Gene_Locus Report

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Gene_locus Report for: ascsu-u1mei8

Ascaris suum (Pig roundworm) (Ascaris lumbricoides) Acetylcholinesterase 4

Relationship
Family|ACHE
Block| C
Position in NCBI Life Tree|Ascaris suum
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Nematoda: N E > Chromadorea: N E > Ascaridida: N E > Ascaridoidea: N E > Ascarididae: N E > Ascaris: N E > Ascaris suum: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AEUI02000262, ERG82985
Sequence
Graphical view for this peptide sequence: ascsu-u1mei8
Colored MSA for ACHE (raw)
MFPYSLLKLQQAWGATTKIGCGVANCTDPPWYVTHVDCMGISSHEEHIPI
ELQLRLGTIRGFESIFLHKRVRSFLGVPFAEPPIGRNRFRPPLPKRSWNG
TIDATQLSPACYQARDTYNETFWGSEMWNANTPNKEDCLYVNIWTPAEAN
NLTVMVWLFGGGYYYGSPSLILYDGKALALTANVIVININYRVGPFGYLY
FDHEDAPGNMGMLDQQLALHWIRENVHSFGGNPAHIALFGESAGAASIVA
HLVAPASRGLFNNGILQSGTLDNKWSLDSPTRALQKSEALAKRHNCFKED
VRETLSCLRALPAAKLLEGMWLNLEFLEFPFVPVSRDRNFFRQYDGFIAL
HSGQFNKNVNIMVGINHDEGNFWNIYNMPEYFDKSEQPLLSQEDFLKCVN
TAFKTQPEVVRDAAAFVYLDKKCEHGLAKNKYYAEQVNQMVGDYFFTCDS
LWLAEQMKGAEGKVYVYYFDQPSSANPWPKWTGVMHAYEIEYVFGVPIYN
ITAGYTNREKIFSQKIIQYWRNFAAEGVPHLNDNYGEPWPEYHKSNQWMY
LRGGSHIKPIERRKQRECAMWRSAKEIEYYKYLRQLRTTSASAIYSYSLV
YFMLLFLLIVRFRRS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MFPYSLLKLQQAWGATTKIGCGVANCTDPPWYVTHVDCMGISSHEEHIPI
ELQLRLGTIRGFESIFLHKRVRSFLGVPFAEPPIGRNRFRPPLPKRSWNG
TIDATQLSPACYQARDTYNETFWGSEMWNANTPNKEDCLYVNIWTPAEAN
NLTVMVWLFGGGYYYGSPSLILYDGKALALTANVIVININYRVGPFGYLY
FDHEDAPGNMGMLDQQLALHWIRENVHSFGGNPAHIALFGESAGAASIVA
HLVAPASRGLFNNGILQSGTLDNKWSLDSPTRALQKSEALAKRHNCFKED
VRETLSCLRALPAAKLLEGMWLNLEFLEFPFVPVSRDRNFFRQYDGFIAL
HSGQFNKNVNIMVGINHDEGNFWNIYNMPEYFDKSEQPLLSQEDFLKCVN
TAFKTQPEVVRDAAAFVYLDKKCEHGLAKNKYYAEQVNQMVGDYFFTCDS
LWLAEQMKGAEGKVYVYYFDQPSSANPWPKWTGVMHAYEIEYVFGVPIYN
ITAGYTNREKIFSQKIIQYWRNFAAEGVPHLNDNYGEPWPEYHKSNQWMY
LRGGSHIKPIERRKQRECAMWRSAKEIEYYKYLRQLRTTSASAIYSYSLV
YFMLLFLLIVRFRRS


References
    Title: Silencing of germline-expressed genes by DNA elimination in somatic cells
    Wang J, Mitreva M, Berriman M, Thorne A, Magrini V, Koutsovoulos G, Kumar S, Blaxter ML, Davis RE
    Ref: Dev Cell, 23:1072, 2012 : PubMed

            

    Title: Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles
    Wang J, Czech B, Crunk A, Wallace A, Mitreva M, Hannon GJ, Davis RE
    Ref: Genome Res, 21:1462, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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