drowi-b4nky0 ,
drowi-b4nl36 ,
drowi-b4nm27 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-ACHE ,
droya-aes04 ,
droya-b4itg2 ,
droya-b4itg6 ,
droya-b4itu9 ,
droya-b4iuv4 ,
droya-b4iuv5 ,
droya-b4nxe6 ,
droya-b4nxg5 ,
droya-b4nxg6 ,
droya-b4nxg8 ,
droya-b4nxw4 ,
droya-b4ny57 ,
droya-b4ny58 ,
droya-b4ny86 ,
droya-b4nzz8 ,
droya-b4p0b5 ,
droya-b4p0q9 ,
droya-b4p0r0 ,
droya-b4p0r7 ,
droya-b4p0r8 ,
droya-b4p0r9 ,
droya-b4p0s0 ,
droya-b4p0s2 ,
droya-b4p0t0 ,
droya-b4p0t1 ,
droya-b4p3h4 ,
droya-b4p3x8 ,
droya-b4p5g8 ,
droya-b4p6c9 ,
droya-b4p6l9 ,
droya-b4p6r1 ,
droya-b4p6r2 ,
droya-b4p7u4 ,
droya-b4p8w7 ,
droya-b4p023 ,
droya-b4p241 ,
droya-b4p774 ,
droya-b4pat9 ,
droya-b4pbl1 ,
droya-b4pd22 ,
droya-b4pd70 ,
droya-b4pdm8 ,
droya-b4pet9 ,
droya-b4pff9 ,
droya-b4pga7 ,
droya-b4pgu0 ,
droya-b4pig3 ,
droya-b4pjt8 ,
droya-b4pka2 ,
droya-b4plh2 ,
droya-b4pma3 ,
droya-b4pmv3 ,
droya-b4pmv4 ,
droya-b4pmv5 ,
droya-b4pn92 ,
droya-b4pp65 ,
droya-b4ppc5 ,
droya-b4ppc6 ,
droya-b4ppc7 ,
droya-b4ppc8 ,
droya-b4pq03 ,
droya-b4prg6B ,
droya-b4prg9 ,
droya-b4prh3 ,
droya-b4prh4 ,
droya-b4prh6 ,
droya-b4prh7 ,
droya-b4psz8 ,
droya-b4psz9 ,
droya-b4pv22 ,
droya-b4q0g5 ,
droya-b4q246 ,
droya-EST6 ,
droya-q71d76 ,
drowi-b4n7m9 ,
drope-b4gkk1 ,
droer-b3n5s3 ,
drose-b4i1w5 ,
drowi-a0a0q9x0t3 ,
drogr-b4jvm7 ,
dromo-b4ku70 ,
drovi-b4mcn9 ,
drovi-b4lty2 ,
drogr-b4jdu1 ,
drovi-a0a0q9wiq8 ,
dromo-b4kf70 ,
drosi-b2zi86 ,
droya-b4p2y4 ,
drose-b2zic5 ,
droer-b3n895 Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
Title: An evolutionary analysis of orphan genes in DrosophilaDomazet-Loso T , Tautz D Ref: Genome Res, 13 :2213, 2003 : PubMed Abstract ESTHER: Domazet-Loso_2003_Genome.Res_13_2213 PubMedSearch: Domazet-Loso 2003 Genome.Res 13 2213 PubMedID: 14525923 Gene_locus related to this paper: droya-b4p7u4 ,
droya-q71d76 Abstract
Orphan genes are protein-coding regions that have no recognizable homolog in distantly related species. A substantial fraction of coding regions in any genome sequenced consists of orphan genes, but the evolutionary and functional significance of orphan genes is not understood. We present a reanalysis of the Drosophila melanogaster proteome that shows that there are still between 26% and 29% of all proteins without a significant match with noninsect sequences, and that these orphans are underrepresented in genetic screens. To analyze the characteristics of orphan genes in Drosophila, we used sequence comparisons between cDNAs retrieved from two Drosophila yakuba libraries and their corresponding D. melanogaster orthologs. We find that a cDNA library from adults yields twice as many orphan genes as such a library from embryos. The orphan genes evolve on average more than three times faster than nonorphan genes, although the width of the evolutionary rate distribution is similar for the two classes. In particular, some orphan genes show very low substitution rates that are comparable to otherwise highly conserved genes. We propose a model suggesting that orphans may be involved in the evolution of adaptive traits, and that slow-evolving orphan genes may be particularly interesting candidate genes for identifying lineage-specific adaptations.
Title: Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genomeBergman CM , Pfeiffer BD , Rincon-Limas DE , Hoskins RA , Gnirke A , Mungall CJ , Wang AM , Kronmiller B , Pacleb J and Celniker SE <7 more author(s)> Bergman CM , Pfeiffer BD , Rincon-Limas DE , Hoskins RA , Gnirke A , Mungall CJ , Wang AM , Kronmiller B , Pacleb J , Park S , Stapleton M , Wan K , George RA , de Jong PJ , Botas J , Rubin GM , Celniker SE (- 7) Ref: Genome Biol, 3 :RESEARCH0086, 2002 : PubMed Abstract ESTHER: Bergman_2002_Genome.Biol_3_RESEARCH0086 PubMedSearch: Bergman 2002 Genome.Biol 3 RESEARCH0086 PubMedID: 12537575 Gene_locus related to this paper: drops-CG4390 ,
drowi-b4ngb5 ,
droya-q71d76 Abstract
BACKGROUND: It is widely accepted that comparative sequence data can aid the functional annotation of genome sequences; however, the most informative species and features of genome evolution for comparison remain to be determined. 1 less
Title: Assembly reconciliationZimin AV , Smith DR , Sutton G , Yorke JA Ref: Bioinformatics, 24 :42, 2008 : PubMed Abstract ESTHER: Zimin_2008_Bioinformatics_24_42 PubMedSearch: Zimin 2008 Bioinformatics 24 42 PubMedID: 18057021 Gene_locus related to this paper: droan-ACHE ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
droan-b3lyh7 ,
droan-b3lyh9 ,
droan-b3lyi0 ,
droan-b3lyi2 ,
droan-b3lyi3 ,
droan-b3lyi4 ,
droan-b3lyx4 ,
droan-b3lyx5 ,
droan-b3lyx6 ,
droan-b3lyx7 ,
droan-b3lyx9 ,
droan-b3lz72 ,
droan-b3m4e3 ,
droan-b3m5w1 ,
droan-b3m6i7 ,
droan-b3m7v2 ,
droan-b3m9p3 ,
droan-b3m524 ,
droan-b3m635 ,
droan-b3mdh7 ,
droan-b3mdw8 ,
droan-b3mee1 ,
droan-b3mf47 ,
droan-b3mf48 ,
droan-b3mg94 ,
droan-b3mgn6 ,
droan-b3mii3 ,
droan-b3mkr0 ,
droan-b3ml20 ,
droan-b3mly4 ,
droan-b3mly5 ,
droan-b3mly6 ,
droan-b3mnb5 ,
droan-b3muw4 ,
droan-b3muw8 ,
droan-b3n2j7 ,
droan-c5idb2 ,
droer-ACHE ,
droer-b3n5y4 ,
droer-b3n7d2 ,
droer-b3n7d3 ,
droer-b3n7d4 ,
droer-b3n7k8 ,
droer-b3n8e4 ,
droer-b3n8f7 ,
droer-b3n8f8 ,
droer-b3n9e1 ,
droer-b3n612 ,
droer-b3nar5 ,
droer-b3nb91 ,
droer-b3nct9 ,
droer-b3ndh9 ,
droer-b3ndq8 ,
droer-b3ne97 ,
droer-b3nfq9 ,
droer-b3nmh4 ,
droer-b3nmy2 ,
droer-b3npx2 ,
droer-b3npx3 ,
droer-b3nq76 ,
droer-b3nr28 ,
droer-b3nst4 ,
droer-b3nyp5.1 ,
droer-b3nyp5.2 ,
droer-b3nyp6 ,
droer-b3nyp7 ,
droer-b3nyp8 ,
droer-b3nyp9 ,
droer-b3nyq3 ,
droer-b3nz06 ,
droer-b3nz14 ,
droer-b3nzj0 ,
droer-b3p2x6 ,
droer-b3p2x7 ,
droer-b3p2x9 ,
droer-b3p2y1 ,
droer-b3p2y2 ,
droer-b3p7b4 ,
droer-EST6 ,
droer-q670j5 ,
drogr-ACHE ,
drogr-b4iww3 ,
drogr-b4iwy3 ,
drogr-b4ixf7 ,
drogr-b4ixh4 ,
drogr-b4j2u8 ,
drogr-b4j3v3 ,
drogr-b4j4g7 ,
drogr-b4j4x9 ,
drogr-b4j6e6 ,
drogr-b4j9c9 ,
drogr-b4j9y4 ,
drogr-b4j156 ,
drogr-b4j685 ,
drogr-b4ja76 ,
drogr-b4jcf0 ,
drogr-b4jcf1 ,
drogr-b4jdh6 ,
drogr-b4jdz1 ,
drogr-b4jdz2 ,
drogr-b4jdz4 ,
drogr-b4jf76 ,
drogr-b4jf79 ,
drogr-b4jf80 ,
drogr-b4jf81 ,
drogr-b4jf82 ,
drogr-b4jf83 ,
drogr-b4jf84 ,
drogr-b4jf85 ,
drogr-b4jf87 ,
drogr-b4jf91 ,
drogr-b4jf92 ,
drogr-b4jg66 ,
drogr-b4jnh9 ,
drogr-b4jpc6 ,
drogr-b4jql2 ,
drogr-b4jrh5 ,
drogr-b4jth3 ,
drogr-b4jti1 ,
drogr-b4jul5 ,
dromo-ACHE ,
dromo-b4k6q8 ,
dromo-b4k6q9 ,
dromo-b4k6r1 ,
dromo-b4k6r3 ,
dromo-b4k6r4 ,
dromo-b4k6r5 ,
dromo-b4k6r6 ,
dromo-b4k6r7 ,
dromo-b4k6r8 ,
dromo-b4k6r9 ,
dromo-b4k6s0 ,
dromo-b4k6s1 ,
dromo-b4k6s2 ,
dromo-b4k9c7 ,
dromo-b4k9d3 ,
dromo-b4ka74 ,
dromo-b4kaj4 ,
dromo-b4kdg2 ,
dromo-b4kdh4 ,
dromo-b4kdh5 ,
dromo-b4kdh6 ,
dromo-A0A0Q9XDF2 ,
dromo-b4kdh8.1 ,
dromo-b4kdh8.2 ,
dromo-b4kg04 ,
dromo-b4kg05 ,
dromo-b4kg06 ,
dromo-b4kg16 ,
dromo-b4kh20 ,
dromo-b4kh21 ,
dromo-b4kik0 ,
dromo-b4kjx0 ,
dromo-b4kki1 ,
dromo-b4klv8 ,
dromo-b4kp08 ,
dromo-b4kqa6 ,
dromo-b4kqa7 ,
dromo-b4kqa8 ,
dromo-b4kqh1 ,
dromo-b4kst4 ,
dromo-b4ksy6 ,
dromo-b4ktf5 ,
dromo-b4ktf6 ,
dromo-b4kvw2 ,
dromo-b4kxz6 ,
dromo-b4ky12 ,
dromo-b4ky36 ,
dromo-b4l0n8 ,
dromo-b4l6l9 ,
dromo-b4l084 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgn2 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lrp6 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lt32 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4m0s0 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mfa4 ,
drovi-estes ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myh5 ,
drowi-b4n1a7 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4njk8 ,
drowi-b4nky0 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-q71d76 ,
drowi-a0a0q9x0t3 ,
drovi-b4mcn9 Abstract
MOTIVATION: Many genomes are sequenced by a collaboration of several centers, and then each center produces an assembly using their own assembly software. The collaborators then pick the draft assembly that they judge to be the best and the information contained in the other assemblies is usually not used. METHODS: We have developed a technique that we call assembly reconciliation that can merge draft genome assemblies. It takes one draft assembly, detects apparent errors, and, when possible, patches the problem areas using pieces from alternative draft assemblies. It also closes gaps in places where one of the alternative assemblies has spanned the gap correctly. RESULTS: Using the Assembly Reconciliation technique, we produced reconciled assemblies of six Drosophila species in collaboration with Agencourt Bioscience and The J. Craig Venter Institute. These assemblies are now the official (CAF1) assemblies used for analysis. We also produced a reconciled assembly of Rhesus Macaque genome, and this assembly is available from our website http://www.genome.umd.edu. AVAILABILITY: The reconciliation software is available for download from http://www.genome.umd.edu/software.htm
Title: Evolution of genes and genomes on the Drosophila phylogenyClark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W and MacCallum I <405 more author(s)> Clark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W , Iyer VN , Pollard DA , Sackton TB , Larracuente AM , Singh ND , Abad JP , Abt DN , Adryan B , Aguade M , Akashi H , Anderson WW , Aquadro CF , Ardell DH , Arguello R , Artieri CG , Barbash DA , Barker D , Barsanti P , Batterham P , Batzoglou S , Begun D , Bhutkar A , Blanco E , Bosak SA , Bradley RK , Brand AD , Brent MR , Brooks AN , Brown RH , Butlin RK , Caggese C , Calvi BR , Bernardo de Carvalho A , Caspi A , Castrezana S , Celniker SE , Chang JL , Chapple C , Chatterji S , Chinwalla A , Civetta A , Clifton SW , Comeron JM , Costello JC , Coyne JA , Daub J , David RG , Delcher AL , Delehaunty K , Do CB , Ebling H , Edwards K , Eickbush T , Evans JD , Filipski A , Findeiss S , Freyhult E , Fulton L , Fulton R , Garcia AC , Gardiner A , Garfield DA , Garvin BE , Gibson G , Gilbert D , Gnerre S , Godfrey J , Good R , Gotea V , Gravely B , Greenberg AJ , Griffiths-Jones S , Gross S , Guigo R , Gustafson EA , Haerty W , Hahn MW , Halligan DL , Halpern AL , Halter GM , Han MV , Heger A , Hillier L , Hinrichs AS , Holmes I , Hoskins RA , Hubisz MJ , Hultmark D , Huntley MA , Jaffe DB , Jagadeeshan S , Jeck WR , Johnson J , Jones CD , Jordan WC , Karpen GH , Kataoka E , Keightley PD , Kheradpour P , Kirkness EF , Koerich LB , Kristiansen K , Kudrna D , Kulathinal RJ , Kumar S , Kwok R , Lander E , Langley CH , Lapoint R , Lazzaro BP , Lee SJ , Levesque L , Li R , Lin CF , Lin MF , Lindblad-Toh K , Llopart A , Long M , Low L , Lozovsky E , Lu J , Luo M , Machado CA , Makalowski W , Marzo M , Matsuda M , Matzkin L , McAllister B , McBride CS , McKernan B , McKernan K , Mendez-Lago M , Minx P , Mollenhauer MU , Montooth K , Mount SM , Mu X , Myers E , Negre B , Newfeld S , Nielsen R , Noor MA , O'Grady P , Pachter L , Papaceit M , Parisi MJ , Parisi M , Parts L , Pedersen JS , Pesole G , Phillippy AM , Ponting CP , Pop M , Porcelli D , Powell JR , Prohaska S , Pruitt K , Puig M , Quesneville H , Ram KR , Rand D , Rasmussen MD , Reed LK , Reenan R , Reily A , Remington KA , Rieger TT , Ritchie MG , Robin C , Rogers YH , Rohde C , Rozas J , Rubenfield MJ , Ruiz A , Russo S , Salzberg SL , Sanchez-Gracia A , Saranga DJ , Sato H , Schaeffer SW , Schatz MC , Schlenke T , Schwartz R , Segarra C , Singh RS , Sirot L , Sirota M , Sisneros NB , Smith CD , Smith TF , Spieth J , Stage DE , Stark A , Stephan W , Strausberg RL , Strempel S , Sturgill D , Sutton G , Sutton GG , Tao W , Teichmann S , Tobari YN , Tomimura Y , Tsolas JM , Valente VL , Venter E , Venter JC , Vicario S , Vieira FG , Vilella AJ , Villasante A , Walenz B , Wang J , Wasserman M , Watts T , Wilson D , Wilson RK , Wing RA , Wolfner MF , Wong A , Wong GK , Wu CI , Wu G , Yamamoto D , Yang HP , Yang SP , Yorke JA , Yoshida K , Zdobnov E , Zhang P , Zhang Y , Zimin AV , Baldwin J , Abdouelleil A , Abdulkadir J , Abebe A , Abera B , Abreu J , Acer SC , Aftuck L , Alexander A , An P , Anderson E , Anderson S , Arachi H , Azer M , Bachantsang P , Barry A , Bayul T , Berlin A , Bessette D , Bloom T , Blye J , Boguslavskiy L , Bonnet C , Boukhgalter B , Bourzgui I , Brown A , Cahill P , Channer S , Cheshatsang Y , Chuda L , Citroen M , Collymore A , Cooke P , Costello M , D'Aco K , Daza R , De Haan G , DeGray S , DeMaso C , Dhargay N , Dooley K , Dooley E , Doricent M , Dorje P , Dorjee K , Dupes A , Elong R , Falk J , Farina A , Faro S , Ferguson D , Fisher S , Foley CD , Franke A , Friedrich D , Gadbois L , Gearin G , Gearin CR , Giannoukos G , Goode T , Graham J , Grandbois E , Grewal S , Gyaltsen K , Hafez N , Hagos B , Hall J , Henson C , Hollinger A , Honan T , Huard MD , Hughes L , Hurhula B , Husby ME , Kamat A , Kanga B , Kashin S , Khazanovich D , Kisner P , Lance K , Lara M , Lee W , Lennon N , Letendre F , LeVine R , Lipovsky A , Liu X , Liu J , Liu S , Lokyitsang T , Lokyitsang Y , Lubonja R , Lui A , Macdonald P , Magnisalis V , Maru K , Matthews C , McCusker W , McDonough S , Mehta T , Meldrim J , Meneus L , Mihai O , Mihalev A , Mihova T , Mittelman R , Mlenga V , Montmayeur A , Mulrain L , Navidi A , Naylor J , Negash T , Nguyen T , Nguyen N , Nicol R , Norbu C , Norbu N , Novod N , O'Neill B , Osman S , Markiewicz E , Oyono OL , Patti C , Phunkhang P , Pierre F , Priest M , Raghuraman S , Rege F , Reyes R , Rise C , Rogov P , Ross K , Ryan E , Settipalli S , Shea T , Sherpa N , Shi L , Shih D , Sparrow T , Spaulding J , Stalker J , Stange-Thomann N , Stavropoulos S , Stone C , Strader C , Tesfaye S , Thomson T , Thoulutsang Y , Thoulutsang D , Topham K , Topping I , Tsamla T , Vassiliev H , Vo A , Wangchuk T , Wangdi T , Weiand M , Wilkinson J , Wilson A , Yadav S , Young G , Yu Q , Zembek L , Zhong D , Zimmer A , Zwirko Z , Alvarez P , Brockman W , Butler J , Chin C , Grabherr M , Kleber M , Mauceli E , MacCallum I (- 405) Ref: Nature, 450 :203, 2007 : PubMed Abstract ESTHER: Clark_2007_Nature_450_203 PubMedSearch: Clark 2007 Nature 450 203 PubMedID: 17994087 Gene_locus related to this paper: droan-ACHE ,
droan-b3lx10 ,
droan-b3lx75 ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
droan-b3lyh7 ,
droan-b3lyh9 ,
droan-b3lyi0 ,
droan-b3lyi2 ,
droan-b3lyi3 ,
droan-b3lyi4 ,
droan-b3lyj8 ,
droan-b3lyj9 ,
droan-b3lyx4 ,
droan-b3lyx5 ,
droan-b3lyx6 ,
droan-b3lyx7 ,
droan-b3lyx9 ,
droan-b3lz72 ,
droan-b3m1x3 ,
droan-b3m2d4 ,
droan-b3m3d9 ,
droan-b3m4e3 ,
droan-b3m5w1 ,
droan-b3m6i7 ,
droan-b3m7v2 ,
droan-b3m9a5 ,
droan-b3m9f4 ,
droan-b3m9p3 ,
droan-b3m254 ,
droan-b3m259 ,
droan-b3m260 ,
droan-b3m262 ,
droan-b3m524 ,
droan-b3m635 ,
droan-b3m845 ,
droan-b3m846 ,
droan-b3md01 ,
droan-b3mdh7 ,
droan-b3mdm6 ,
droan-b3mdw8 ,
droan-b3mee1 ,
droan-b3mf47 ,
droan-b3mf48 ,
droan-b3mg94 ,
droan-b3mgk2 ,
droan-b3mgn6 ,
droan-b3mii3 ,
droan-b3mjk2 ,
droan-b3mjk3 ,
droan-b3mjk4 ,
droan-b3mjk5 ,
droan-b3mjl2 ,
droan-b3mjl4 ,
droan-b3mjl7 ,
droan-b3mjl9 ,
droan-b3mjm8 ,
droan-b3mjm9 ,
droan-b3mjs6 ,
droan-b3mkr0 ,
droan-b3ml20 ,
droan-b3mly4 ,
droan-b3mly5 ,
droan-b3mly6 ,
droan-b3mmm8 ,
droan-b3mnb5 ,
droan-b3mny9 ,
droan-b3mtj5 ,
droan-b3muw4 ,
droan-b3muw8 ,
droan-b3n0e7 ,
droan-b3n2j7 ,
droan-b3n247 ,
droan-c5idb2 ,
droer-ACHE ,
droer-b3n5c7 ,
droer-b3n5d0 ,
droer-b3n5d8 ,
droer-b3n5d9 ,
droer-b3n5t7 ,
droer-b3n5y4 ,
droer-b3n7d2 ,
droer-b3n7d3 ,
droer-b3n7d4 ,
droer-b3n7k8 ,
droer-b3n8e4 ,
droer-b3n8f7 ,
droer-b3n8f8 ,
droer-b3n9e1 ,
droer-b3n319 ,
droer-b3n547 ,
droer-b3n549 ,
droer-b3n558 ,
droer-b3n560 ,
droer-b3n577 ,
droer-b3n612 ,
droer-b3nar5 ,
droer-b3nb91 ,
droer-b3nct9 ,
droer-b3nd53 ,
droer-b3ndh9 ,
droer-b3ndq8 ,
droer-b3ne66 ,
droer-b3ne67 ,
droer-b3ne97 ,
droer-b3nfk3 ,
droer-b3nfq9 ,
droer-b3nim7 ,
droer-b3nkn2 ,
droer-b3nm11 ,
droer-b3nmh4 ,
droer-b3nmy2 ,
droer-b3npx2 ,
droer-b3npx3 ,
droer-b3nq76 ,
droer-b3nqg9 ,
droer-b3nqm8 ,
droer-b3nr28 ,
droer-b3nrd3 ,
droer-b3nst4 ,
droer-b3nwa7 ,
droer-b3nyp5.1 ,
droer-b3nyp5.2 ,
droer-b3nyp6 ,
droer-b3nyp7 ,
droer-b3nyp8 ,
droer-b3nyp9 ,
droer-b3nyq3 ,
droer-b3nz06 ,
droer-b3nz14 ,
droer-b3nzj0 ,
droer-b3p0c0 ,
droer-b3p0c1 ,
droer-b3p0c2 ,
droer-b3p2x6 ,
droer-b3p2x7 ,
droer-b3p2x9 ,
droer-b3p2y1 ,
droer-b3p2y2 ,
droer-b3p6d4 ,
droer-b3p6d5 ,
droer-b3p6w3 ,
droer-b3p7b4 ,
droer-b3p7h9 ,
droer-b3p152 ,
droer-b3p486 ,
droer-b3p487 ,
droer-b3p488 ,
droer-b3p489 ,
droer-EST6 ,
droer-q670j5 ,
drogr-ACHE ,
drogr-b4iwp3 ,
drogr-b4iww3 ,
drogr-b4iwy3 ,
drogr-b4ixf7 ,
drogr-b4ixh4 ,
drogr-b4iyz5 ,
drogr-b4j2s2 ,
drogr-b4j2u8 ,
drogr-b4j3u1 ,
drogr-b4j3v3 ,
drogr-b4j4g7 ,
drogr-b4j4x9 ,
drogr-b4j6e6 ,
drogr-b4j9c9 ,
drogr-b4j9y4 ,
drogr-b4j156 ,
drogr-b4j384 ,
drogr-b4j605 ,
drogr-b4j685 ,
drogr-b4ja76 ,
drogr-b4jay5 ,
drogr-b4jcf0 ,
drogr-b4jcf1 ,
drogr-b4jdg6 ,
drogr-b4jdg7 ,
drogr-b4jdh6 ,
drogr-b4jdz1 ,
drogr-b4jdz2 ,
drogr-b4jdz4 ,
drogr-b4je66 ,
drogr-b4je79 ,
drogr-b4je82 ,
drogr-b4je88 ,
drogr-b4je89 ,
drogr-b4je90 ,
drogr-b4je91 ,
drogr-b4jf76 ,
drogr-b4jf79 ,
drogr-b4jf80 ,
drogr-b4jf81 ,
drogr-b4jf82 ,
drogr-b4jf83 ,
drogr-b4jf84 ,
drogr-b4jf85 ,
drogr-b4jf87 ,
drogr-b4jf91 ,
drogr-b4jf92 ,
drogr-b4jg66 ,
drogr-b4jgh0 ,
drogr-b4jgh1 ,
drogr-b4jgr9 ,
drogr-b4ji67 ,
drogr-b4jls2 ,
drogr-b4jnh9 ,
drogr-b4jpc6 ,
drogr-b4jpq3 ,
drogr-b4jpx9 ,
drogr-b4jql2 ,
drogr-b4jrh5 ,
drogr-b4jsb2 ,
drogr-b4jth3 ,
drogr-b4jti1 ,
drogr-b4jul5 ,
drogr-b4jur4 ,
drogr-b4jvh3 ,
drogr-b4jz00 ,
drogr-b4jz03 ,
drogr-b4jz04 ,
drogr-b4jz05 ,
drogr-b4jzh2 ,
drogr-b4k0u2 ,
drogr-b4k2r1 ,
drogr-b4k234 ,
drogr-b4k235 ,
drome-BEM46 ,
drome-CG3734 ,
drome-CG9953 ,
drome-CG11626 ,
drome-GH02439 ,
dromo-ACHE ,
dromo-b4k6a7 ,
dromo-b4k6a8 ,
dromo-b4k6q8 ,
dromo-b4k6q9 ,
dromo-b4k6r1 ,
dromo-b4k6r3 ,
dromo-b4k6r4 ,
dromo-b4k6r5 ,
dromo-b4k6r6 ,
dromo-b4k6r7 ,
dromo-b4k6r8 ,
dromo-b4k6r9 ,
dromo-b4k6s0 ,
dromo-b4k6s1 ,
dromo-b4k6s2 ,
dromo-b4k9c7 ,
dromo-b4k9d3 ,
dromo-b4k571 ,
dromo-b4k721 ,
dromo-b4ka74 ,
dromo-b4ka89 ,
dromo-b4kaj4 ,
dromo-b4kc20 ,
dromo-b4kcl2 ,
dromo-b4kcl3 ,
dromo-b4kd55.1 ,
dromo-b4kd55.2 ,
dromo-b4kd56 ,
dromo-b4kd57 ,
dromo-b4kde1 ,
dromo-b4kdg2 ,
dromo-b4kdh4 ,
dromo-b4kdh5 ,
dromo-b4kdh6 ,
dromo-A0A0Q9XDF2 ,
dromo-b4kdh8.1 ,
dromo-b4kdh8.2 ,
dromo-b4kg04 ,
dromo-b4kg05 ,
dromo-b4kg06 ,
dromo-b4kg16 ,
dromo-b4kg44 ,
dromo-b4kg90 ,
dromo-b4kh20 ,
dromo-b4kh21 ,
dromo-b4kht7 ,
dromo-b4kid3 ,
dromo-b4kik0 ,
dromo-b4kjx0 ,
dromo-b4kki1 ,
dromo-b4kkp6 ,
dromo-b4kkp8 ,
dromo-b4kkq8 ,
dromo-b4kkr0 ,
dromo-b4kkr3 ,
dromo-b4kkr4 ,
dromo-b4kks0 ,
dromo-b4kks1 ,
dromo-b4kks2 ,
dromo-b4kla1 ,
dromo-b4klv8 ,
dromo-b4knt4 ,
dromo-b4kp08 ,
dromo-b4kp16 ,
dromo-b4kqa6 ,
dromo-b4kqa7 ,
dromo-b4kqa8 ,
dromo-b4kqh1 ,
dromo-b4kst4 ,
dromo-b4ksy6 ,
dromo-b4kt84 ,
dromo-b4ktf5 ,
dromo-b4ktf6 ,
dromo-b4kvl3 ,
dromo-b4kvw2 ,
dromo-b4kwv4 ,
dromo-b4kwv5 ,
dromo-b4kxz6 ,
dromo-b4ky12 ,
dromo-b4ky36 ,
dromo-b4ky44 ,
dromo-b4kzu7 ,
dromo-b4l0n8 ,
dromo-b4l4u5 ,
dromo-b4l6l9 ,
dromo-b4l084 ,
drope-ACHE ,
drope-b4g3s6 ,
drope-b4g4p7 ,
drope-b4g6v4 ,
drope-b4g8m0 ,
drope-b4g8n6 ,
drope-b4g8n7 ,
drope-b4g9p2 ,
drope-b4g815 ,
drope-b4g816 ,
drope-b4gat7 ,
drope-b4gav5 ,
drope-b4gb05 ,
drope-b4gc08 ,
drope-b4gcr3 ,
drope-b4gdk2 ,
drope-b4gdl9 ,
drope-b4gdv9 ,
drope-b4gei8 ,
drope-b4gei9 ,
drope-b4gej0 ,
drope-b4ghz9 ,
drope-b4gj62 ,
drope-b4gj64 ,
drope-b4gj74 ,
drope-b4gkf4 ,
drope-b4gkv2 ,
drope-b4gky9 ,
drope-b4gl76 ,
drope-b4glf3 ,
drope-b4gmt3 ,
drope-b4gmt7 ,
drope-b4gmt9 ,
drope-b4gmu2 ,
drope-b4gmu3 ,
drope-b4gmu4 ,
drope-b4gmu5 ,
drope-b4gmu6 ,
drope-b4gmu7 ,
drope-b4gmv1 ,
drope-b4gn08 ,
drope-b4gpa7 ,
drope-b4gq13 ,
drope-b4grh7 ,
drope-b4gsf9 ,
drope-b4gsw4 ,
drope-b4gsw5 ,
drope-b4gsx2 ,
drope-b4gsx7 ,
drope-b4gsy6 ,
drope-b4gsy7 ,
drope-b4guj8 ,
drope-b4gw36 ,
drope-b4gzc2 ,
drope-b4gzc6 ,
drope-b4gzc7 ,
drope-b4h4p9 ,
drope-b4h5l3 ,
drope-b4h6a0 ,
drope-b4h6a8 ,
drope-b4h6a9 ,
drope-b4h6b0 ,
drope-b4h7m7 ,
drope-b4h462 ,
drope-b4h601 ,
drope-b4h602 ,
drope-b4hay1 ,
drope-b4hb18 ,
drope-est5a ,
drope-est5b ,
drope-est5c ,
drops-ACHE ,
drops-b5dhd2 ,
drops-b5dk96 ,
drops-b5dpe3 ,
drops-b5drp9 ,
drops-b5dwa7 ,
drops-b5dwa8 ,
drops-b5dz85 ,
drops-b5dz86 ,
drops-est5a ,
drops-est5b ,
drops-q29bq2 ,
drops-q29dd7 ,
drops-q29ew0 ,
drops-q291d5 ,
drops-q291e8 ,
drops-q293n1 ,
drops-q293n4 ,
drops-q293n5 ,
drops-q293n6 ,
drops-q294n6 ,
drops-q294n7 ,
drops-q294n9 ,
drops-q294p4 ,
drose-b4he97 ,
drose-b4hfu2 ,
drose-b4hg54 ,
drose-b4hga0 ,
drose-b4hgu9 ,
drose-b4hgv0 ,
drose-b4hgv3 ,
drose-b4hgv4 ,
drose-b4hhm8 ,
drose-b4hhs6 ,
drose-b4hie4 ,
drose-b4him9 ,
drose-b4hk63 ,
drose-b4hkj5 ,
drose-b4hr07 ,
drose-b4hr81 ,
drose-b4hre7 ,
drose-b4hs13 ,
drose-b4hsj9 ,
drose-b4hsk0 ,
drose-b4hsm8 ,
drose-b4hvr5 ,
drose-b4hwr7 ,
drose-b4hwr8 ,
drose-b4hwr9 ,
drose-b4hws6 ,
drose-b4hws7 ,
drose-b4hwt0 ,
drose-b4hwt2 ,
drose-b4hwu1 ,
drose-b4hwu2 ,
drose-b4hxs9 ,
drose-b4hxu4 ,
drose-b4hxz1 ,
drose-b4hyp8 ,
drose-b4hyp9 ,
drose-b4hyq0 ,
drose-b4hyz4 ,
drose-b4hyz5 ,
drose-b4i1k8 ,
drose-b4i2f3 ,
drose-b4i2w5 ,
drose-b4i4u3 ,
drose-b4i4u7 ,
drose-b4i4u9 ,
drose-b4i4v0 ,
drose-b4i4v1 ,
drose-b4i4v4 ,
drose-b4i4v5 ,
drose-b4i4v6 ,
drose-b4i4v7 ,
drose-b4i4v8 ,
drose-b4i4w0 ,
drose-b4i7s6 ,
drose-b4i133 ,
drose-b4i857 ,
drose-b4iam7 ,
drose-b4iam9 ,
drose-b4iaq6 ,
drose-b4icf6 ,
drose-b4icf7 ,
drose-b4id80 ,
drose-b4ifc5 ,
drose-b4ihv9 ,
drose-b4iie9 ,
drose-b4ilj8 ,
drose-b4in13 ,
drose-b4inj9 ,
drosi-ACHE ,
drosi-aes04a ,
drosi-b4nsh8 ,
drosi-b4q3d7 ,
drosi-b4q4w5 ,
drosi-b4q4y7 ,
drosi-b4q6h6 ,
drosi-b4q7u2 ,
drosi-b4q7u3 ,
drosi-b4q9c6 ,
drosi-b4q9c7 ,
drosi-b4q9d3 ,
drosi-b4q9d4 ,
drosi-b4q9r0 ,
drosi-b4q9r1 ,
drosi-b4q9r3 ,
drosi-b4q9s2 ,
drosi-b4q9s3 ,
drosi-b4q429 ,
drosi-b4q530 ,
drosi-b4q734 ,
drosi-b4q782 ,
drosi-b4q783 ,
drosi-b4q942 ,
drosi-b4qet1 ,
drosi-b4qfv6 ,
drosi-b4qge5 ,
drosi-b4qgh5 ,
drosi-b4qgs5 ,
drosi-b4qhf3 ,
drosi-b4qhf4 ,
drosi-b4qhi5 ,
drosi-b4qjr2 ,
drosi-b4qjr3 ,
drosi-b4qjv6 ,
drosi-b4qk23 ,
drosi-b4qk51 ,
drosi-b4qlt1 ,
drosi-b4qlz9 ,
drosi-b4qmn9 ,
drosi-b4qrq7 ,
drosi-b4qs01 ,
drosi-b4qs57 ,
drosi-b4qs82 ,
drosi-b4qs83 ,
drosi-b4qs84 ,
drosi-b4qs85 ,
drosi-b4qs86 ,
drosi-b4qsq1 ,
drosi-b4quk6 ,
drosi-b4qvg5 ,
drosi-b4qvg6 ,
drosi-b4qzn2 ,
drosi-b4qzn3 ,
drosi-b4qzn5 ,
drosi-b4qzn7 ,
drosi-b4qzn8 ,
drosi-b4qzp2 ,
drosi-b4qzp3 ,
drosi-b4qzp4 ,
drosi-b4qzp5 ,
drosi-b4qzp6 ,
drosi-b4qzp7 ,
drosi-b4r1a4 ,
drosi-b4r025 ,
drosi-b4r207 ,
drosi-b4r662 ,
drosi-este6 ,
drosi-q670k8 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lf33 ,
drovi-b4lf51 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgc6 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgk5 ,
drovi-b4lgn2 ,
drovi-b4lh17 ,
drovi-b4lh18 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4llm5 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lnr4 ,
drovi-b4lp47 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lqc6 ,
drovi-b4lr00 ,
drovi-b4lrp6 ,
drovi-b4lrw2 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lsq5 ,
drovi-b4lt32 ,
drovi-b4ltr1 ,
drovi-b4lui7 ,
drovi-b4lui9 ,
drovi-b4luj8 ,
drovi-b4luk0 ,
drovi-b4luk3 ,
drovi-b4luk8 ,
drovi-b4luk9 ,
drovi-b4lul0 ,
drovi-b4lve2 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4lyq2 ,
drovi-b4lyq3 ,
drovi-b4lz07 ,
drovi-b4lz13 ,
drovi-b4lz14 ,
drovi-b4lz15 ,
drovi-b4m0j7 ,
drovi-b4m0s0 ,
drovi-b4m2b6 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m6b9 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m564 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mb87 ,
drovi-b4mc71 ,
drovi-b4mfa4 ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mkt7 ,
drowi-b4mlc1 ,
drowi-b4mp68 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrd1 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4muj8 ,
drowi-b4mv18 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwp2 ,
drowi-b4mwp6 ,
drowi-b4mwq5 ,
drowi-b4mwr0 ,
drowi-b4mwr8 ,
drowi-b4mwr9 ,
drowi-b4mwt1 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myg1 ,
drowi-b4myh5 ,
drowi-b4n0d4 ,
drowi-b4n1a7 ,
drowi-b4n1c8 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n4x9 ,
drowi-b4n4y0 ,
drowi-b4n6m1 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4nae3 ,
drowi-b4ner8 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4nhz9 ,
drowi-b4nj18 ,
drowi-b4nj19 ,
drowi-b4nja7 ,
drowi-b4nja8 ,
drowi-b4nja9 ,
drowi-b4njk8 ,
drowi-b4nkc8 ,
drowi-b4nky0 ,
drowi-b4nl36 ,
drowi-b4nm27 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-ACHE ,
droya-aes04 ,
droya-b4itg2 ,
droya-b4itg6 ,
droya-b4itu9 ,
droya-b4iuv4 ,
droya-b4iuv5 ,
droya-b4nxe6 ,
droya-b4nxg5 ,
droya-b4nxg6 ,
droya-b4nxg8 ,
droya-b4nxw4 ,
droya-b4ny57 ,
droya-b4ny58 ,
droya-b4ny86 ,
droya-b4nzz8 ,
droya-b4p0b5 ,
droya-b4p0q9 ,
droya-b4p0r0 ,
droya-b4p0r7 ,
droya-b4p0r8 ,
droya-b4p0r9 ,
droya-b4p0s0 ,
droya-b4p0s2 ,
droya-b4p0t0 ,
droya-b4p0t1 ,
droya-b4p3h4 ,
droya-b4p3x8 ,
droya-b4p5g8 ,
droya-b4p6c9 ,
droya-b4p6l9 ,
droya-b4p6r1 ,
droya-b4p6r2 ,
droya-b4p7u4 ,
droya-b4p8w7 ,
droya-b4p023 ,
droya-b4p241 ,
droya-b4p774 ,
droya-b4pat9 ,
droya-b4pbl1 ,
droya-b4pd22 ,
droya-b4pd70 ,
droya-b4pdm8 ,
droya-b4pet9 ,
droya-b4pff9 ,
droya-b4pga7 ,
droya-b4pgu0 ,
droya-b4pig3 ,
droya-b4pjt8 ,
droya-b4pka2 ,
droya-b4plh2 ,
droya-b4pma3 ,
droya-b4pmv3 ,
droya-b4pmv4 ,
droya-b4pmv5 ,
droya-b4pn92 ,
droya-b4pp65 ,
droya-b4ppc5 ,
droya-b4ppc6 ,
droya-b4ppc7 ,
droya-b4ppc8 ,
droya-b4pq03 ,
droya-b4prg6B ,
droya-b4prg9 ,
droya-b4prh3 ,
droya-b4prh4 ,
droya-b4prh6 ,
droya-b4prh7 ,
droya-b4psz8 ,
droya-b4psz9 ,
droya-b4pv22 ,
droya-b4q0g5 ,
droya-b4q246 ,
droya-EST6 ,
droya-q71d76 ,
drowi-b4n7m9 ,
drope-b4gkk1 ,
droer-b3n5s3 ,
drose-b4i1w5 ,
drowi-a0a0q9x0t3 ,
drogr-b4jvm7 ,
dromo-b4ku70 ,
drovi-b4mcn9 ,
drovi-b4lty2 ,
drogr-b4jdu1 ,
drovi-a0a0q9wiq8 ,
dromo-b4kf70 ,
drosi-b2zi86 ,
droya-b4p2y4 ,
drose-b2zic5 ,
droer-b3n895 Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
Title: An evolutionary analysis of orphan genes in DrosophilaDomazet-Loso T , Tautz D Ref: Genome Res, 13 :2213, 2003 : PubMed Abstract ESTHER: Domazet-Loso_2003_Genome.Res_13_2213 PubMedSearch: Domazet-Loso 2003 Genome.Res 13 2213 PubMedID: 14525923 Gene_locus related to this paper: droya-b4p7u4 ,
droya-q71d76 Abstract
Orphan genes are protein-coding regions that have no recognizable homolog in distantly related species. A substantial fraction of coding regions in any genome sequenced consists of orphan genes, but the evolutionary and functional significance of orphan genes is not understood. We present a reanalysis of the Drosophila melanogaster proteome that shows that there are still between 26% and 29% of all proteins without a significant match with noninsect sequences, and that these orphans are underrepresented in genetic screens. To analyze the characteristics of orphan genes in Drosophila, we used sequence comparisons between cDNAs retrieved from two Drosophila yakuba libraries and their corresponding D. melanogaster orthologs. We find that a cDNA library from adults yields twice as many orphan genes as such a library from embryos. The orphan genes evolve on average more than three times faster than nonorphan genes, although the width of the evolutionary rate distribution is similar for the two classes. In particular, some orphan genes show very low substitution rates that are comparable to otherwise highly conserved genes. We propose a model suggesting that orphans may be involved in the evolution of adaptive traits, and that slow-evolving orphan genes may be particularly interesting candidate genes for identifying lineage-specific adaptations.
Title: Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genomeBergman CM , Pfeiffer BD , Rincon-Limas DE , Hoskins RA , Gnirke A , Mungall CJ , Wang AM , Kronmiller B , Pacleb J and Celniker SE <7 more author(s)> Bergman CM , Pfeiffer BD , Rincon-Limas DE , Hoskins RA , Gnirke A , Mungall CJ , Wang AM , Kronmiller B , Pacleb J , Park S , Stapleton M , Wan K , George RA , de Jong PJ , Botas J , Rubin GM , Celniker SE (- 7) Ref: Genome Biol, 3 :RESEARCH0086, 2002 : PubMed Abstract ESTHER: Bergman_2002_Genome.Biol_3_RESEARCH0086 PubMedSearch: Bergman 2002 Genome.Biol 3 RESEARCH0086 PubMedID: 12537575 Gene_locus related to this paper: drops-CG4390 ,
drowi-b4ngb5 ,
droya-q71d76 Abstract
BACKGROUND: It is widely accepted that comparative sequence data can aid the functional annotation of genome sequences; however, the most informative species and features of genome evolution for comparison remain to be determined.
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