(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Eukaryota: NE > Opisthokonta: NE > Metazoa: NE > Eumetazoa: NE > Bilateria: NE > Deuterostomia: NE > Chordata: NE > Craniata: NE > Vertebrata: NE > Gnathostomata: NE > Teleostomi: NE > Euteleostomi: NE > Sarcopterygii: NE > Dipnotetrapodomorpha: NE > Tetrapoda: NE > Amniota: NE > Sauropsida: NE > Sauria: NE > Archelosauria: NE > Archosauria: NE > Dinosauria: NE > Saurischia: NE > Theropoda: NE > Coelurosauria: NE > Aves: NE > Neognathae: NE > Galloanserae: NE > Galliformes: NE > Phasianidae: NE > Phasianinae: NE > Gallus: NE > Gallus gallus: NE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MAPLFLLLLLLLSPSPTSAHRFAYSAPNRPEVRTTTGSVRGLLIPAGPSG STAAAFLGIPFAVPPLGPLRFRPPLPIPTPWTGIRDADSQPFACYQMVDT TFPGFQGSEMWNPNREMSEDCLYLNVWTQKGDPTEPPVLVWIYGGGFTGG SVSLDVYDGRYLAAAEEAVVVSMNYRVGSLGFLALAGHRDAPGNVGLWDQ RLALQWVRDNAEAFGGDPDLITLFGESAGAASVGFHLLSPHSKGLFRRAV LQSGSPNGPWATIGAAEGRRRAAALGRAVGCPYGNETEFLGCLRGKEAAD VLEGEGVVMPPQSVFRFAFVPVVDGDFVVDSPDVALWGDYGVKGGEGGHG VEGGDGGYGVKGGDGVKGGYGGGYGARGVREGDGDGGYGVKEGLREGYGV KEGYGVEGDGANAYGARVPPRPHRDETPPDAYGAKGSADAYGAKAAPRPH RDETSPDAYGAKMPPRPHRDEASPDTYGAKMPPRPHRDETSPDAYGAKMP PRPHRAGGEVEVLLGAVRVEGSYFLVYGVPGFGKDNESLISREEFLGGVR MGVPQATELAAEAVVLHYTDWLDADNPVKNREALDDIVGDHNVVCPLMAF AQRWAQRGGKVYAYLFDHRSSTLLWPSWMGVPHGYEIEFVFGLPLEPRNN YTREEVELSRRIMRYWGNFARTGDPNGGVGGPRWPPYTPSGQRYAHLNAR PLSVGHGLRTQICAFWTRFLPKLLNATGPPEDAEREWRLEFHRWSSYMGR WRTQFEHYSRQQPCATL
Reference
Title: Cloning and analysis of chicken acetylcholinesterase transcripts from muscle and brain Randall WR, Rimer M, Gough NR Ref: Biochimica & Biophysica Acta, 1218:453, 1994 : PubMed
We have isolated cDNA clones from an embryonic chicken muscle cDNA library which encodes the complete catalytic T subunit of acetylcholinesterase. The deduced polypeptide comprises 767 amino acids, shows approximately 60% homology to acetylcholinesterases from other vertebrates and contains a 155 amino acid sequence inserted into the middle of the peptide which is unique to the chicken enzyme. Northern blots of embryonic chicken muscle and adult brain show three transcripts approximately 4.5, 5.5, and 6.0 kb hybridizing to a cDNA fragment of AChE. The 6.0 kb transcript is expressed transiently in embryonic muscle and is a major transcript in adult brain.
