Culex pipiens (House mosquito) Culex pipiens pipiens (Northern house mosquito) Culex quinquefasciatus (Southern house mosquito) (Culex pungens) Culex pipiens complex sp. Culex pipiens pallens Est-3 (coding esterase A)
Two esterase loci on chromosome alpha, Est-3 (coding esterase A) and Est-2 (coding esterase B), are amplified, expressing a higher amount of esterases and providing a substantial level of OP resistance. These two loci are tightly linked, and are always in complete linkage disequilibrium when amplified, thus they are referred to as the Ester superlocus. To date, 11 alleles conferring OP resistance have been identified at the Ester locus (the corresponding overproduced esterases are named in parentheses): Ester1(A1), Ester2(A2-B2), Ester4(A4-B4), Ester5(A5-B5), Ester8(A8-B8), Ester9(A9-B9), EsterB1(B1), EsterB6(B6), EsterB7(B7) EsterB7(B7), EsterB10(B10), Ester11(A11-B11) Other strains: Culex pipiens (House mosquito) Culex pipiens pipiens (Northern house mosquito) Culex quinquefasciatus (Southern house mosquito) (Culex pungens) Culex pipiens complex sp. Culex pipiens pallens
MDVEHPVVRT QYGPVRGVRK LAATGVDYYS FQRIPYVQPP VGEWRFKDAQ PPKPWTEPLD CTVQGPGGYQ YSKLLNKIIG SEDSLHMNVF TKNLDSKQLL PVMLYIHGGA FMRGSSGVEM YGPDYLIQKD VVFVSFNYRI GALGFISFDS PELGLPGNAG LKDQNLALRW VVDNVANFGG DPKNITLFGE SAGGCSVHYH MVSDLSRGLF QRAIVMSGCV LNNWSVVPRR KFSERLAKAL GWNGQGGERA ALEVLVKADP ERIVREQEVL LNENEIENRI LFSFGPVIEP YITKNCMIPK DPVEMCREAW SNEIDILIGG NSEEGLFCLN GIKENPSIMS NLKDFEYLVP LELDLIRTSQ RCKEVGKQMK KFYYGETEPS FENREGYLTL MTDKLFLHGL HRTILSRLNS KKPSKTFLYR FSVDSDTYNH YRIVFCDKNV RGTAHADDLS YIFKNVFNDP PAKDTFEHRA MMNMVGLFST FASNNGNPNG EQTNEWESIA TPAGPFKCLN INNDGLQFIE YPEQERMKFW DSLYSKDKLI
| Title : Insecticide resistance alleles in wetland and residential populations of the West Nile virus vector Culex pipiens in New Jersey - Johnson_2016_Pest.Manag.Sci_72_481 |
| Author(s) : Johnson BJ , Fonseca DM |
| Ref : Pest Manag Sci , 72 :481 , 2016 |
| Abstract : Johnson_2016_Pest.Manag.Sci_72_481 |
| ESTHER : Johnson_2016_Pest.Manag.Sci_72_481 |
| PubMedSearch : Johnson_2016_Pest.Manag.Sci_72_481 |
| PubMedID: 25809655 |
| Gene_locus related to this paper: culpi-ESTA |
| Title : Identification of resistant carboxylesterase alleles in Culex pipiens complex via PCR-RFLP - Zhang_2012_Parasit.Vectors_5_209 |
| Author(s) : Zhang H , Meng F , Qiao C , Cui F |
| Ref : Parasit Vectors , 5 :209 , 2012 |
| Abstract : Zhang_2012_Parasit.Vectors_5_209 |
| ESTHER : Zhang_2012_Parasit.Vectors_5_209 |
| PubMedSearch : Zhang_2012_Parasit.Vectors_5_209 |
| PubMedID: 23006470 |
| Gene_locus related to this paper: culpi-ESTA |
| Title : Characterization of novel esterases in insecticide-resistant mosquitoes - Cui_2007_Insect.Biochem.Mol.Biol_37_1131 |
| Author(s) : Cui F , Weill M , Berthomieu A , Raymond M , Qiao CL |
| Ref : Insect Biochemistry & Molecular Biology , 37 :1131 , 2007 |
| Abstract : Cui_2007_Insect.Biochem.Mol.Biol_37_1131 |
| ESTHER : Cui_2007_Insect.Biochem.Mol.Biol_37_1131 |
| PubMedSearch : Cui_2007_Insect.Biochem.Mol.Biol_37_1131 |
| PubMedID: 17916499 |
| Gene_locus related to this paper: culpi-ESTA , culqu-1estb |
| Title : Molecular comparisons of the Culex pipiens (L.) complex esterase gene amplicons - Buss_2004_Insect.Biochem.Mol.Biol_34_433 |
| Author(s) : Buss DS , Callaghan A |
| Ref : Insect Biochemistry & Molecular Biology , 34 :433 , 2004 |
| Abstract : Buss_2004_Insect.Biochem.Mol.Biol_34_433 |
| ESTHER : Buss_2004_Insect.Biochem.Mol.Biol_34_433 |
| PubMedSearch : Buss_2004_Insect.Biochem.Mol.Biol_34_433 |
| PubMedID: 15110864 |
| Gene_locus related to this paper: culpi-1este , culpi-ESTA |
| Title : Co-amplification explains linkage disequilibrium of two mosquito esterase genes in insecticide-resistant Culex quinquefasciatus - Vaughan_1997_Biochem.J_325 ( Pt 2)_359 |
| Author(s) : Vaughan A , Hawkes N , Hemingway J |
| Ref : Biochemical Journal , 325 ( Pt 2) :359 , 1997 |
| Abstract : Vaughan_1997_Biochem.J_325 ( Pt 2)_359 |
| ESTHER : Vaughan_1997_Biochem.J_325 ( Pt 2)_359 |
| PubMedSearch : Vaughan_1997_Biochem.J_325 ( Pt 2)_359 |
| PubMedID: 9230114 |
| Gene_locus related to this paper: culpi-ESTA |
| Title : Coamplification of esterase A and B genes as a single unit in Culex pipiens misquitos - Rooker_1996_Heredity_77_555 |
| Author(s) : Rooker S , Guillema T , Berge JB , Pasteur N , Raymond M |
| Ref : Heredity , 77 (5) :555 , 1996 |
| Abstract : Rooker_1996_Heredity_77_555 |
| ESTHER : Rooker_1996_Heredity_77_555 |
| PubMedSearch : Rooker_1996_Heredity_77_555 |
| PubMedID: 8939022 |
| Gene_locus related to this paper: culpi-ESTA |
| Title : Mosquito carboxylesterase Est alpha 2(1) (A2). Cloning and sequence of the full-length cDNA for a major insecticide resistance gene worldwide in the mosquito Culex quinquefasciatus - Vaughan_1995_J.Biol.Chem_270_17044 |
| Author(s) : Vaughan A , Hemingway J |
| Ref : Journal of Biological Chemistry , 270 :17044 , 1995 |
| Abstract : Vaughan_1995_J.Biol.Chem_270_17044 |
| ESTHER : Vaughan_1995_J.Biol.Chem_270_17044 |
| PubMedSearch : Vaughan_1995_J.Biol.Chem_270_17044 |
| PubMedID: 7622525 |
| Gene_locus related to this paper: culpi-ESTA |