aspte-curs2

Aspergillus terreus. Dehydrocurvularin biosynthesis protein 2. AtCURS2 Thioesterase domain

Comment

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Aspergillus terreus

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

PQPAEVGEDD DDDFDEGLVD AILDSISKAT GSDPSEFTDD TIVADLGVDS IMAIEVVATV KEQSGLDLPA TFVLEHPTIG DLRRAFGANK PKTSKPQPGS TTPSSSQSSI PSSPNPEPTS MSDTASSLGS SLVDIEKDQT FTPPPELEPK PNHHLGKMDE TDTSPAPTVR ITLLQGRPSP KRTPFYMMAD GTGTIATYIH LPAFKSKMPV YGIDSPFLRC PSRLTKDVGI PGVAKLIVDA LVTAQPTGPL MIGGFSAGSI VAYEVTRQLG ALGRQVTGLV LIDMCCPRSS LLDEDAMNSE DDASFAIFEN AVSKDGLWSL ASTTQDHFRA YHVAMHAYHP PYMTAQERPS HTAVIWAEKG MVNRVVGNDR LMQMLADQGI PTTSYPGYME DPRLGAFACL VPDRTAADLG PNGWEKYTAG EVLALSVAGD HLDLPMPGHV HLLQREMEKA FAYFEGEST

References

Title : Comparison of 10,11-Dehydrocurvularin Polyketide Synthases from Alternaria cinerariae and Aspergillus terreus Highlights Key Structural Motifs - Cochrane_2015_Chembiochem_16_2479
Author(s) : Cochrane RV , Gao Z , Lambkin GR , Xu W , Winter JM , Marcus SL , Tang Y , Vederas JC
Ref : Chembiochem , 16 :2479 , 2015
Abstract : Cochrane_2015_Chembiochem_16_2479
ESTHER : Cochrane_2015_Chembiochem_16_2479
PubMedSearch : Cochrane_2015_Chembiochem_16_2479
PubMedID: 26493380
Gene_locus related to this paper: aspte-curs2 , altci-dhc5

Title : Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus - Xu_2013_Appl.Environ.Microbiol_79_2038
Author(s) : Xu Y , Espinosa-Artiles P , Schubert V , Xu YM , Zhang W , Lin M , Gunatilaka AA , Sussmuth R , Molnar I
Ref : Applied Environmental Microbiology , 79 :2038 , 2013
Abstract : Xu_2013_Appl.Environ.Microbiol_79_2038
ESTHER : Xu_2013_Appl.Environ.Microbiol_79_2038
PubMedSearch : Xu_2013_Appl.Environ.Microbiol_79_2038
PubMedID: 23335766
Gene_locus related to this paper: aspte-curs2

Title : Rational reprogramming of fungal polyketide first-ring cyclization - Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
Author(s) : Xu Y , Zhou T , Zhou Z , Su S , Roberts SA , Montfort WR , Zeng J , Chen M , Zhang W , Lin M , Zhan J , Molnar I
Ref : Proc Natl Acad Sci U S A , 110 :5398 , 2013
Abstract : Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
ESTHER : Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
PubMedSearch : Xu_2013_Proc.Natl.Acad.Sci.U.S.A_110_5398
PubMedID: 23509261
Gene_locus related to this paper: aspte-curs2 , floch-rads2

Title : Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis - Xu_2013_J.Am.Chem.Soc_135_10783
Author(s) : Xu Y , Zhou T , Zhang S , Xuan LJ , Zhan J , Molnar I
Ref : Journal of the American Chemical Society , 135 :10783 , 2013
Abstract : Xu_2013_J.Am.Chem.Soc_135_10783
ESTHER : Xu_2013_J.Am.Chem.Soc_135_10783
PubMedSearch : Xu_2013_J.Am.Chem.Soc_135_10783
PubMedID: 23822773
Gene_locus related to this paper: aspte-curs2 , floch-rads2