Gene_Locus Report

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Gene_locus Report for: ascsu-f1l1m9

Ascaris suum (Pig roundworm) (Ascaris lumbricoides) Esterase

Comment
Giant roundworm


Relationship
Family|Carb_B_Nematoda
Block| C
Position in NCBI Life Tree|Ascaris suum
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Nematoda: N E > Chromadorea: N E > Ascaridida: N E > Ascaridoidea: N E > Ascarididae: N E > Ascaris: N E > Ascaris suum: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acid identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : JI169660, AEUI02000240
1 UniProt : F1L1M9
2 UniProt : F1L1M9, A0A0M3HXK5
2 Interpro : F1L1M9, A0A0M3HXK5
2 Pfam : F1L1M9, A0A0M3HXK5
2 PIRSF : F1L1M9, A0A0M3HXK5
2 SUPERFAM : F1L1M9, A0A0M3HXK5
Sequence
Graphical view for this peptide sequence: ascsu-f1l1m9
Colored MSA for Carb_B_Nematoda (raw)
MGCSQSLPGRASIPQVVEIGSGKISGRSMLVDEGRSVNVFMGIPYAKPPV
GILRFQEPQPADRWDGVRNCLRHSPKAPQKELLIERFIASHVASSEDCLY
LNIFAPAWPPPQQQPNGFAVMVFIHGGAFAVHSSSFYGDIGICRSLCAKD
IIVVTIQYRLGILGFAATGDNSCIANLGLRDQTFALQWIKKNIWVFKGDP
DNITIAGQSAGGVCVDLLMLSPYSRGLFSKAIAISGTAECAWAMNDIRKV
CKALRFHALKIGWKCPGNANENAVNLSMMEFLKGKKASELSLGVRSLRKR
KDNIYGIDFAPVVDGDFFPEPIHELRRTAPKKICITGTTELEGLFFASYR
ERRYNEKAINSLISEFIKNSDEELKKKALALYPTEGKSKKEIIRTYMRLY
SDISVNNGVHAFAEQMVNAGHTVYLYNFQYHPQTFGAIGWAFPFIDATHG
TDLPYLFGKCIFTGAKFNANDFKMLDQYTKLITNFVKSGNPNEAGQSEWQ
PLTIDDTWRYYNIHLTSSMQADFQERRPAFWHALKEIPHESESATGSQDF
SSPNSRQVPQQVSSN
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MGCSQSLPGRASIPQVVEIGSGKISGRSMLVDEGRSVNVFMGIPYAKPPV
GILRFQEPQPADRWDGVRNCLRHSPKAPQKELLIERFIASHVASSEDCLY
LNIFAPAWPPPQQQPNGFAVMVFIHGGAFAVHSSSFYGDIGICRSLCAKD
IIVVTIQYRLGILGFAATGDNSCIANLGLRDQTFALQWIKKNIWVFKGDP
DNITIAGQSAGGVCVDLLMLSPYSRGLFSKAIAISGTAECAWAMNDIRKV
CKALRFHALKIGWKCPGNANENAVNLSMMEFLKGKKASELSLGVRSLRKR
KDNIYGIDFAPVVDGDFFPEPIHELRRTAPKKICITGTTELEGLFFASYR
ERRYNEKAINSLISEFIKNSDEELKKKALALYPTEGKSKKEIIRTYMRLY
SDISVNNGVHAFAEQMVNAGHTVYLYNFQYHPQTFGAIGWAFPFIDATHG
TDLPYLFGKCIFTGAKFNANDFKMLDQYTKLITNFVKSGNPNEAGQSEWQ
PLTIDDTWRYYNIHLTSSMQADFQERRPAFWHALKEIPHESESATGSQDF
SSPNSRQVPQQVSSN


References
    Title: Silencing of germline-expressed genes by DNA elimination in somatic cells
    Wang J, Mitreva M, Berriman M, Thorne A, Magrini V, Koutsovoulos G, Kumar S, Blaxter ML, Davis RE
    Ref: Dev Cell, 23:1072, 2012 : PubMed

            

    Title: Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles
    Wang J, Czech B, Crunk A, Wallace A, Mitreva M, Hannon GJ, Davis RE
    Ref: Genome Res, 21:1462, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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