clacd-cla3

Cladosporium cladosporioides. Cladosporin biosynthesis cluster protein 3

Comment

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Cladosporium cladosporioides

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

KPGSTIATTS PVLESGKSEQ GMFQALIAAI VKTTGGELSE LNDDTELADI GVDSIMAIEI VAHVKDATNQ DLPLSFVLEY PTIGNLRCAF DEDVSSEFTD SEVTSGTPNS SESVTSEEEL PGPEEHAFKE PKDDSPLARR DMDNSNDRSL DGGVLDDGSP QPRVRISLLQ GRPVRGKPKF FLIADGSGSI ATYIHLPPAK VKMPIYGVDS PFLHCPSRFT PEAGIPAAAK WIVEALMKAQ PEGPFFLGGF SGGAMLSYEV ARQLAAFDRK VDSMVLIDMC CPRPAVSSDL KESLWNDDIE SFEEIASHVG SNVASNMQQH LRAIFKAVSV YHPPSMTAKE RPDRTIIIWA KKGMITRCHD VPEIMERLSA RGLTRTIPEG FMEDPSFGAI RWSFVSKGAN DLGPNGWQKY IGHEPLCLSV DLDHLEMMEP GQVHIFRGAF EEAFRLIEA

References

Title : Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent - Cochrane_2016_Angew.Chem.Int.Ed.Engl_55_664
Author(s) : Cochrane RV , Sanichar R , Lambkin GR , Reiz B , Xu W , Tang Y , Vederas JC
Ref : Angew Chem Int Ed Engl , 55 :664 , 2016
Abstract : Cochrane_2016_Angew.Chem.Int.Ed.Engl_55_664
ESTHER : Cochrane_2016_Angew.Chem.Int.Ed.Engl_55_664
PubMedSearch : Cochrane_2016_Angew.Chem.Int.Ed.Engl_55_664
PubMedID: 26783060
Gene_locus related to this paper: clacd-cla3

Title : Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor - Fang_2015_Chem.Biol_22_734
Author(s) : Fang P , Han H , Wang J , Chen K , Chen X , Guo M
Ref : Chemical Biology , 22 :734 , 2015
Abstract : Fang_2015_Chem.Biol_22_734
ESTHER : Fang_2015_Chem.Biol_22_734
PubMedSearch : Fang_2015_Chem.Biol_22_734
PubMedID: 26074468
Gene_locus related to this paper: clacd-cla3

Title : Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin - Khan_2014_J.Struct.Funct.Genomics_15_63
Author(s) : Khan S , Sharma A , Belrhali H , Yogavel M
Ref : J Struct Funct Genomics , 15 :63 , 2014
Abstract : Khan_2014_J.Struct.Funct.Genomics_15_63
ESTHER : Khan_2014_J.Struct.Funct.Genomics_15_63
PubMedSearch : Khan_2014_J.Struct.Funct.Genomics_15_63
PubMedID: 24935905
Gene_locus related to this paper: clacd-cla3

Title : Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin - Hoepfner_2012_Cell.Host.Microbe_11_654
Author(s) : Hoepfner D , McNamara CW , Lim CS , Studer C , Riedl R , Aust T , McCormack SL , Plouffe DM , Meister S , Schuierer S , Plikat U , Hartmann N , Staedtler F , Cotesta S , Schmitt EK , Petersen F , Supek F , Glynne RJ , Tallarico JA , Porter JA , Fishman MC , Bodenreider C , Diagana TT , Movva NR , Winzeler EA
Ref : Cell Host Microbe , 11 :654 , 2012
Abstract : Hoepfner_2012_Cell.Host.Microbe_11_654
ESTHER : Hoepfner_2012_Cell.Host.Microbe_11_654
PubMedSearch : Hoepfner_2012_Cell.Host.Microbe_11_654
PubMedID: 22704625
Gene_locus related to this paper: clacd-cla3

Title : Cladosporin, a new antifungal metabolite from Cladosporium cladosporioides -
Author(s) : Scott PM , Van Walbeek W , MacLean WM
Ref : J Antibiot (Tokyo) , 24 :747 , 1971
PubMedID: 5169000
Gene_locus related to this paper: clacd-cla3