Gene_locus Report for: bovin-f1n385

Other strains: Bos taurus (Bovine); Bos mutus (wild yak)

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Laurasiatheria: N E > Cetartiodactyla: N E > Ruminantia: N E > Pecora: N E > Bovidae: N E > Bovinae: N E > Bos: N E > Bos taurus: N E

A85-EsteraseD-FGH : bovin-estdBos taurus (Bovine) Esterase D.
ABHD6-Lip : bovin-q1lz86Bos taurus (Bovine) similar to abhydrolase domain containing 6.
ABHD8 : bovin-abhd8Bos taurus (Bovine); Bos mutus (wild yak) abhydrolase domain-containing protein 8 (EC 3.-.-.-).
ABHD10 : bovin-ABHDABos taurus (Bovine); Bos mutus (wild yak) abhydrolase domain containing 10.
ABHD11-Acetyl_transferase : bovin-q3sz73Bos taurus (Bovine) abhydrolase domain containing 11.
ABHD12-PHARC : bovin-f1mps6Bos taurus (Bovine) Uncharacterized protein, bovin-q08dw9Bos taurus (Bovine), Bos mutus (wild Yak) abhydrolase domain containing protein 12.
ABHD13-BEM46 : bovin-a7mb66Bos taurus (Bovine). Abhydrolase domain containing 13.
ABHD16 : bovin-ABHD16ABos taurus (Bovine) Phosphatidylserine lipase ABHD16A HLA-B-associated transcript 5 BAT5, bovin-ABHD16BBos taurus (Bovine); Bos mutus (wild yak) Abhydrolase domain containing 16B.
ABHD17-depalmitoylase : bovin-AB17ABos taurus (Bovine) Abhydrolase domain-containing protein FAM108A, bovin-AB17CBos taurus (Bovine) Abhydrolase domain-containing protein FAM108C1.
ABHD18 : bovin-f1n673Bos taurus (Bovine). Uncharacterized protein.
abh_upf0017 : bovin-abhd1Bos taurus (Bovine) lung alpha/beta hydrolase 1 (Labh1-pending) hypothetical protein mgc127615, bovin-abhd2Bos taurus (Bovine) alpha/beta hydrolase domain containing protein 2, bovin-abhd3Bos taurus (Bovine) Abhydrolase domain-containing protein 3, bovin-e1bkm2Bos taurus (Bovine) Abhydrolase domain containing 15.
ACHE : bovin-ACHEBos taurus protein for acetylcholinesterase T subunit.
Acidic_Lipase : bovin-1lipgBos taurus (Bovine) Gastric triacylglycerol lipase, bovin-e1ba50Bos taurus (Bovine) Lipase, bovin-e1bnt1Bos taurus (Bovine) Lipase LIPJ, bovin-f1msa3Bos taurus (Bovine) Lipase LIPK, bovin-f1n110Bos taurus (Bovine) Lipase.
ACPH_Peptidase_S9 : bovin-acphBos taurus (Bovine) Acylaminoacyl-peptidase.
Arb2_FAM172A : bovin-a0a3q1nm09Bos taurus (Bovine); Bos mutus (wild yak). Uncharacterized protein.
Arylacetamide_deacetylase : bovin-aaadBos taurus (Bovine); Bos mutus (Bovine, wild yak) Arylacetamide deacetylase, bovin-nceh1Bos taurus (Bovine); Bos mutus Arylacetamide deacetylase-like 1, bovin-g5e5g5Bos taurus (Bovine). Uncharacterized protein, bovin-g5e5i3Bos taurus (Bovine). Uncharacterized protein.
BCHE : bovin-BCHEBos taurus (Bovine), Bos mutus (wild yak) butyrylcholinesterase.
Carboxypeptidase_S10 : bovin-ppgbBos taurus (Bovine) Lysosomal protective protein Cathepsin A Peptidase_S10 mgc128937, bovin-q2nkz9Bos taurus (Bovine) similar to serine carboxypeptidase 1 protein.
Carb_B_Chordata : bovin-e1bn79Bos taurus (Bovine) Bos mutus (Yak) cauxin, bovin-est8Bos taurus (Bovine) Bos mutus (Yak) Carboxylesterase 4A (Carboxylesterase 8) UNQ440/PRO873 homolog, bovin-f1mi11Bos taurus (Bovine) Bos mutus (Yak) Uncharacterized protein, bovin-q2kj30Bos taurus (Bovine), Bos mutus (Yak) hypothetical protein, bovin-q3t0r6Bos taurus (Bovine), Bos mutus (Yak) hypothetical protein mgc127393, bovin-q5myb8Bos taurus (Bovine) retinyl ester hydrolase type 1 breh1.
CGI-58_ABHD5_ABHD4 : bovin-abhd4Bos taurus (Bovine) abhydrolase domain containing protein 4 Lyso-N-acylphosphatidylethanolamine lipase, bovin-q0vcc8Bos taurus (Bovine) Abhydrolase domain containing 5.
Cholesterol_esterase : bovin-balip Bos taurus (Bovine) Bos mutus (Yak) protein for bile-salt-activated lipase.
CIB-CCG1-interacting-factor-B : bovin-abhebBos taurus (Bovine) Abhydrolase domain-containing protein 14B, bovin-f1mr65Bos taurus (Bovine) Uncharacterized protein.
CMBL : bovin-f1n2i5Bos taurus (Bovine); Bos indicus x Bos taurus (Hybrid cattle); Bos mutus (wild yak). Carboxymethylenebutenolidase homolog.
DPP4N_Peptidase_S9 : bovin-a0jnh8Bos taurus (Bovine) Dipeptidyl-peptidase 10, bovin-a5d7b7Bos taurus (Bovine) Uncharacterized protein, bovin-dpp4Bos taurus (Bovine) dipeptidyl peptidase IV, bovin-dpp6Bos taurus (Bovine) related protein) (dipeptidylpeptidase VI) (dppx), bovin-e1bi31Bos taurus (Bovine) Uncharacterized protein, bovin-f1n1l4Bos taurus (Bovine) Uncharacterized protein.
Duf_676 : bovin-e1bpw3Bos taurus (Bovine) Uncharacterized protein, bovin-f1mcd9Bos taurus (Bovine) Uncharacterized protein.
Duf_829 : bovin-tmm53Bos taurus (Bovine) Transmembrane protein 53.
Epoxide_hydrolase : bovin-q3zcj6Bos taurus (Bovine) hypothetical protein mgc126963.
FSH1 : bovin-OVCA2Bos taurus (Bovine); Bos mutus (wild yak) hypothetical protein mgc128661.
Hepatic_Lipase : bovin-q3sz79Bos taurus (Bovine); Bos mutus grunniens (Wild yak) (Bos grunniens) lipase, hepatic.
Hormone-sensitive_lipase_like : bovin-hslipBos taurus (Bovine) 17.6 kda hormone-sensitive lipase (fragment).
Kynurenine-formamidase : bovin-e1bll5Bos taurus (Bovine). N-formylkynurenine formamidase.
Lipase_3 : bovin-e1bbv2Bos taurus (Bovine); Bos mutus (wild yak) Uncharacterized protein.
Lipoprotein_Lipase : bovin-lipli Bos taurus; Bos mutus grunniens (Wild yak) (Bos grunniens); Bubalus bubalis (Domestic water buffalo) lipoprotein lipase, bovin-LIPGBos taurus; Bos mutus (wild yak) lipase G, endothelial type (LIPG).
LYsophospholipase_carboxylesterase : bovin-lypa1Bos taurus (Bovine) lysophospholipase I.
Maspardin-ACP33-SPG21_like : bovin-SPG21Bos taurus (Bovine); Bos mutus (wild Yak) hypothetical protein acid cluster protein 33 ACP33 SPG21 maspardin.
MEST-like : bovin-q2hjm9Bos taurus (Bovine) mesoderm-specific transcript Paternally-expressed gene 1 peg1 (fragment).
Ndr_family : bovin-ndr1Bos taurus (Bovine) hypothetical protein mgc127533, bovin-ndrg2Bos taurus (Bovine) mgc128884 Protein NDRG2, bovin-ndrg3Bos taurus (Bovine) Protein NDRG3, bovin-q0vck8Bos taurus (Bovine) Uncharacterized protein.
Neuroligin : bovin-2neurBos taurus (Bovine), Bos mutus (Wild Yak) NLGN2 Neuroligin 2, bovin-3neurBos taurus (Bovine) similar to neuroligin 3, bovin-g3mxp5Bos taurus (Bovine) Bos mutus (Yak) Neuroligin-3.
NLS3-Tex30 : bovin-KANSL3Bos taurus (Bovine) Bos Mutus (Yak) LOC618190 protein, bovin-TEX30Bos taurus (Bovine), Bos mutus (Yak) Testis-expressed sequence 30 protein, C13orf27 homolog.
PAF-Acetylhydrolase : bovin-paf2Bos taurus (Bovine) (EC 3.1.1.47) (serine dependent phospholipase a2), bovin-pafaBovine plasma PAF acetylhydrolase.
Palmitoyl-protein_thioesterase : bovin-ppt Bos taurus palmitoyl-protein thioesterase mRNA, complete cds, bovin-ppt2Bos taurus (Bovine) Lysosomal thioesterase PPT2.
Pancreatic_lipase : bovin-lipr2Bos taurus (Bovine); Bos mutus (wild yak) Pancreatic lipase-related protein 2 Can hydrolyze both phospholipids and galactolipids, bovin-e1bjq9Bos taurus (Bovine); Bos mutus (wild yak). Pancreatic lipase, bovin-f1mc21Bos taurus (Bovine); Bos mutus (wild yak). Pancreatic lipase.
PC-sterol_acyltransferase : bovin-lcatBos taurus (Bovine) phosphatidylcholine-sterol acyltransferase, bovin-LPLA2Bos taurus (Bovine) lysosomal phospholipase a2 ( lysophospholipase 3).
Pectinacetylesterase-Notum : bovin-f1mbd6Bos taurus (Bovine) palmitoleoyl-protein carboxylesterase NOTUM.
PGAP1 : bovin-e1bnq0Bos taurus (Bovine) Uncharacterized protein, bovin-srac1Bos taurus (Bovine) Protein SERAC1.
Phospholipase : bovin-q5e9h0Bos taurus (Bovine) phospholipase a1 member a, bovin-f1mxa8Bos taurus (Bovine). Lipase H.
PPase_methylesterase_euk : bovin-ppme1Bos taurus (Bovine) protein phosphatase methylesterase-1.
Prolylcarboxypeptidase : bovin-a6qnx2Bos taurus (Bovine) DPP7 protein, bovin-q2ta14Bos taurus (Bovine) hypothetical protein.
S9N_PPCE_Peptidase_S9 : bovin-ppceBos taurus (Bovine) (PE).
Thioesterase : bovin-fasBos taurus (Bovine) oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14).
Thyroglobulin : bovin-thyro Bos taurus (Bovine) Thyroglobulin.
Valacyclovir-hydrolase : bovin-q2kix6Bos taurus (Bovine) Biphenyl hydrolase-like Serine hydrolase; breast epithelial mucin-associated antigen

Title: The yak genome and adaptation to life at high altitude
Qiu Q, Zhang G, Ma T, Qian W, Wang J, Ye Z, Cao C, Hu Q, Kim J and Liu J <35 more author(s)> Qiu Q, Zhang G, Ma T, Qian W, Wang J, Ye Z, Cao C, Hu Q, Kim J, Larkin DM, Auvil L, Capitanu B, Ma J, Lewin HA, Qian X, Lang Y, Zhou R, Wang L, Wang K, Xia J, Liao S, Pan S, Lu X, Hou H, Wang Y, Zang X, Yin Y, Ma H, Zhang J, Wang Z, Zhang Y, Zhang D, Yonezawa T, Hasegawa M, Zhong Y, Liu W, Huang Z, Zhang S, Long R, Yang H, Lenstra JA, Cooper DN, Wu Y, Shi P, Liu J (- 35)
Ref: Nat Genet, 44:946, 2012 : PubMed
Abstract


ESTHER: Qiu_2012_Nat.Genet_44_946
PubMedSearch: Qiu 2012 Nat.Genet 44 946
PubMedID: 22751099
Gene_locus related to this paper: bosmu-l8ic43, bovin-2neur, bovin-balip, bovin-BCHE, bovin-e1bbv2, bovin-e1bn79, bovin-est8, bovin-f1mi11, bovin-f1n385, bovin-g3mxp5, bovin-lipli, bovin-lipr2, bovin-q2kj30, bovin-q3sz79, bovin-q3t0r6, bovin-ABHDA, bovin-q08dw9, bovin-ABHD16B, bovin-SPG21, bovin-TEX30, 9ceta-l8iwv2, 9ceta-l8idy3, 9ceta-l8hsi3, bovin-e1bjq9, bovin-f1mc21, 9ceta-l8hyl8, bovin-LIPG, bovin-a0a3q1nm09, bovin-f1n2i5

Abstract

Domestic yaks (Bos grunniens) provide meat and other necessities for Tibetans living at high altitude on the Qinghai-Tibetan Plateau and in adjacent regions. Comparison between yak and the closely related low-altitude cattle (Bos taurus) is informative in studying animal adaptation to high altitude. Here, we present the draft genome sequence of a female domestic yak generated using Illumina-based technology at 65-fold coverage. Genomic comparisons between yak and cattle identify an expansion in yak of gene families related to sensory perception and energy metabolism, as well as an enrichment of protein domains involved in sensing the extracellular environment and hypoxic stress. Positively selected and rapidly evolving genes in the yak lineage are also found to be significantly enriched in functional categories and pathways related to hypoxia and nutrition metabolism. These findings may have important implications for understanding adaptation to high altitude in other animal species and for hypoxia-related diseases in humans.



        

Title: A whole-genome assembly of the domestic cow, Bos taurus
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP and Salzberg SL <5 more author(s)> Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marcais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL (- 5)
Ref: Genome Biol, 10:R42, 2009 : PubMed
Abstract


ESTHER: Zimin_2009_Genome.Biol_10_R42
PubMedSearch: Zimin 2009 Genome.Biol 10 R42
PubMedID: 19393038
Gene_locus related to this paper: bovin-1lipg, bovin-ABHD16A, bovin-e1ba50, bovin-e1bbv2, bovin-e1bkm2, bovin-e1bnq0, bovin-e1bnt1, bovin-e1bpw3, bovin-f1mcd9, bovin-f1mps6, bovin-f1msa3, bovin-f1n110, bovin-f1n385, bovin-hslip, bovin-KANSL3, bovin-ndrg2, bovin-q0vck8, bovin-q2kix6, bovin-q2ta14, bovin-q3sz73, bovin-q3sz79, bovin-f1n673, bovin-e1bll5, bovin-g5e5g5, bovin-g5e5i3, bovin-e1bjq9, bovin-f1mc21, bovin-a0a3q1nm09, bovin-a7mb66

Abstract

BACKGROUND: The genome of the domestic cow, Bos taurus, was sequenced using a mixture of hierarchical and whole-genome shotgun sequencing methods.
RESULTS: We have assembled the 35 million sequence reads and applied a variety of assembly improvement techniques, creating an assembly of 2.86 billion base pairs that has multiple improvements over previous assemblies: it is more complete, covering more of the genome; thousands of gaps have been closed; many erroneous inversions, deletions, and translocations have been corrected; and thousands of single-nucleotide errors have been corrected. Our evaluation using independent metrics demonstrates that the resulting assembly is substantially more accurate and complete than alternative versions.
CONCLUSIONS: By using independent mapping data and conserved synteny between the cow and human genomes, we were able to construct an assembly with excellent large-scale contiguity in which a large majority (approximately 91%) of the genome has been placed onto the 30 B. taurus chromosomes. We constructed a new cow-human synteny map that expands upon previous maps. We also identified for the first time a portion of the B. taurus Y chromosome.